Results 101 to 110 of about 60,871 (285)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Comparison of Noisy Channels and Reverse Data-Processing Theorems
, 2017 This paper considers the comparison of noisy channels from the viewpoint of statistical decision theory. Various orderings are discussed, all formalizing the idea that one channel is "better" than another for information transmission.
Buscemi, Francesco
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2007 The total and undegradable fractions of nitrogenous compounds associated to cell wall organic matrix in some tropical forages were evaluated. Samples of corn silage, elephantgrass silage and sugarcane were used.
L.T. Henriques +5 more
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Acta Scientiarum: Animal Sciences, 2015 This study aimed to evaluate the in vitro degradation and total gas production of different oil seed press cakes from a biodiesel production chain gas through the use of a semi-automatic technique of gas production in vitro.
Raissa Kiara oliveira de Morais +5 more
doaj +1 more source
Organic protein feed and edible oil from oilseed crops [PDF]
"Organic protein feed and edible oil from oilseed crops" is a four year research project with the aim of obtaining new knowledge for secure production of high-quality proteins for livestock feeds and edible oil for human consumption in Norwegian organic ...
core
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Investigating Degradation in Extrusion-Processed Bio-Based Composites Enhanced with Clay Nanofillers
BiomassThis research investigates the extrusion-based fabrication and characterization of nanocomposites derived from bio-sourced polypropylene (PP) and poly(butylene succinate) (PBS: a biodegradable polymer derived from renewable biomass sources such as corn ...
Ahmed Tara +5 more
doaj +1 more source