Results 101 to 110 of about 2,986,953 (305)
PGRP-SC–mediated innate immune memory against pathogenic bacteria in Drosophila
hLifeTrained immunity is essential for innate immune cells to retain a memory of previously encountered pathogens, strengthening the hosts’ response against these pathogens. However, the mechanisms governing trained immunity have not been well elucidated.
Zihao Deng +9 more
doaj +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Handbook of Environmental Degradation of Materials
, 2012 Nothing stays the same for ever. The environmental degradation and corrosion of materials is inevitable and affects most aspects of life. In industrial settings, this inescapable fact has very significant financial, safety and environmental implications.
Kutz, Myer
core
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
International Journal of Electrochemical Science, 2018 In this work, novel SrCe0.9Yb0.1O3-α-(Li/Na)2CO3 (SCYb-LN) and SrCe0.9Yb0.1O3-α-LiCl-SrCl2 (SCYb-LS) electrolyte composites were successfully fabricated at low temperature. The SEM image results show that the composites possess sufficient density.
Lin Sun +3 more
doaj +1 more source
Poverty and Environmental Degradation: Searching for Theoretical Linkages [PDF]
Existing literature about poverty and environmental degradation suggests that poverty is the victim of environmental degradation, but could not conclude whether poverty is also the cause of environmental problems.
Arief Anshory Yusuf
core
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Peptides/Proteins Encoded by Non-coding RNA: A Novel Resource Bank for Drug Targets and Biomarkers
Frontiers in Pharmacology, 2018 Non-coding RNAs (ncRNAs) are defined as RNA molecules that do not encode proteins, but recent evidence has proven that peptides/proteins encoded by ncRNAs do indeed exist and usually contain less than 100 amino acids.
Song Zhu +9 more
doaj +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source