Results 91 to 100 of about 4,145,184 (301)

An oncopeptide regulates m6A recognition by the m6A reader IGF2BP1 and tumorigenesis

Nature Communications, 2020
The involvement of long non-coding RNA (lncRNA) in the regulation of N6-methyladenosine (m6A) modification of RNA is unclear. Here, the authors show that LINC00266-1 encodes a peptide that binds to m6A reader, IGF2BP1 to enhance the recognition of m6A ...
Song Zhu, Ji-Zhong Wang, De Chen, Yu-Tian He, Nan Meng, Min Chen, Rui-Xun Lu, Xin-Hui Chen, Xiao-Lan Zhang, Guang-Rong Yan   +9 more
doaj   +1 more source

Synthesis of 5 mol% Ga3+-doped SnP2O7/KPO3 composite electrolyte for intermediate temperature fuel cells

International Journal of Electrochemical Science, 2020
In this study, 5 mol% Ga3+-doped SnP2O7 / corresponding metaphosphate composite electrolyte was prepared. Synthesis and intermediate temperature electrical properties of Sn0.95Ga0.05P2O7/KPO3 were investigated.
Yan Han, Jingjing Zhu, Peng Sun, Nan Wang   +3 more
doaj   +1 more source

Degradation in Field-aged Crystalline Silicon Photovoltaic Modules and Diagnosis using Electroluminescence Imaging [PDF]

, 2016
Degradation phenomena observed in field-aged crystalline silicon photovoltaic modules include EVA browning, delamination between the glass-encapsulant and the cell-encapsulant interfaces, degradation of the anti-reflective coating, corrosion of busbars ...
Kaplani, Eleni
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Integrated machine learning identifies biomarkers for bilirubin-induced Alzheimer’s disease-like lesions in neonates and adults

Scientific Reports
Neurological impairments resulting from bilirubin encephalopathy represent a hallmark of bilirubin’s neurotoxic effects. Earlier research suggests that bilirubin may contribute to Alzheimer’s disease (AD) pathology by inducing neuronal necrosis and ...
Wenhao Bao, Han Chen, Zhuojun Zhang, Jiawen Wu, Jiaqian Lin, Daolin Tang, Jinbao Liu   +6 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

An efficient bacterial laccase-mediated system for polyurethane foam degradation

Frontiers in Microbiology
Polyurethane (PU), a segmented block copolymer with chemically resistant urethane linkages and tunable architecture, presents persistent biological recycling challenges. This study presents a Bacterial Laccase-Mediated System (BLMS) derived from Bacillus
Xiaomin Zhu, Youren Duan, Jianqi Lu, Wei Xia, Yujia Peng, Jiawei Liu, Weiliang Dong, Weiliang Dong, Min Jiang, Min Jiang   +9 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Peptides/Proteins Encoded by Non-coding RNA: A Novel Resource Bank for Drug Targets and Biomarkers

Frontiers in Pharmacology, 2018
Non-coding RNAs (ncRNAs) are defined as RNA molecules that do not encode proteins, but recent evidence has proven that peptides/proteins encoded by ncRNAs do indeed exist and usually contain less than 100 amino acids.
Song Zhu, Song Zhu, Jizhong Wang, Jizhong Wang, Yutian He, Yutian He, Nan Meng, Nan Meng, Guang-Rong Yan, Guang-Rong Yan   +9 more
doaj   +1 more source

Evaluating applicability of multi-source precipitation datasets for runoff simulation of small watersheds: a case study in the United States

European Journal of Remote Sensing, 2020
Small watersheds are ideal objects for studying the evolution of hydrological and water resources at small scales. Whether precipitation products can meet the runoff simulation of small watersheds is the main purpose of this study.
Kepeng Feng, Yang Hong, Juncang Tian, Xiangyu Luo, Guoqiang Tang, Guangyuan Kan   +5 more
doaj   +1 more source