Results 101 to 110 of about 63,047 (307)

Recombinant Hypoallergenic Cat Allergy Vaccines

Allergy, EarlyView.
This study reports the construction and preclinical characterization of peptide‐carrier‐based vaccines combining all three important cat allergens (Fel d 1, Fel d 4 and Fel d 7) within single vaccine antigens, termed PreS‐Cat 1‐PreS‐Cat 5. Two subcutaneous immunizations of rabbits with PreS‐Cat 1‐5 induce equal or better antibodies blocking allergic ...
Daria Trifonova, Mirela Curin, Margarete Focke‐Tejkl, Zicheng Liu, Kristina Borochova, Pia Gattinger, Marianne van Hage, Hans Grönlund, Renata Kiss, Huey‐Jy Huang, Walter Keller, Ksenja Riabova, Antonina Karsonova, Michael Kundi, Inna Tulaeva, Daria Fomina, Alexander Karaulov, Rudolf Valenta   +17 more
wiley   +1 more source

Metabolic activity of phagocytosing granulocytes in chronic granulocytic leukemia: ultrastructural observation of a degranulation defect [PDF]

, 1977
Elisabeth M. Cramer, C Auclair, J Hakim, Evarist Feliú, J Boucherot, H Troube, JF Bernard, E Bergogne, P Boivin   +8 more
openalex   +1 more source

Anti‐KIT Barzolvolimab for Chronic Spontaneous Urticaria

Allergy, EarlyView.
We compared the efficacy and safety of four doses of barzolvolimab compared to placebo in reducing symptoms of chronic spontaneous urticaria in a randomized, controlled trial. Across barzolvolimab doses, rapid symptom reduction within 1 week was observed and sustained during 12 weeks.
Marcus Maurer, Martin Metz, John Anderson, Neetu Talreja, Diane Young, Elizabeth Crowley, Margo Heath‐Chiozzi, Rick Ma, Elsa Paradise, Thomas Hawthorne, Diego Alvarado, Jonathan A. Bernstein   +11 more
wiley   +1 more source

Basophil Activation Test: Bridging Allergy and Oncology for Diagnostic, Therapeutic and Prognostic Applications in AllergoOncology: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT The basophil activation test (BAT) is gaining increasing relevance as an ex vivo functional assay in allergy to evaluate IgE‐mediated hypersensitivity reactions to food allergens, venoms, and drugs and to monitor tolerance induction. Establishing universal standard operating protocols has been difficult, due to several challenges including ...
Mariona Pascal, Jitesh Chauhan, Edward Knol, Rodolfo Bianchini, Mariana Castells, Leticia De las Vecillas, Karin Hartmann, Elena Izquierdo, Uta Jappe, Teodorikez‐Wilfox Jimenez‐Rodriguez, Francesca Levi‐Schaffer, Cristobalina Mayorga, Aurélie Poli, Frank Redegeld, Alexandra F. Santos, Erika Jensen‐Jarolim, Christoph Bergmann, Sophia N. Karagiannis, Heather J. Bax   +18 more
wiley   +1 more source

Oncogenic Potential of Epstein-Barr Virus in NK and NKT Cells Contribute to the Rapid Deterioration of Hemophagocytic Lymphohistiocytosis. [PDF]

J Med Virol
ABSTRACT The rapid deterioration and fatal outcomes in Epstein‐Barr virus (EBV)‐related hemophagocytic lymphohistiocytosis (HLH) remain poorly understood. This study aimed to elucidate the key factors contributing to the progression of EBV‐HLH by comparing EBV cellular tropism and host immune responses between survivors and deceased patients.
Cui T, Huang M, Wang Y, Lin Z, Su X, Li W, Luo Q, Li K, Wang C, Zheng R, Wang Z.   +10 more
europepmc   +2 more sources

SEQUENTIAL DEGRANULATION OF THE TWO TYPES OF POLYMORPHONUCLEAR LEUKOCYTE GRANULES DURING PHAGOCYTOSIS OF MICROORGANISMS [PDF]

, 1973
D F Bainton
openalex   +1 more source

The Aetiology of Elevated Total Serum Immunoglobulin E in Children

Acta Paediatrica, EarlyView.
ABSTRACT Aim The paucity of real‐world data on the aetiology of elevated total serum immunoglobulin E (TS‐IgE) in children afflicts families and health care systems with diagnostic uncertainty. We explored a cohort of children with TS‐IgE levels over 1000 kU/L, focusing on the prevalence of atopic and non‐atopic conditions, the aetiology of extremely ...
Aliisa Ärölä, Kaarina Kukkonen, Svetlana Vakkilainen   +2 more
wiley   +1 more source

IL‐1R2 Expression in Tfr Cells Controls Allergic Anaphylaxis by Regulating IgG Versus IgE Responses

Allergy, EarlyView.
Paul Engeroff, Aude Belbezier, Romain Vaineau, Gwladys Fourcade, Hugo D. Lujan, Bertrand Bellier, Stephanie Graff‐Dubois, David Klatzmann   +7 more
wiley   +1 more source

Blockade of cannabinoid CB1 receptors potentiates the anti‐fibrotic effects mediated by SGLT2 inhibition in a mouse model of diabetic nephropathy

British Journal of Pharmacology, EarlyView.
Background and purpose Diabetic nephropathy (DN) is a common complication of diabetes. Current treatments include renin‐angiotensin‐aldosterone system (RAAS) blockers and sodium‐glucose co‐transporter 2 (SGLT2) inhibitors. The cannabinoid CB1 receptor is a potential therapeutic target.
Océane Pointeau, Awa Isma Ba, Audrey Geissler, Romain Barbosa, Abhishek Basu, Arif Muhammad, Marina Nivot, Maéva Loriot, Julia Leemput, Patricia Passilly‐Degrace, Sébastien Causse, Laurent Demizieux, Hélène François, Bruno Vergès, Jianmin Duan, Geneviève Gaucher, Michael Harvey, Pascal Degrace, Glenn Crater, Resat Cinar, Tony Jourdan   +20 more
wiley   +1 more source

DEGRANULATION OF POLYMORPHONUCLEAR LEUCOCYTES FOLLOWING PHAGOCYTOSIS OF MICROORGANISMS

, 1960
James G. Hirsch, Zanvil A. Cohn
openalex   +1 more source