Rapid degradation of mutant SLC25A46 by the ubiquitin-proteasome system results in MFN1/2-mediated hyperfusion of mitochondria. [PDF]
SCL25A46 is a mitochondrial carrier protein that surprisingly localizes to the outer membrane and is distantly related to Ugo1. Here we show that a subset of SLC25A46 interacts with mitochondrial dynamics components and the MICOS complex.
Claypool, Steven M +6 more
core +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Novel Composite Electrolyte of Double-Doped Ceria-Sulphate for Medium Temperature Fuel Cells
In this study, Gd3+ and Er3+ double-doped CeO2 was synthesized by a microemulsion method. Ce0.8Er0.1Gd0.1O2-α-K2SO4-Li2SO4 composite electrolyte was prepared by mixing Ce0.8Er0.1Gd0.1O2-α powder with binary sulphates.
Wenbao Zhang +3 more
doaj +1 more source
Manganese-oxidizing bacteria mediate the degradation of 17α-ethinylestradiol [PDF]
Manganese (II) and manganese-oxidizing bacteria were used as an efficient biological system for the degradation of the xenoestrogen 17 alpha-ethinylestradiol (EE2) at trace concentrations.
Baker +22 more
core +2 more sources
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
High efficient catalytic degradation of tetracycline and ibuprofen using visible light driven novel Cu/Bi2Ti2O7/rGO nanocomposite::Kinetics, intermediates and mechanism [PDF]
The photoexcited charge carriers trapping was an effective way to generate a large number of active species like O-2(center dot-) and (OH)-O-center dot radicals to oxidize pharmaceutical molecules.
Acevedo, R. +4 more
core +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Background Dissolved organic matter (DOM) is the most active component of soil organic matter (SOM), playing a major role in regulating soil fertility and carbon cycling.
Rongjie Wu +10 more
doaj +1 more source
Correction to: Therapeutic efficacy of the novel SHP2 degrader SHP2-D26, alone or in combination, against lung cancer is associated with modulation of p70S6K/S6, Bim and Mcl-1 [PDF]
Yunfu Deng +8 more
openalex +1 more source
Photo-oxidative and soil burial degradation of irrigation tubes based on biodegradable polymer blends [PDF]
Irrigation tubes based on biodegradable polymers were prepared via an extrusion-drawing process by Irritec and compared to conventional pipes made of high-density polyethylene (HDPE).
Ceraulo M. +7 more
core +1 more source

