Results 111 to 120 of about 1,180,459 (201)

The economics of desertification, land degradation, and drought: Toward an integrated global assessment [PDF]

open access: yes
cost of inaction, desertification, drought, Economics, Land degradation, prevention of land degradation,
Graw, Valerie   +8 more
core  

Handbook of environmental degradation of materials /

open access: yes, 2005
Industry pays an enormous price for material degradation. The Handbook of Environmental Degradation of Materials outlines these costs, but more importantly, explains how to measure, analyze, and prevent environmental degradation for a wide range of ...
Kutz, Myer.edt
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Study on pre processing and storage conditions for extraction of chlorophyll from altemantherasessilis (L.) and knetics of degradation of chlorophyll

open access: yes, 2019
Extraction of chlorophyll from various plants is a key topic of scientific and commercial interest Altemantherasessilis was used for theextraction of chlorophyll as a locally available plant in Sri Lanka.
Amarasinghe, BMWPK   +3 more
core  

Follicle-stimulating hormone promotes EndMT in endothelial cells by upregulating ALKBH5 expression

open access: yesCellular & Molecular Biology Letters
Background The incidence of atherosclerosis markedly rises following menopause. Our previous findings demonstrated that elevated follicle-stimulating hormone (FSH) levels in postmenopausal women accelerate atherosclerosis progression. Plaque instability,
Ping Li   +8 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

open access: yesMolecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Land Degradation in Environmentally Sensitive Areas (ESA)

open access: yes
As global population growth intensifies pressure on land, land degradation has become a critical issue, costing approximately USD 490 billion annually and resulting in trillions in lost ecosystem services. According to the IPCC (2019), 70% of the Earth’s

core   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

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