Results 111 to 120 of about 2,986,953 (305)

Rural Poverty and Land Degradation: A Review of the Current State of Knowledge [PDF]

open access: yes
By highlighting the lack of rigorous evidence and calling for a greater understanding of the interaction of the two processes, a recent study [Nelson et al. (1997)] has called into question the strong perception that poverty is both a consequence as well
Hina Nazli, Sohail Jehangir Malik
core  

Odour perception – A rapid and easy method to detect early degradation of polymers

open access: yes, 2012
Human perception of odour is presented as a tool to detect early degradation of polymeric materials. Polyamide 66 (PA66) was selected as model material and subjected to accelerated ageing through thermo-oxidation.
Lindqvist, Anna,   +12 more
core   +1 more source

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim   +4 more
wiley   +1 more source

Degradation of pesticides by the ligninolytic enzyme Laccase : optimisation of in vitro conditions, immobilisation and screening for natural mediators [PDF]

open access: yes, 2013
Pesticides are widely used in many industries but the majority reaches non-target organisms or locations through point or diffuse sources. Understanding conditions for their degradation is therefore important.
Farragher, Naomi
core   +1 more source

The economics of land degradation and technological change: a case study in Vietnam [PDF]

open access: yes
This paper explores the economics of land degradation in the rice-shrimp system in the Mekong Delta of Vietnam. A bioeconomic NPV model was developed to evaluate and compare the long-term benefits of alternative production choices and farm technologies ...
Brennan, Donna C., Clayton, Helena
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Degradation of floor adhesives as a function of pH

open access: yes, 2008
Floor adhesives on cement-based substrates may degrade if the pH is high enough and this has in many cases led to emissions of odorous substances and deteriorated indoor air quality.
Anderberg, Anders,   +6 more
core   +2 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Mechanical Degradation Of Polypropylene: Effect Of Uv Irradiation

open access: yes, 1993
In studies of polymer degradation, one relates physical and chemical property changes to ageing conditions under the effect, usually, of a single initiating process. In order to study the possible existence of associated effects in the combined photo and
De Paoli M.-A.   +5 more
core   +1 more source

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