Results 61 to 70 of about 1,616 (183)
Medicinal Research Reviews, Volume 45, Issue 6, Page 1850-1882, November 2025.ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro +5 more
wiley +1 more source
Pharmacological basis and new insights of deguelin concerning its anticancer effects
Pharmacological Research, 2021 Deguelin is a rotenoid of the flavonoid family, which can be extracted from Lonchocarpus, Derris, or Tephrosia. It possesses the inhibition of cancer cell proliferation by inducing apoptosis through regulating the phosphoinositide 3-kinase/protein kinase B (PI3K/Akt) signaling pathway, the NF-κB signaling pathway, the Wnt signaling pathway, the ...
Zhu Yue, Lin +4 more
openaire +2 more sources
Pengendalian Lalat Pengorok Daun pada Tanaman Kentang Menggunakan Pestisida Biorasional Dirotasi dengan Pestisida Sintetik secara Bergiliran [PDF]
, 2006 . Percobaan lapang telah dikerjakan di kebun percobaan Margahayu (elevasi 1250 m dpl.), Lembang, Bandung, Jawa Barat dari bulan Agustus sampai November 2002, dengan tujuan mencari metode pengendalian alternatif terhadap lalat pengorok daun Liriomyza ...
Suryaningsih, E. (Euis)
core +2 more sources
Journal of Nanotechnology, Volume 2025, Issue 1, 2025.The current investigation focuses on the photocatalytic degradation and biological applications of M. sericea leaf extract‐mediated Ag3PO4/SnO2 nanocomposites (NCs). The synthesized nanomaterials were characterized through various characterization techniques to determine their structural and optical properties.
Vrushali Manoj Hadkar +3 more
wiley +1 more source
Cancer Cell International, 2021 Background Morphine, a µ-opioid receptor (MOR) agonist, has been shown to be related to the activity of cancer cells, and a higher morphine dosage reduces the survival time of patients with lung cancer.
Xingyun Liu +6 more
doaj +1 more source
Promoting vascular repair in the retina: can stem/progenitor cells help? [PDF]
, 2016 Since its first epidemic in the 1940s, retinopathy of prematurity (ROP) has been a challenging illness in neonatology. Higher than physiological oxygen levels impede the development of the immature retinal neuropil and vasculature.
Calzi, Sergio Li +4 more
core +2 more sources
Health Science Reports, Volume 7, Issue 12, December 2024.ABSTRACT Background and Aims The biological function of lysosomes has been increasingly appreciated in cancer. However, the relationship between lysosome and lung adenocarcinoma (LUAD) was not well understood. In this study, a lysosome‐related signature was developed for LUAD risk stratification and prognosis prediction.
Wei Ye +4 more
wiley +1 more source
PI3K/Akt pathway: a potential therapeutic target for chronic pain [PDF]
, 2017 Chronic pain is among the most disabling and costly disorders, with prevalence ranging from 10% to 55%. However, current therapeutic strategies for chronic pain are unsatisfactory due to our poor understanding of its mechanisms.
Chen, Shu-Ping +8 more
core +1 more source
Deguelin promotes apoptosis and inhibits angiogenesis of gastric cancer
Oncology Reports, 2010 Gastric cancer is often diagnosed in locally advanced or metastatic stages, which preludes a poor prognosis. As only 10% of patients with advanced gastric cancer treated with chemotherapy survive 2 years, new approaches for preventing and controlling the disease are required. We therefore, assessed in gastric cancer cells the chemotherapeutic potential
Hyunseung, Lee +3 more
openaire +3 more sources
Inhibition of Autophagy by Deguelin Sensitizes Pancreatic Cancer Cells to Doxorubicin [PDF]
International Journal of Molecular Sciences, 2016 Pancreatic cancer is the fourth most common cause of cancer mortality worldwide. Furthermore, patients with pancreatic cancer experience limited benefit from current chemotherapeutic approaches because of drug resistance. Therefore, an effective therapeutic strategy for patients with pancreatic cancer is urgently required.
Xu, Xiao-Dong +12 more
openaire +2 more sources