Results 261 to 270 of about 116,525 (341)

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Cytotoxic lymphocyte effector function is unaffected in patients with Gaucher disease. [PDF]

Front Immunol
Zou J, Noori T, Walterfang M, Szer J, Trapani JA, Voskoboinik I.   +5 more
europepmc   +1 more source

Targeting Inhibitory Siglec-3 to Suppress IgE-Mediated Human Basophil Degranulation

Suzanne Barshow, Md. Maidul Islam, Scott P. Commins, Matthew S. Macauley, James C. Paulson, Michael D. Kulis   +5 more
openalex   +1 more source

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

A Review of Acupuncture for Allergic Disorders: Modulation of Mast Cell Regulation via Inflammatory Pathway Suppression and Cytokine Balance. [PDF]

Int J Gen Med
Li Y, Meng Y, Chen C, Jiang K, Li J.
europepmc   +1 more source

Blood flow modification attached to HIFU exposure mast cell degranulation

, 2019
Д. Р. Файзуллина, V. V. Grizunov, A. E. Berkovich   +2 more
openalex   +2 more sources

Matrix Metalloproteinases in Periodontal and Peri‐Implant Diseases: Contribution to Their Pathogenesis, Diagnosis, and Treatment

Journal of Periodontal Research, EarlyView.
This graphical abstract illustrates the role of matrix metalloproteinases (MMPs) across the pathogenesis, diagnosis, and therapeutics of periodontal and peri‐implant diseases. Microbial and host stimuli trigger MMP activation leading to extracellular matrix breakdown, point‐of‐care aMMP‐8 detection aids diagnosis, and adjunctive or AI‐assisted ...
Timo Sorsa, Lorne M. Golub, Julie Toby Thomas, Pietro Leone, Sukumaran Anil, Veli‐Jukka Uitto   +5 more
wiley   +1 more source

Phenotypic, proteomic, and functional analyses of cytokine-induced memory-like NK cells show two distinct subsets based on CD16 expression. [PDF]

Sci Rep
Carreira-Santos S, González-Sánchez M, López-Sejas N, Hassouneh F, González-Fernández L, Jorge I, Durán E, Pera A, Vázquez J, Solana R, Tarazona R, Casado JG.   +11 more
europepmc   +1 more source

Nitrate Prevents Sjögren's Disease by Modulating T Helper Cells via NF‐κB Pathway Suppression

Oral Diseases, EarlyView.
ABSTRACT Objective Sjögren's disease (SjD) is a chronic autoimmune disease characterized by abnormal T helper (Th) cell distribution in the salivary glands (SGs). Although nitrate can regulate immune responses and preserve SGs function, its preventive effects on SjD remain unexplored.
Conglin Du, Zi Yang, Yang Yang, Chunmei Zhang, Hideaki Kagami, Xianqi Li, Liang Hu, Junji Xu, Jian Zhou   +8 more
wiley   +1 more source

Diagnosis of Periodontitis via Neutrophil Degranulation Signatures Identified by Integrated scRNA-Seq and Deep Learning. [PDF]

Genes (Basel)
Wu H, Huang L, Cai S, Xiong X, He Y.
europepmc   +1 more source