Results 191 to 200 of about 137,298 (386)

Anti-inflammatory effects of Sanguisorbae Radix water extract on the suppression of mast cell degranulation and STAT-1/Jak-2 activation in BMMCs and HaCaT keratinocytes [PDF]

, 2016
Ju-Hye Yang, Jae‐Myung Yoo, Won‐Kyung Cho, Jin Yeul   +3 more
openalex   +1 more source

Cellular Mechanism and Key Insights in Allergen Immunotherapy for Allergic Rhinitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Allergic rhinitis (AR) arises from immune responses mediated by immunoglobulin E (IgE) to inhaled allergens, representing one of the most prevalent chronic conditions worldwide. Although AR may not be a serious ailment, it holds clinical relevance as it underpins numerous complications, serves as a major risk factor for suboptimal asthma ...
Zhe Wang, Teng‐Fei Li, Tian‐Yu Wang, Huan‐Hai Liu   +3 more
wiley   +1 more source

Hyperglycemia enhances coagulation and reduces neutrophil degranulation, whereas hyperinsulinemia inhibits fibrinolysis during human endotoxemia [PDF]

, 2008
Michiel E. Stegenga, Saskia N. van der Crabben, Regje M. E. Blümer, Marcel Levi, Joost C. M. Meijers, Mireille J. Serlie, Michael W.T. Tanck, Hans P. Sauerwein, Tom van der Poll   +8 more
openalex   +1 more source

Pathogenesis of Chemical Leukoderma and Chemical‐Induced Vitiligo

The Journal of Dermatology, EarlyView.
ABSTRACT Leukoderma/vitiligo is a serious pigmentary disorder that notably impairs the patient's quality of life. In particular, chemical leukoderma (CL)/vitiligo refers to acquired depigmentation of the skin induced by exposure to certain chemicals. In this review, the term “CL” is defined as the temporary, localized loss of pigmentation at the site ...
Yasutaka Kuroda, Lingli Yang, Ichiro Katayama   +2 more
wiley   +1 more source

The JAK1/JAK2‐ inhibitor ruxolitinib inhibits mast cell degranulation and cytokine release [PDF]

, 2018
Maud A.W. Hermans, Benjamin Schrijver, Conny C.P.A. van Holten‐Neelen, Roy Gerth van Wijk, P. Martin van Hagen, Paul Van Daele, Willem A. Dik   +6 more
openalex   +1 more source

The Proinflammatory Secretome of Senescent Cells Can Be Controlled by a HIF2A‐Dependent Upregulation and a FURIN‐Dependent Cleavage of the ANGPTL4 Secreted Factor

Aging Cell, EarlyView.
This article supports that ANGPTL4 secreted factor is induced transcriptionally and activated by proteolytic cleavage during senescence, contributing to the production of a pro‐inflammatory SASP. In the senescent cell microenvironment, ANGPTL4 could thus contribute to senescence‐dependent alterations such as inflammation and tumor initiation.
Gabriela Makulyte, Hasan Safwan‐Zaiter, Delphine Goehrig, Anda Huna, Adèle Mangelinck, Takumi Mikawa, Alberta Palazzo, Lyvia Moudombi, Jean‐Jacques Medard, Marie Chanal, Pacôme Lecot, Marie‐Cécile Michallet, Julie Gavard, Serge Adnot, Pierre Dubus, Hiroshi Kondoh, Carl Mann, Nguan Soon Tan, Philippe Bertolino, Jean‐Michel Flaman, David Bernard   +20 more
wiley   +1 more source

Different activation signals induce distinct mast cell degranulation strategies.

Journal of Clinical Investigation, 2016
N. Gaudenzio, Riccardo Sibilano, T. Marichal, P. Starkl, L. Reber, N. Cenac, Benjamin D. McNeil, Xinzhong Dong, Joseph D. Hernandez, R. Sagi-Eisenberg, I. Hammel, Axel Roers, S. Valitutti, M. Tsai, E. Espinosa, S. Galli   +15 more
semanticscholar   +1 more source

Rapid non-genomic inhibitory effects of glucocorticoids on human neutrophil degranulation [PDF]

, 2005
L. Liu, Y. X. Wang, Jiang‐Rui Zhou, Fei Long, Haijing Sun, Y. Liu, Y. Z. Chen, Chun‐Lei Jiang   +7 more
openalex   +1 more source

Review for "E‐Cadherin restricts mast cell degranulation in mice"

, 2021
Margarita Andorra
openalex   +1 more source

Molecular IgE Sensitization Profiling With Micro‐Arrayed Allergen Molecules in Adult Patients With Asthma From the LEAD Cohort: A Precision Medicine Approach

Allergy, EarlyView.
In the LEAD cohort, micro‐arrayed asthma allergens identified IgE‐sensitized adult asthma patients. Compared to non‐IgE‐sensitized patients, they had better lung function, took less ICS and had lower eosinophils. IgE‐sensitized patients were sensitized to a handful of respiratory allergen sources and may benefit from allergen‐specific forms of ...
Huey‐Jy Huang, Robab Breyer‐Kohansal, Katarzyna Niespodziana, Charmaine J. M. Lim, Marie‐Kathrin Breyer, Rudolf Valenta, Sylvia Hartl, the Allergochip Working Group, Maria‐Roxana Buzan, Kuan‐Wei Chen, Monica Daniela Cotarcă, Alexandra Dubovets, Pia Gattinger, Alexander Karaulov, Evgenii Kozlov, Carmen Panaitescu, Daria Trifonova, Mikhail Tulaev, Susanne Vrtala, Milena Weber, Lauriana‐Eunice Zbîrcea   +20 more
wiley   +1 more source