Results 61 to 70 of about 1,094 (192)

Morphine promotes the malignant biological behavior of non-small cell lung cancer cells through the MOR/Src/mTOR pathway

open access: yesCancer Cell International, 2021
Background Morphine, a µ-opioid receptor (MOR) agonist, has been shown to be related to the activity of cancer cells, and a higher morphine dosage reduces the survival time of patients with lung cancer.
Xingyun Liu   +6 more
doaj   +1 more source

Biosynthesis and Characterization of Ag3PO4/SnO2 Nanocomposites for Effective Photocatalytic Degradation of Rhodamine B and Biological Applications

open access: yesJournal of Nanotechnology, Volume 2025, Issue 1, 2025.
The current investigation focuses on the photocatalytic degradation and biological applications of M. sericea leaf extract‐mediated Ag3PO4/SnO2 nanocomposites (NCs). The synthesized nanomaterials were characterized through various characterization techniques to determine their structural and optical properties.
Vrushali Manoj Hadkar   +3 more
wiley   +1 more source

Deguelin inhibits human hepatocellular carcinoma by antiangiogenesis and apoptosis

open access: yesOncology Reports, 2008
Deguelin is a rotenoid isolated from several plant species, which has been reported to have chemopreventive effects in skin, mammary, colon and lung cancers. The effects of deguelin on the proliferation and apoptosis of hepatic cancer cells were assessed by MTT assay and flow cytometric analysis.
Ju-Hee, Lee   +5 more
openaire   +3 more sources

Deguelin down-regulates survivin and Cdk4.

open access: yes, 2013
Hep-2 cells were exposed to deguelin at indicated concentration (10, 25, 50 and 100 µM) for 24 hours, expression levels of survivin, Cdk4 and tubulin were measured by western blot (A).The association between survivin, Cdk4 and Hsp 90 as well as the ...
Chun-cheng Lu (276392)   +6 more
core   +1 more source

A Novel Lysosome‐Related Gene Signature Predicts Lung Cancer Prognosis: A Bioinformatics‐Driven Study

open access: yesHealth Science Reports, Volume 7, Issue 12, December 2024.
ABSTRACT Background and Aims The biological function of lysosomes has been increasingly appreciated in cancer. However, the relationship between lysosome and lung adenocarcinoma (LUAD) was not well understood. In this study, a lysosome‐related signature was developed for LUAD risk stratification and prognosis prediction.
Wei Ye   +4 more
wiley   +1 more source

Potentiation of fludarabine action by deguelin.

open access: yes, 2016
PBMCs from 2 CLL patients were treated with 10 μM deguelin, 1 μg/ml fludarabine or the combination of both, and co-cultured with 3T3-CD40L cell line up to 120h (same samples as in Fig 4B, 4C and 4D).
Silvia Rosado (39145)   +9 more
core   +1 more source

Brown Stink Bug Mortality by Seed Extracts of Tephrosia Vogelii Containing Deguelin and Tephrosin

open access: yesBrazilian Archives of Biology and Technology, 2018
Extracts of the seeds of Tephrosia vogelii Hook. f. were studied in relation to its chemical composition and toxicity to the brown stink bug Euschistus heros (F.).
Adriana Yatie Mikami   +2 more
doaj   +1 more source

Dietary phenolic compounds as promising therapeutic agents for diabetes and its complications: A comprehensive review

open access: yesFood Science &Nutrition, Volume 12, Issue 5, Page 3025-3045, May 2024.
Polyphenols, such as kaempferol, catechins, apigenin, chlorogenic acid, rosmarinic acid, and caffeic acid, have shown their ability to serve as potential antidiabetic medicines. Also, the use of polyphenols might have a few side effects although relatively less than available medications. Abstract In the middle of an ever‐changing landscape of diabetes
Dipa Aryal   +11 more
wiley   +1 more source

Deguelin activates AMPK signaling.

open access: yes, 2013
Hep-2 cells were exposed to 100 µM of deguelin for indicated time points, followed by western blot detecting phospho- and total- level of LKB1-AMPK-ACC using specific antibodies (A).
Chun-cheng Lu (276392)   +6 more
core   +1 more source

Preventing Cancer by Inhibiting Ornithine Decarboxylase: A Comparative Perspective on Synthetic vs. Natural Drugs

open access: yesChemistry &Biodiversity, Volume 21, Issue 4, April 2024.
Abstract This perspective delves into the investigation of synthetic and naturally occurring inhibitors, their patterns of inhibition, and the effectiveness of newly utilized natural compounds as inhibitors targeting the Ornithine decarboxylase enzyme. This enzyme is known to target the MYC oncogene, thereby establishing a connection between polyamine ...
Preeti Nanda Sahu, Anik Sen
wiley   +1 more source

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