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Effects of Adding Butyrate or Exogenous Fibrolytic Enzymes on Ruminal Epithelium, Metabolism, and Microbiota of Beef Cattle. [PDF]
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To Degrade or Not to Degrade DNMT3A
Cancer Discovery, 2022Abstract Summary: Aberrant DNA cytosine methylation is a critical contributor to compromised tissue regeneration and malignant transformation, particularly during aging. In this issue of Cancer Discovery, Huang and colleagues define a new class of disease-associated DNA (cytosine-5-)-methyltransferase
Yuhong, Ma, Britta, Will
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Protein folding and degradation in bacteria:¶To degrade or not to degrade? That is the question
Cellular and Molecular Life Sciences, 2002In Escherichia coli protein quality control is carried out by a protein network, comprising chaperones and proteases. Central to this network are two protein families, the AAA+ and the Hsp70 family. The major Hsp70 chaperone. DnaK, efficiently prevents protein aggregation and supports the refolding of damaged proteins. In a special case, DnaK, together
Dougan, David A. +2 more
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Annual Review of Plant Biology, 2005
Recent research reveals that starch degradation in Arabidopsis leaves at night is significantly different from the “textbook” version of this process. Although parts of the pathway are now understood, other parts remain to be discovered. Glucans derived from starch granules are hydrolyzed via β-amylase to maltose, which is exported from the ...
Smith, Alison M. +2 more
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Recent research reveals that starch degradation in Arabidopsis leaves at night is significantly different from the “textbook” version of this process. Although parts of the pathway are now understood, other parts remain to be discovered. Glucans derived from starch granules are hydrolyzed via β-amylase to maltose, which is exported from the ...
Smith, Alison M. +2 more
openaire +3 more sources
Science Signaling, 2010
In vivo protein stoichiometries are regulated through N-terminally acetylated degrons.
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In vivo protein stoichiometries are regulated through N-terminally acetylated degrons.
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Targeted protein degradation and the enzymology of degraders
Current Opinion in Chemical Biology, 2018Targeted protein degradation is an emerging strategy for drug discovery that employs small molecules to catalyze the ubiquitination of target proteins, ultimately causing their degradation by the proteasome. Current degrader designs employ hetero-bivalent molecules to recruit E3 ubiquitin ligases such as VHL, Cereblon, and the IAPs to the target ...
Stewart L, Fisher, Andrew J, Phillips
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Impact of Lignin Structure and Cell Wall Reticulation on Maize Cell Wall Degradability
In this study, eight maize recombinant inbred lines were selected to assess both the impact of lignin structure and the impact of cell wall reticulation by p-hydroxycinnamic acids on cell wall degradability independently of the main "lignin content ...
Brigitte Pollet +2 more
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Science, 2017
Suitably designed degradable polymers can play a role in reducing plastic ...
Ann-Christine, Albertsson +1 more
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Suitably designed degradable polymers can play a role in reducing plastic ...
Ann-Christine, Albertsson +1 more
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