Results 261 to 270 of about 111,597 (294)
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Myeloperoxidase Stimulates Neutrophil Degranulation
Bulletin of Experimental Biology and Medicine, 2016Myeloperoxidase, heme enzyme of azurophilic granules in neutrophils, is released into the extracellular space in the inflammation foci. In neutrophils, it stimulates a dose-dependent release of lactoferrin (a protein of specific granules), lysozyme (a protein of specific and azurophilic granules), and elastase (a protein of azurophilic granules).
D V, Grigorieva +6 more
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Inflammation, 1981
A method is described for the quantitative monitoring of human eosinophil degranulation using interference contrast microscopy. Using staphyloccoci as a stimulus, degranulated cells appeared larger than nondegranulating cells, were ameboid in shape and exhibited large nude areas of cytoplasm with prominent nuclei.
R, Sher, A A, Wadee
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A method is described for the quantitative monitoring of human eosinophil degranulation using interference contrast microscopy. Using staphyloccoci as a stimulus, degranulated cells appeared larger than nondegranulating cells, were ameboid in shape and exhibited large nude areas of cytoplasm with prominent nuclei.
R, Sher, A A, Wadee
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Markers of Mast Cell Degranulation
Methods, 1997Mast cells are the primary effector cells of immediate hypersensitivity reactions in humans. Upon mast cell activation both preformed and newly synthesized mediators are secreted. Histamine can be measured by fluorometric assays, radioenzymatic assays, and immunoassays.
A D, Hogan, L B, Schwartz
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Neutrophil degranulation: therapeutic targets in [NTP]O mediated neutrophil degranulation
Medical Hypotheses, 2004Extracellular nucleotide-induced stimulation and activation of peripheral blood neutrophil and subsequent degranulation plays a critical role in immediate type hypersensitivity reaction and other inflammatory diseases. The extracellular nucleotides stimulate a P2Y receptor(s) on human PMN with the pharmacological profile similar to that of the P2Y2 ...
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Archives of Dermatology, 1965
A case report of coal tar hypersensitivity is presented. The clinical picture was one of psoriatic erythroderma. Confirmation of this hypersensitivity was demonstrated by observing morphologic changes in the circulating basophil following inhalation of crude coal tar vapor. Three control subjects showed no response to a similar challenge.
H M, PARNES, W B, SHELLEY
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A case report of coal tar hypersensitivity is presented. The clinical picture was one of psoriatic erythroderma. Confirmation of this hypersensitivity was demonstrated by observing morphologic changes in the circulating basophil following inhalation of crude coal tar vapor. Three control subjects showed no response to a similar challenge.
H M, PARNES, W B, SHELLEY
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Measuring Degranulation of Mast Cells
Current Protocols in Immunology, 1993AbstractThis unit describes methods for measuring exocytosis of preformed mediators from secretory granules as an indication of IgE receptor‐mediated activation of mast cells. The first basic protocol describes the measurement of biogenic amines (serotonin and histamine) secreted by activated rodent mast cells (for serotonin) or rodent and human mast ...
R J, Hohman, S C, Dreskin
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Allergo oncology: Targeted degranulation
Open Access Research Journal of Science and Technology, 2023Allergies are an inevitable part of life, no matter where we live. Without a doubt, the symptoms of allergies can cause severe physical and mental suffering. Although medical science has made great strides in suppressing allergy symptoms with medicines, immunotherapies, and virus-like particle technology (i.e., Allergy Vaccines), research indicates ...
null Michael John Dochniak +1 more
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Nephron, 2000
<i>Background/Aims: </i>Degranulation of polymorphonuclear leukocytes (PMN) during hemodialysis (HD) is usually assessed by measuring degranulation products. However, this process might also be estimated by the assessment of cell surface markers.
Grooteman, M P +6 more
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<i>Background/Aims: </i>Degranulation of polymorphonuclear leukocytes (PMN) during hemodialysis (HD) is usually assessed by measuring degranulation products. However, this process might also be estimated by the assessment of cell surface markers.
Grooteman, M P +6 more
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Cannabinoid induced degranulation of rabbit neutrophils
Biochemical and Biophysical Research Communications, 1982Abstract We have examined the effects of various cannabinoids on the degranulation of rabbit peritoneal neutrophils. Several cannabinoids were found to cause a dose-dependent and noncytotoxic release of lysosomal enzymes from the neutrophils. The degranulation induced by cannabidiol is rapid ( t 1 2 = 2.3 min ), and enhanced by ...
P H, Naccache +4 more
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Granulation-Degranulation Processes
2020In this chapter, we discuss the concept of information granulation and degranulation as one of the fundamental computing paradigms of Granular Computing supporting interaction with real-world environment. In the setting of fuzzy sets, the wording fuzzification-defuzzification is commonly used.
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