Results 61 to 70 of about 1,180,459 (201)

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

A Survey of the Modeling and Application on Non-destructive and Destructive Degradation Tests

open access: yes, 2017
These days, most products are highly reliable which makes it very difficult or even impossible to obtain failure data on such products within a reasonable period of time prior to product release. Degradation tests are one way to overcome this obstacle by
Chih-Chun Tsai   +3 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Study of the Electrical Conductivity of Al(III) Doped Sr0.6Na0.4SiO3-a

open access: yesInternational Journal of Electrochemical Science, 2019
Sr1-xNaxSiO3-0.5x is receiving worldwide attention as the fast oxide ion conductor. Sr0.6Na0.4Si0.9Al0.1O3- a and Sro.6Nao.4SiO3—α were successfully fabricated using a solid state synthesis method and characterized with X-ray diffractometer (XRD) and ...
Ruijuan Shi   +3 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Leveraging Synergies from Integrative Land-Biodiversity-Climate Action for Improving Monitoring, Reporting, and Investments into Land Restoration in Uzbekistan

open access: yes
This concise brief targets policymakers, summarizing the key messages of the Uzbekistan case study. It highlights that land degradation has cost the country around USD 3 billion and outlines integrated investment strategies aligned with LDN, NDCs, and ...
Economics of Land Degradation Initiative
core   +1 more source

Robust Controlled Degradation of Enzyme Loaded PCL‐Based Fibrous Scaffolds Toward Scarless Skin Tissue Regeneration

open access: yesAdvanced Science
Uncontrolled degradation of wound dressings may result in residues, causing several negative effects on wound healing, such as secondary damage, undesirable inflammation, and scar skin formation.
Lingling Fan   +7 more
doaj   +1 more source

Facile Synthesis and Enhanced Intermediate Temperature Electrical Properties of Novel Sn0.9Mg0.1P2O7/KSn2(PO4)3 Composite Electrolyte

open access: yesInternational Journal of Electrochemical Science, 2018
The application of Sn1-xMxP2O7 electrolyte for solid oxide fuel cells is limited due to its poor sintering abilities. In this study, a new Sn0.9Mg0.1P2O7/KSn2(PO4)3 composite electrolyte was facile synthesized and the structural and microstructural ...
Junlong Liu   +3 more
doaj   +1 more source

An oncopeptide regulates m6A recognition by the m6A reader IGF2BP1 and tumorigenesis

open access: yesNature Communications, 2020
The involvement of long non-coding RNA (lncRNA) in the regulation of N6-methyladenosine (m6A) modification of RNA is unclear. Here, the authors show that LINC00266-1 encodes a peptide that binds to m6A reader, IGF2BP1 to enhance the recognition of m6A ...
Song Zhu   +9 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

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