Results 51 to 60 of about 1,019 (188)

Development and Validation of Analytical Method for SH-1242 in the Rat and Mouse Plasma by Liquid Chromatography/Tandem Mass Spectrometry

open access: yesMolecules, 2020
SH-1242, a novel inhibitor of heat shock protein 90 (HSP90), is a synthetic analog of deguelin: It was previously reported that the treatment of SH-1242 led to a strong suppression of hypoxia-mediated retinal neovascularization and vascular leakage in ...
Yoo-Seong Jeong   +7 more
doaj   +1 more source

Sifat Antibakteri dari Daun Tephrosia vogelii Terhadap Vibriosis

open access: yesΑl-Kimiya: Jurnal Ilmu Kimia dan Terapan, 2019
Sektor kelautan dan perikanan merupakan salah satu sumber andalan dalam produksi pembangunan perikanan di Indonesia. Udang merupakan salah satu komoditas unggulan utama dalam menunjang produksi pendapatan devisa non migas.
Eri Bachtiar   +2 more
doaj   +1 more source

Potential Compounds for Oral Cancer Treatment: Resveratrol, Nimbolide, Lovastatin, Bortezomib, Vorinostat, Berberine, Pterostilbene, Deguelin, Andrographolide, and Colchicine. [PDF]

open access: yesPLoS ONE, 2015
Oral cancer is one of the main causes of cancer-related deaths in South-Asian countries. There are very limited treatment options available for oral cancer.
Saurabh Bundela   +2 more
doaj   +1 more source

GC-MS analysis of bioactive phytochemicals from methanolic leaf and root extracts of Tephrosia vogelii

open access: yesScientific African, 2022
The objective of this study was to determine the phytochemical compounds present in methanolic root and leaf extracts of Tephrosia vogelii. The plant species is found in the genus Tephrosia and family Fabaceae.
Stephano Hanolo Mlozi   +2 more
doaj   +1 more source

Docking of deguelin on anti-apoptotic proteins.

open access: yes, 2016
(A) Structure of deguelin arrow indicates the binding of deguelin on Bcl-2 (B) The docking of deguelin on BH3 domain of hydrophobic group of anti-apoptotic protein Bcl-xl (C) Binding of deguelin on MCL-1 (D) Binding of deguelin molecule on ERK-1 near the
Ashraf Ali (625827)   +15 more
core   +1 more source

Ethnomedicinal Practices of the Fabaceae Family in Tanzania: A Systematic Review

open access: yesThe Scientific World Journal, Volume 2026, Issue 1, 2026.
This study is aimed at reviewing the ethnomedicinal, phytochemical and pharmacological properties of Fabaceae species used as sources of traditional medications in Tanzania. Using the Systematic Reviews and Meta‐Analyses (PRISMA) methodology, a comprehensive review was conducted on Fabaceae species used by Tanzanians through electronic databases such ...
David Sylvester Kacholi, Kalyani Sen
wiley   +1 more source

Deguelin down-regulates Akt signaling.

open access: yes, 2013
Hep-2 cells were exposed to deguelin at indicated concentration (10, 25, 50 and 100 µM) for 24 hours, total- and phospho- levels of Akt as well as phosphorylation level of S6K were measured by Western blot using indicated antibodies (A).The association ...
Chun-cheng Lu (276392)   +6 more
core   +1 more source

A Focus on Natural Autophagy Modulators as Potential Host‐Directed Weapons Against Emerging and Re‐Emerging Viruses

open access: yesMedicinal Research Reviews, Volume 45, Issue 6, Page 1850-1882, November 2025.
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro   +5 more
wiley   +1 more source

Specificity of Deguelin.

open access: yes, 2013
Western blot analysis of total AKT (tAKT), phospho AKT (pAKT) and ACTB of transplanted lungs derived from animals that were either treated with Deguelin or without (control).
Bertram Scheller (318724)   +8 more
core   +1 more source

Biosynthesis and Characterization of Ag3PO4/SnO2 Nanocomposites for Effective Photocatalytic Degradation of Rhodamine B and Biological Applications

open access: yesJournal of Nanotechnology, Volume 2025, Issue 1, 2025.
The current investigation focuses on the photocatalytic degradation and biological applications of M. sericea leaf extract‐mediated Ag3PO4/SnO2 nanocomposites (NCs). The synthesized nanomaterials were characterized through various characterization techniques to determine their structural and optical properties.
Vrushali Manoj Hadkar   +3 more
wiley   +1 more source

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