Results 51 to 60 of about 747 (158)
Cancer Cell International, 2021 Background Morphine, a µ-opioid receptor (MOR) agonist, has been shown to be related to the activity of cancer cells, and a higher morphine dosage reduces the survival time of patients with lung cancer.
Xingyun Liu +6 more
doaj +1 more source
Journal of Nanotechnology, Volume 2025, Issue 1, 2025.The current investigation focuses on the photocatalytic degradation and biological applications of M. sericea leaf extract‐mediated Ag3PO4/SnO2 nanocomposites (NCs). The synthesized nanomaterials were characterized through various characterization techniques to determine their structural and optical properties.
Vrushali Manoj Hadkar +3 more
wiley +1 more source
Deguelin targets multiple oncogenic signaling pathways to combat human malignancies
Pharmacological Research, 2021 Cancer is an anomalous growth and differentiation of cells known to be governed by oncogenic factors. Plant-based natural metabolites have been well recognized to possess chemopreventive properties. Deguelin, a natural rotenoid, is among the class of bioactive phytoconstituents from a diverse range of plants with potential antineoplastic effects in ...
Hardeep Singh Tuli +11 more
openaire +2 more sources
Health Science Reports, Volume 7, Issue 12, December 2024.ABSTRACT Background and Aims The biological function of lysosomes has been increasingly appreciated in cancer. However, the relationship between lysosome and lung adenocarcinoma (LUAD) was not well understood. In this study, a lysosome‐related signature was developed for LUAD risk stratification and prognosis prediction.
Wei Ye +4 more
wiley +1 more source
Deguelin promotes apoptosis and inhibits angiogenesis of gastric cancer
Oncology Reports, 2010 Gastric cancer is often diagnosed in locally advanced or metastatic stages, which preludes a poor prognosis. As only 10% of patients with advanced gastric cancer treated with chemotherapy survive 2 years, new approaches for preventing and controlling the disease are required. We therefore, assessed in gastric cancer cells the chemotherapeutic potential
Hyunseung, Lee +3 more
openaire +3 more sources
Brown Stink Bug Mortality by Seed Extracts of Tephrosia Vogelii Containing Deguelin and Tephrosin
Brazilian Archives of Biology and Technology, 2018 Extracts of the seeds of Tephrosia vogelii Hook. f. were studied in relation to its chemical composition and toxicity to the brown stink bug Euschistus heros (F.).
Adriana Yatie Mikami +2 more
doaj +1 more source
Food Science &Nutrition, Volume 12, Issue 5, Page 3025-3045, May 2024.Polyphenols, such as kaempferol, catechins, apigenin, chlorogenic acid, rosmarinic acid, and caffeic acid, have shown their ability to serve as potential antidiabetic medicines. Also, the use of polyphenols might have a few side effects although relatively less than available medications. Abstract In the middle of an ever‐changing landscape of diabetes
Dipa Aryal +11 more
wiley +1 more source
Thin Layer Densitometric Determination of Rotenone and Deguelin
Journal of AOAC INTERNATIONAL, 1969 Abstract Rutenone and deguelin are separated by chromatography on silver nitrate-impregnated silica gel G with chloroform acetone: acetic acid (196:3:1) solvent system. Glass plates, 20 × 20 cm, are coated with a special spreader producing a 0.25 mm layer and a 1.00 mm band at the upper end.
William H Tallent, Norman E Delfel
openaire +1 more source
Chemistry &Biodiversity, Volume 21, Issue 4, April 2024.Abstract This perspective delves into the investigation of synthetic and naturally occurring inhibitors, their patterns of inhibition, and the effectiveness of newly utilized natural compounds as inhibitors targeting the Ornithine decarboxylase enzyme. This enzyme is known to target the MYC oncogene, thereby establishing a connection between polyamine ...
Preeti Nanda Sahu, Anik Sen
wiley +1 more source
Química Nova, 2012 In the search for new larvicides from plants, we have investigated the potential activity of the rotenoids deguelin (1), 12a-hydroxy-α-toxicarol (2) and tephrosin (3), isolated from the bioactive ethanol extract of roots of Tephrosia toxicaria Pers ...
Jackson Nunes e Vasconcelos +10 more
doaj +1 more source