Results 1 to 10 of about 44,623 (260)
Autophagy Protects Against Eosinophil Cytolysis and Release of DNA
The presence of eosinophils in the airway is associated with asthma severity and risk of exacerbations. Eosinophils deposit their damaging products in airway tissue, likely by degranulation and cytolysis.
Stephane Esnault +2 more
exaly +4 more sources
Modulation of Reoviral Cytolysis (II): Cellular Stemness
Oncolytic viruses (OVs) are an emerging cancer therapeutic that are intended to act by selectively targeting and lysing cancerous cells and by stimulating anti-tumour immune responses, while leaving normal cells mainly unaffected.
Tarryn Bourhill +5 more
doaj +2 more sources
Mechanisms of Eosinophil Degranulation [PDF]
Eosinophils are highly granulated white blood and tissue cells that play complex roles in the immune system including host protection against helminthic parasites, viruses, fungi, and bacteria.
Sarah Almas, Paige Lacy
doaj +2 more sources
THE SIGNIFICANCE OF CYTOLYSIS SYNDROME IN CHILDREN [PDF]
The measurement of aminotransferases levels has become part of the routine biochemical tests done in children regardless of their clinical symptoms. Aminotransferases (ALT, AST) are tissue necrosis markers which change in both hepatic and extra-hepatic ...
Laura Mihaela Trandafir +4 more
doaj +2 more sources
Eosinophil Extracellular Traps in Health and Disease: From Host Defense to Chronic Inflammation [PDF]
Eosinophils are tissue-adapted granulocytes with important roles in host defense, immune regulation, barrier responses, and inflammatory disease. Beyond classical degranulation, activated eosinophils can release eosinophil extracellular traps (EETs ...
Bojan Stojanovic +5 more
doaj +2 more sources
Staphylococcus aureus is an important human pathogen that can cause a variety of diseases ranging from mild superficial skin infections to life-threatening conditions like necrotizing pneumonia, endocarditis, and septicemia. Polymorphonuclear leukocytes (
Viktoria Rungelrath +8 more
doaj +1 more source
Biomedical Relevance of Novel Anticancer Peptides in the Sensitive Treatment of Cancer
The global increase in cancer mortality and economic losses necessitates the cautious quest for therapeutic agents with compensatory advantages over conventional therapies.
Olalekan Olanrewaju Bakare +5 more
doaj +1 more source
Chronic HCV infection remains as a global health problem due to its wide prevalence, latent course without clinical manifestations, development of liver fibrosis with the eventual formation of cirrhosis and liver cancer, which largely leads to poor ...
T. I. Bevz +3 more
doaj +1 more source
Direct-acting anticancer (DAA) peptides are cytolytic peptides that show promise as novel anticancer agents. DAA peptides bind to anionic molecules that are abundant on cancer cells relative to normal healthy cells, which results in preferential killing ...
Ashley L. Hilchie +5 more
doaj +1 more source
The OBJECTIVE was to study the features of changes in the blood coagulation system that contribute to the development of postoperative complications in patients depending on the stage of non-tumor mechanical jaundice at admission.METHODS AND MATERIALS. A
V. E. Fedorov +4 more
doaj +1 more source

