Results 21 to 30 of about 1,030,335 (270)
NRF2 Is an Upstream Regulator of MYC-Mediated Osteoclastogenesis and Pathological Bone Erosion
Cells, 2020 Osteoclasts are the sole bone-resorbing cells that play an essential role in homeostatic bone remodeling and pathogenic bone destruction such as inflammatory arthritis.
Peter Sang Uk Park +5 more
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Cells, 2022 Cardiovascular diseases (CVDs) contribute to a large part of worldwide mortality. Similarly, two of the major risk factors for these diseases, aging and obesity, are also global problems.
Fiona Frederike Cox +6 more
doaj +1 more source
The M-CSF receptor in osteoclasts and beyond
Experimental and Molecular Medicine, 2020 Bone disease: Signaling pathway offers promising drug target Drugs directed at a key signaling receptor involved in breaking down bone tissue could help treat diseases marked by pathological bone loss and destruction. In a review article, Kyung-Hyun Park-
Se Hwan Mun +2 more
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Orthopaedic Surgery, 2022 The purpose of this network meta‐analysis was to investigate the efficacy and safety of total knee arthroplasty (TKA) considering seven different surgical approaches.
Jin‐long Zhao +7 more
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Bioactive Materials, 2023 The regeneration of alveolar bone is still clinical challenge, particularly accompanied with diabetes, causing metabolic disorder with a protracted low-grade inflammatory phenotype.
Pengfei Tian +9 more
doaj +1 more source
Four-Dimensional Painlev\'e-Type Equations Associated with Ramified Linear Equations III: Garnier Systems and Fuji-Suzuki Systems [PDF]
, 2017 This is the last part of a series of three papers entitled "Four-dimensional Painlev\'e-type equations associated with ramified linear equations". In this series of papers we aim to construct the complete degeneration scheme of four-dimensional Painlev ...
Kawakami, Hiroshi
core +1 more source
AMPK Signaling in Energy Control, Cartilage Biology, and Osteoarthritis
Frontiers in Cell and Developmental Biology, 2021 The adenosine monophosphate (AMP)–activated protein kinase (AMPK) was initially identified as an enzyme acting as an “energy sensor” in maintaining energy homeostasis via serine/threonine phosphorylation when low cellular adenosine triphosphate (ATP ...
Dan Yi +12 more
doaj +1 more source
Degenerate Elastic Networks [PDF]
The Journal of Geometric Analysis, 2020 AbstractWe minimize a linear combination of the length and the $$L^2$$ L 2 -norm of the curvature among networks in $$\mathbb {R}^d$$ R d
Giacomo Del Nin +2 more
openaire +7 more sources
Nature Communications, 2018 The human TNFAIP3 gene, which encodes for A20, is associated with autoimmune diseases. Here, the authors use BAC transgenics combined with CRISPR- and recombineering-mediated genome editing to dissect in vivo and in primary immune cells, the role of ...
Upneet K. Sokhi +9 more
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Molecular profiling of resident and infiltrating mononuclear phagocytes during rapid adult retinal degeneration using single-cell RNA sequencing. [PDF]
, 2019 Neuroinflammation commonly accompanies neurodegeneration, but the specific roles of resident and infiltrating immune cells during degeneration remains controversial.
Burns, Marie E +3 more
core +2 more sources