Results 71 to 80 of about 708,969 (305)
Variational inequalities with the duality operator in Banach spaces
We study variational inequality by way of metric projection in Banach spaces. The main method is to use a topological degree theory for the class of operators of monotone type in Banach spaces. More precisely, some variational inequality associated with
In-Sook Kim
doaj
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Coexistence of steady state for a diffusive prey-predator model with harvesting
In this article, we study a diffusive prey-predator model with modified Leslie-Gower term and Michaelis-Menten type prey harvesting, subject to homogeneous Dirichlet boundary conditions.
Yan Li
doaj
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
This essay aims to reflect on some of the ways in which security surveillance technology has become politicised through race and gender biases, the product of a historical process known as cis-coloniality.
Mariah Rafaela Silva
doaj
Topological degree theory and applications
Since the 1960s, many researchers have extended topological degree theory to various non-compact type nonlinear mappings, and it has become a valuable tool in nonlinear analysis.
Chen, Yu-Qing, Cho, Yeol Je
core
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Star multigraphs with three vertices of maximum degree. [PDF]
The graphs we consider here are either simple graphs, that is they have no loops or multiple edges, or are multigraphs, that is they may have more than one edge joining a pair of vertices, but again have no loops.
Hilton, A. J. W., Chetwynd, Amanda G.
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source

