Pathophysiology and emerging treatments for dermographic, cholinergic and cold urticaria
This review illustrates key proposed mast cell‐mediated activation pathways in dermographic, cholinergic and cold urticaria, highlighting IgE‐dependent and ‐independent mechanisms. These pathways are increasingly targeted by emerging drugs, aiming to interrupt mast cell activation and mediator release, offering more precise, mechanism‐based treatment ...
Mojca Bizjak‐Suran +2 more
wiley +1 more source
Management of chronic urticaria: Current status and future prospect
Chronic urticaria is driven by mast cell activation through autoimmune, inflammatory, and neuroimmune pathways. A structured approach combining diagnosis, patient‐reported outcomes, stepwise therapy, treatment optimization, monitoring and emerging targeted agents may improve disease control and enable more personalized management.
Andaç Salman +15 more
wiley +1 more source
Eosinophil-driven immunopathology exacerbates SARS-CoV-2 pneumonia in an OVA-induced airway allergy mouse model. [PDF]
Iketani T +7 more
europepmc +1 more source
Google searches show persistent use of outdated terminology for angioedema in Germany
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Sophia Neisinger +3 more
wiley +1 more source
ABSTRACT Objective Postoperative infection is a serious complication of bone augmentation procedures, potentially resulting in graft failure, basal bone resorption, and spread of infection to adjacent anatomic spaces. This paper introduces the CPR (Cleanse, Perfuse, and Retain) protocol and illustrates its clinical application in the management of low‐
Istvan A. Urban +2 more
wiley +1 more source
SHIP1 Restrains Hypoxia/Reoxygenation-Induced Cytokine Secretion in Mouse Bone Marrow-Derived Mast Cells. [PDF]
Gubeljak L +8 more
europepmc +1 more source
Genetic Susceptibility to Periodontitis
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley +1 more source
The Role of Zinc and Junctional Adhesion Molecule A Protein in Platelet Plug Formation. [PDF]
Nagidi SH +5 more
europepmc +1 more source
Inflammatory and Immunological Basis of Periodontal Diseases
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima +3 more
wiley +1 more source
Evaluation of <i>Rhinella marina</i> Extracts on the Effector Functions of Human Neutrophils. [PDF]
Albiero LR +11 more
europepmc +1 more source

