Results 51 to 60 of about 4,509,963 (335)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Development of an oncogenic dedifferentiation SOX signature with prognostic significance in hepatocellular carcinoma

open access: yesBMC Cancer, 2019
Background Gradual loss of terminal differentiation markers and gain of stem cell-like properties is a major hall mark of cancer malignant progression.
Mei-Mei Li   +11 more
doaj   +1 more source

Testing the orthodoxies of land degradation policy in Swaziland [PDF]

open access: yes, 2009
This paper explores Swaziland's National Action Programme (NAP) to combat desertification; the country's main strategy for implementing the United Nations Convention to Combat Desertification (UNCCD).
Stringer, L.C.
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Method for quantification of microplastic release from plastic-based materials during weathering

open access: yesMicroplastics and Nanoplastics
Most microplastics (MPs) are generated as a result of photodegradation during the life of plastic products and after the end-of-life as mismanaged waste.
Edgars Kuka   +7 more
doaj   +1 more source

Soil structural degradation and nutrient limitations across land use categories and climatic zones in Southern Africa [PDF]

open access: yes, 2019
Although soil degradation is a major threat to food security and carbon sequestration, our knowledge of the spatial extent of the problem and its drivers is very limited in Southern Africa.
Kihara, Job   +6 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Effect of microwave treatment on tensile properties of sugar palm fibre reinforced thermoplastic polyurethane composites

open access: yesDefence Technology, 2018
The effect of microwave treatment on the tensile properties of treated sugar palm fibre with 6% NaOH reinforced thermoplastic polyurethane composites was investigated. Firstly, the sugar palm fibres were treated by 6% alkali solution.
A.A. Mohammed   +3 more
doaj   +1 more source

UV Degradation of the Optical Properties of Acrylic for Neutrino and Dark Matter Experiments [PDF]

open access: yes, 2009
UV-transmitting (UVT) acrylic is a commonly used light-propagating material in neutrino and dark matter detectors as it has low intrinsic radioactivity and exhibits low absorption in the detectors' light producing regions, from 350 nm to 500 nm ...
  +16 more
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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