Natural Products, Alone or in Combination with FDA-Approved Drugs, to Treat COVID-19 and Lung Cancer
As a public health emergency of international concern, the highly contagious coronavirus disease 2019 (COVID-19) pandemic has been identified as a severe threat to the lives of billions of individuals.
Liyan Yang, Zhonglei Wang
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Efikasi Pestisida Biorasional Untuk Mengendalikan Thrips Palmi Karny Pada Tanaman Kentang [PDF]
. Suryaningsih, E. 2008 . The Efficacy of Biorational Pesticides to Control ontrol Thrips palmi Karny on Potato Plant . In order to investigate an alternative pesticide, namely biorational pesticides, field experiment was conducted at Margahayu Research ...
Suryaningsih, E. (E)
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Mitochondrial Complex I Inhibitors Expose a Vulnerability for Selective Killing of Pten-Null Cells
Summary: A hallmark of advanced prostate cancer (PC) is the concomitant loss of PTEN and p53 function. To selectively eliminate such cells, we screened cytotoxic compounds on Pten−/−;Trp53−/− fibroblasts and their Pten-WT reference.
Adam Naguib +14 more
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SH-1242, a novel inhibitor of heat shock protein 90 (HSP90), is a synthetic analog of deguelin: It was previously reported that the treatment of SH-1242 led to a strong suppression of hypoxia-mediated retinal neovascularization and vascular leakage in ...
Yoo-Seong Jeong +7 more
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Categorical data analysis using a skewed Weibull regression model
In this paper, we present a Weibull link (skewed) model for categorical response data arising from binomial as well as multinomial model. We show that, for such types of categorical data, the most commonly used models (logit, probit and complementary log-
Caron, Renault +3 more
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High-throughput testing in head and neck squamous cell carcinoma identifies agents with preferential activity in human papillomavirus-positive or negative cell lines. [PDF]
Head and neck squamous cell carcinoma (HNSCC) is a common cancer diagnosis worldwide. Despite advances in treatment, HNSCC has very poor survival outcomes, emphasizing an ongoing need for development of improved therapeutic options.
Ailles, Laurie A +16 more
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Potential Compounds for Oral Cancer Treatment: Resveratrol, Nimbolide, Lovastatin, Bortezomib, Vorinostat, Berberine, Pterostilbene, Deguelin, Andrographolide, and Colchicine. [PDF]
Oral cancer is one of the main causes of cancer-related deaths in South-Asian countries. There are very limited treatment options available for oral cancer.
Saurabh Bundela +2 more
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The objective of this study was to determine the phytochemical compounds present in methanolic root and leaf extracts of Tephrosia vogelii. The plant species is found in the genus Tephrosia and family Fabaceae.
Stephano Hanolo Mlozi +2 more
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Standardization of the bio-active compounds (rotenoids) from the extract of local plant species (derris elliptica) using the internal standard method of high performance liquid chromatography (HPLC) [PDF]
It is well known now that some plant species represent an efficient factory of chemicals, which are manufactured and used as bio-weapons against pest attacks. Extensive work has been done during the last few decades on these potentially useful compounds.
M. R., Sarmidi +2 more
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Identification of compounds with anti-convulsant properties in a zebrafish model of epileptic seizures [PDF]
The availability of animal models of epileptic seizures provides opportunities to identify novel anticonvulsants for the treatment of people with epilepsy.
Anandahan +54 more
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