Results 261 to 270 of about 87,250 (304)
Some of the next articles are maybe not open access.
Neutrophil degranulation: therapeutic targets in [NTP]O mediated neutrophil degranulation
Medical Hypotheses, 2004Extracellular nucleotide-induced stimulation and activation of peripheral blood neutrophil and subsequent degranulation plays a critical role in immediate type hypersensitivity reaction and other inflammatory diseases. The extracellular nucleotides stimulate a P2Y receptor(s) on human PMN with the pharmacological profile similar to that of the P2Y2 ...
openaire +2 more sources
Thrombosis and Haemostasis, 1993
SummaryA new, simplified method of degranulating human platelets using the thrombin receptor peptide SFLLRN (20 |iM) is described; released fibrinogen cannot be converted to fibrin, and the platelets are not exposed to a proteolytic enzyme, as they are when thrombin is used for degranulation.
R L, Kinlough-Rathbone +4 more
openaire +2 more sources
SummaryA new, simplified method of degranulating human platelets using the thrombin receptor peptide SFLLRN (20 |iM) is described; released fibrinogen cannot be converted to fibrin, and the platelets are not exposed to a proteolytic enzyme, as they are when thrombin is used for degranulation.
R L, Kinlough-Rathbone +4 more
openaire +2 more sources
Archives of Dermatology, 1965
A case report of coal tar hypersensitivity is presented. The clinical picture was one of psoriatic erythroderma. Confirmation of this hypersensitivity was demonstrated by observing morphologic changes in the circulating basophil following inhalation of crude coal tar vapor. Three control subjects showed no response to a similar challenge.
H M, PARNES, W B, SHELLEY
openaire +2 more sources
A case report of coal tar hypersensitivity is presented. The clinical picture was one of psoriatic erythroderma. Confirmation of this hypersensitivity was demonstrated by observing morphologic changes in the circulating basophil following inhalation of crude coal tar vapor. Three control subjects showed no response to a similar challenge.
H M, PARNES, W B, SHELLEY
openaire +2 more sources
Cannabinoid induced degranulation of rabbit neutrophils
Biochemical and Biophysical Research Communications, 1982Abstract We have examined the effects of various cannabinoids on the degranulation of rabbit peritoneal neutrophils. Several cannabinoids were found to cause a dose-dependent and noncytotoxic release of lysosomal enzymes from the neutrophils. The degranulation induced by cannabidiol is rapid ( t 1 2 = 2.3 min ), and enhanced by ...
P H, Naccache +4 more
openaire +2 more sources
Optical Visualization of Microsomal Degranulation by a Carcinogen
Journal of Environmental Pathology, Toxicology and Oncology, 2001We report here for the first time the optical visualization of microsomal degranulation induced by a carcinogen (p-dimethylaminoazobenzene), employing analytical ultracentrifugation. Our observations demonstrate that electrophiles of a carcinogen can disrupt ribosome-membrane interaction in rough microsomes by their attacks on nucleophilic components ...
H M, Dani, P, Kaur
openaire +2 more sources
Degranulation of discoid platelets.
The American journal of pathology, 1972Platelet degranulation is a characteristic feature of platelet response to aggregating agents, but the mechanism and route by which secretory organelles are transferred to plasma are still uncertain. In the present study, human platelets were incubated with cytochalasin B, an agent which stabilizes discoid shape, and trypsin, which is known to cause ...
J G, White, R D, Estensen
openaire +1 more source
Granulation-Degranulation Processes
2020In this chapter, we discuss the concept of information granulation and degranulation as one of the fundamental computing paradigms of Granular Computing supporting interaction with real-world environment. In the setting of fuzzy sets, the wording fuzzification-defuzzification is commonly used.
openaire +1 more source
Distribution of the degranulated and non-degranulated mast cells in nasal polyp.
Acta oto-laryngologica. Supplementum, 1986All of the nasal polyps obtained from 83 patients had mast cells which stained with toluidine blue in their tissue. Degranulated mast cells occurred much more in the deep stroma than in the part near the surface of the polyp. More degranulation of mast cells should have occurred in the superficial tissue than in the deep stroma if the inhaled allergen ...
openaire +1 more source
Endogenous Sulfur Dioxide Is a Novel Inhibitor of Hypoxia-Induced Mast Cell Degranulation
Journal of Advanced Research, 2021Yaqian Huang, Junbao Du, Hongfang Jin
exaly