Results 71 to 80 of about 4,835,163 (282)

Variational inequalities with the duality operator in Banach spaces

open access: yesResults in Nonlinear Analysis, 2020
We study variational inequality by way of metric projection in Banach spaces. The main method is to use a topological degree theory for the class of operators of monotone type in Banach spaces. More precisely, some variational inequality associated with
In-Sook Kim
doaj  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Coexistence of steady state for a diffusive prey-predator model with harvesting

open access: yesElectronic Journal of Differential Equations, 2016
In this article, we study a diffusive prey-predator model with modified Leslie-Gower term and Michaelis-Menten type prey harvesting, subject to homogeneous Dirichlet boundary conditions.
Yan Li
doaj  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Degree Theory Beyond Continuous Maps [PDF]

open access: yes, 1996
The author gives an introductory overview (without proofs) on recent extensions of finite-dimensional degree theory to the non-continuous case. This is of particular interest in dealing with the Ginzburg-Landau equations. Let \(X,Y\) be compact connected Riemannian manifolds of the same dimension with \(Y\) smoothly embedded in some \(\mathbb{R}^{N}\).
openaire   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

NAVIGATING SCREENS

open access: yesSur: International Journal on Human Rights, 2021
This essay aims to reflect on some of the ways in which security surveillance technology has become politicised through race and gender biases, the product of a historical process known as cis-coloniality.
Mariah Rafaela Silva
doaj  

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Ambiguity, Pessimism, and Religious Choice [PDF]

open access: yes
Using a relatively mild restriction on the beliefs of the MMEU-apreference functional, in which the decision maker’s degree of ambiguity and degree of pessimism are each parameterized, we present a rather general theory of religious choice in the ...
Mark Pingle, Tigran Melkonyan
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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