Results 51 to 60 of about 4,509,963 (335)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Background Gradual loss of terminal differentiation markers and gain of stem cell-like properties is a major hall mark of cancer malignant progression.
Mei-Mei Li +11 more
doaj +1 more source
Testing the orthodoxies of land degradation policy in Swaziland [PDF]
This paper explores Swaziland's National Action Programme (NAP) to combat desertification; the country's main strategy for implementing the United Nations Convention to Combat Desertification (UNCCD).
Stringer, L.C.
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Method for quantification of microplastic release from plastic-based materials during weathering
Most microplastics (MPs) are generated as a result of photodegradation during the life of plastic products and after the end-of-life as mismanaged waste.
Edgars Kuka +7 more
doaj +1 more source
Soil structural degradation and nutrient limitations across land use categories and climatic zones in Southern Africa [PDF]
Although soil degradation is a major threat to food security and carbon sequestration, our knowledge of the spatial extent of the problem and its drivers is very limited in Southern Africa.
Kihara, Job +6 more
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
The effect of microwave treatment on the tensile properties of treated sugar palm fibre with 6% NaOH reinforced thermoplastic polyurethane composites was investigated. Firstly, the sugar palm fibres were treated by 6% alkali solution.
A.A. Mohammed +3 more
doaj +1 more source
UV Degradation of the Optical Properties of Acrylic for Neutrino and Dark Matter Experiments [PDF]
UV-transmitting (UVT) acrylic is a commonly used light-propagating material in neutrino and dark matter detectors as it has low intrinsic radioactivity and exhibits low absorption in the detectors' light producing regions, from 350 nm to 500 nm ...
+16 more
core +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

