Natural Products, Alone or in Combination with FDA-Approved Drugs, to Treat COVID-19 and Lung Cancer
Biomedicines, 2021 As a public health emergency of international concern, the highly contagious coronavirus disease 2019 (COVID-19) pandemic has been identified as a severe threat to the lives of billions of individuals.
Liyan Yang, Zhonglei Wang
doaj +1 more source
High-throughput testing in head and neck squamous cell carcinoma identifies agents with preferential activity in human papillomavirus-positive or negative cell lines. [PDF]
, 2018 Head and neck squamous cell carcinoma (HNSCC) is a common cancer diagnosis worldwide. Despite advances in treatment, HNSCC has very poor survival outcomes, emphasizing an ongoing need for development of improved therapeutic options.
Ailles, Laurie A +16 more
core +1 more source
Mitochondrial Complex I Inhibitors Expose a Vulnerability for Selective Killing of Pten-Null Cells
Cell Reports, 2018 Summary: A hallmark of advanced prostate cancer (PC) is the concomitant loss of PTEN and p53 function. To selectively eliminate such cells, we screened cytotoxic compounds on Pten−/−;Trp53−/− fibroblasts and their Pten-WT reference.
Adam Naguib +14 more
doaj +1 more source
Molecules, 2020 SH-1242, a novel inhibitor of heat shock protein 90 (HSP90), is a synthetic analog of deguelin: It was previously reported that the treatment of SH-1242 led to a strong suppression of hypoxia-mediated retinal neovascularization and vascular leakage in ...
Yoo-Seong Jeong +7 more
doaj +1 more source
Categorical data analysis using a skewed Weibull regression model
, 2017 In this paper, we present a Weibull link (skewed) model for categorical response data arising from binomial as well as multinomial model. We show that, for such types of categorical data, the most commonly used models (logit, probit and complementary log-
Caron, Renault +3 more
core +2 more sources
Sifat Antibakteri dari Daun Tephrosia vogelii Terhadap Vibriosis
Αl-Kimiya: Jurnal Ilmu Kimia dan Terapan, 2019 Sektor kelautan dan perikanan merupakan salah satu sumber andalan dalam produksi pembangunan perikanan di Indonesia. Udang merupakan salah satu komoditas unggulan utama dalam menunjang produksi pendapatan devisa non migas.
Eri Bachtiar +2 more
doaj +1 more source
Potential Compounds for Oral Cancer Treatment: Resveratrol, Nimbolide, Lovastatin, Bortezomib, Vorinostat, Berberine, Pterostilbene, Deguelin, Andrographolide, and Colchicine. [PDF]
PLoS ONE, 2015 Oral cancer is one of the main causes of cancer-related deaths in South-Asian countries. There are very limited treatment options available for oral cancer.
Saurabh Bundela +2 more
doaj +1 more source
Scientific African, 2022 The objective of this study was to determine the phytochemical compounds present in methanolic root and leaf extracts of Tephrosia vogelii. The plant species is found in the genus Tephrosia and family Fabaceae.
Stephano Hanolo Mlozi +2 more
doaj +1 more source
Standardization of the bio-active compounds (rotenoids) from the extract of local plant species (derris elliptica) using the internal standard method of high performance liquid chromatography (HPLC) [PDF]
, 2005 It is well known now that some plant species represent an efficient factory of chemicals, which are manufactured and used as bio-weapons against pest attacks. Extensive work has been done during the last few decades on these potentially useful compounds.
M. R., Sarmidi +2 more
core
Identification of compounds with anti-convulsant properties in a zebrafish model of epileptic seizures [PDF]
, 2012 The availability of animal models of epileptic seizures provides opportunities to identify novel anticonvulsants for the treatment of people with epilepsy.
Anandahan +54 more
core +2 more sources