, 2004 The paradigm states that inflammatory cells disappear from airway tissues through apoptosis and phagocytosis. However, cells may also be cleared through primary cytolysis, necrosis secondary to apoptosis, or transepithelial migration. This study examines
Andersson, Morgan, +5 more
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Integration of a virus membrane protein into the lipid bilayer of target cells as a prerequisite for immune cytolysis [PDF]
, 1979 Structural requirements for membrane antigens on target cells to mediate immune cytolysis were studied in a model system with purified membrane proteins from Semliki Forest virus (SFV). These SFV spike proteins were isolated in the form of detergent- and
Schirrmacher, V. +7 more
core +1 more source
The effect of cytoflavin on functional and metabolic parameters rat liver in pancreatonecrosis
Бюллетень сибирской медицины, 2012 Problem of diagnosis and treatment of patients with necrotizing pancreatitis is an urgent. So it is interesting to study the effectiveness of a multicomponent antihypoxant and antioxidant cytoflavin to reduce violations of the detoxifying properties of ...
M. S. Sukach, V. T. Dolgikh
doaj +1 more source
Current concepts of the pathogenesis of non-alcoholic fatty liver disease
Сахарный диабет, 2010 Non-alcoholic fatty liver disease (NAFLD) - common chronic liver disease, characterized by pathological accumulation of fat droplets, not associatedwith alcohol.
Evgenia Pavlovna Kosobyan +1 more
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Eosinophil Extracellular Traps and Inflammatory Pathologies—Untangling the Web!
Frontiers in Immunology, 2018 Eosinophils are an enigmatic white blood cell, whose immune functions are still under intense investigation. Classically, the eosinophil was considered to fulfill a protective role against parasitic infections, primarily large multicellular helminths ...
Manali Mukherjee +2 more
doaj +1 more source
The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes [PDF]
, 2018 Clearance of invading microbes requires phagocytes of the innate immune system. However, successful pathogens have evolved sophisticated strategies to evade immune killing.
Konig, A. +35 more
core +1 more source
Optimum marker selection of acute liver damage in rats in the experiment
RUDN Journal of Medicine, 2020 Relevance. Assessment of liver damage and functional state is one of the leading tasks of clinical and laboratory diagnostics. Traditionally used methods for determining the activity of a number of indicator enzymes in blood with relative organ ...
K. A. Popov +5 more
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Eosinophil cytolysis with or without ETosis in four cases of human gastric cancer: a comparative ultrastructural study [PDF]
Exploration of Targeted Anti-tumor TherapyThe ultrastructural morphology of eosinophil cytolysis and extracellular trap cell death (ETosis) has predominantly been examined in non-neoplastic eosinophil-associated diseases, with a limited investigation in neoplasms.
Rosario Caruso +2 more
doaj +1 more source
Defining potency of CAR+ T cells: Fast and furious or slow and steady
OncoImmunology, 2019 Genetically engineered T cells that express chimeric antigen receptors (CAR+) are heterogeneous and thus, understanding the immunotherapeutic efficacy remains a challenge in adoptive cell therapy.
Ivan Liadi +5 more
doaj +1 more source