Results 91 to 100 of about 4,835,163 (282)
Existence of three solutions for a higher-order boundary-value problem
We consider a higher-order multi-point boundary-value problem with a nonlinear boundary condition. Sufficient conditions are obtained for the existence of three solutions.
John R. Graef, Lingju Kong, Qingkai Kong
doaj
Effective Degree Theory on Multiplex Networks for Concurrent Three-State Spreading Dynamics
We propose a model of concurrent three-state spreading dynamics on multiplex networks to study the co-evolution process of epidemic spreading and information diffusion.
Yinzuo Zhou, Cong Teng, Jie Zhou
doaj +1 more source
Tabular degrees in \Ga-recursion theory
This paper develops the foundations of a theory of truth-table reducibilities in the setting of \(\alpha\)-recursion. A generalization of \(tt\)-reducibility and several generalizations of weak-\(tt\)-reducibility are given and their properties explored. Most of the main results deal with regular sets. For example, for each of the reducibilities given,
Bailey, Colin, Downey, Rod
openaire +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Boundary-value problems for nonautonomous nonlinear systems on the half-line
A method is presented for proving the existence of solutions for boundary-value problems on the half line. The problems under study are nonlinear, nonautonomous systems of ODEs with the possibility of some prescribed value at $t=0$ and with the ...
Jason R. Morris
doaj
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
In this article, we consider the singular nonlinear elliptic problem $$displaylines{ -Delta u = g(u)+h( abla u)+f(u) quadhbox{in }Omega, cr u = 0 quadhbox{on }partialOmega.
Carlos C. Aranda
doaj
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
A Geometric Theory for Hypergraph Matching
We develop a theory for the existence of perfect matchings in hypergraphs under quite general conditions. Informally speaking, the obstructions to perfect matchings are geometric, and are of two distinct types: 'space barriers' from convex geometry, and '
Keevash, Peter, Mycroft, Richard
core

