Results 91 to 100 of about 60,871 (285)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Degradabilidade in situ da matéria seca, proteína bruta e fibra em detergente neutro de algumas gramíneas sob pastejo contínuo In situ dry matter, crude protein, and neutral detergent fiber degradability of some grasses in continuous grazing

Revista Brasileira de Zootecnia, 2004
Foram avaliadas a cinética de degradação e a degradabilidade efetiva (DE) da matéria seca (MS), fibra em detergente neutro (FDN) e proteína bruta (PB) com ou sem correção para contaminação por proteína de origem microbiana da aveia preta, capim-Mombaça ...
Ivanor Nunes do Prado, Fernanda Barros Moreira, Lúcia Maria Zeoula, Fábio Yoshimi Wada, Ivone Yurika Mizubuti, Carolina Antunes Neves   +5 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

RUMINAL FERMENTATION AND TANNINS BIOACTIVITY OF SOME BROWSES USING A SEMI-AUTOMATED GAS PRODUCTION TECHNIQUE

Tropical and Subtropical Agroecosystems, 2009
The nutritive value, tannins bioactivity and methane production of some tropical plants e.g. Acacia (Acacia saligna), Leucaena (Leucaena leucocephala), Atriplex (Atriplex caseneace), Eucalyptus (Eucalytus globules), and Alfalafa (Medicago sativa) hay ...
Sobhy M.A. Sallam, Ives Claudio da Silve Bueno, Patricia Barbosa Godoy, Eduardo Fernando Nozella, Dorinha M.S.S. Vitti, Adibe Luiz Abdalla   +5 more
doaj  

Bayesian analysis for comparison of nonlinear regression model parameters: an application to ruminal degradability data Metodologia Bayesiana para comparação de parâmetros de modelos de regressão não-linear: uma aplicação a dados de degradabilidade ruminal

Revista Brasileira de Zootecnia, 2010
This paper shows the Bayesian approach as an alternative to the classical analysis of nonlinear models for ruminal degradation data. The data set was obtained from a Latin square experimental design, established for testing the ruminal degradation of dry
Robson Marcelo Rossi, Elias Nunes Martins, Terezinha Aparecida Guedes, Clóves Cabreira Jobim   +3 more
doaj   +1 more source

Enhanced antigen presentation and immunostimulation of dendritic cells using acid-degradable cationic nanoparticles. [PDF]

, 2005
Acid-degradable cationic nanoparticles encapsulating a model antigen (i.e., ovalbumin) were prepared by inverse microemulsion polymerization with acid-cleavable acetal cross-linkers.
Fréchet, Jean MJ, Goh, Sarah L, Kwon, Young Jik, Standley, Stephany M   +3 more
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Parâmetros de degradabilidade potencial da matéria seca e da proteína bruta das silagens de seis genótipos de sorgo (Sorghum bicolor (L.) Moench), com e sem tanino no grão, avaliados pela técnica in situ Potential degradability parameters of the dry matter and crude protein of six sorghum silage genotypes (Sorghum bicolor (L.) Moench), with or without tannin on grain, evaluated by in situ technique

Revista Brasileira de Zootecnia, 2003
Para testar o efeito da presença de tanino no grão sobre os parâmetros de degradabilidade potencial da matéria seca e da proteína bruta de seis genótipos de sorgo para silagem, foi conduzido um experimento utilizando a técnica da degradabilidade in situ.
Lívio Ribeiro Molina, Norberto Mario Rodriguez, Breno Mourão de Sousa, Lúcio Carlos Gonçalves, Iran Borges   +4 more
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Degradação ruminal e estimativa de consumo de genótipos de capim-elefante anão Ruminal degradation and intake prediction of the dwarf elephant grass genotypes

Revista Brasileira de Zootecnia, 2010
Os objetivos neste estudo foram avaliar a degradação ruminal in situ da matéria seca (MS) e da fibra em detergente neutro (FDN) e estimar o consumo de matéria seca de genótipos de capim-elefante anão em diferentes intervalos de corte.
Saulo Alberto do Carmo Araújo, Hernán Maldonado Vásquez, José Fernando Coelho da Silva, Bruno Borges Deminicis, Patrícia Regina de Souza Siqueira Campos, Fábio Nunes Lista   +5 more
doaj   +1 more source