Results 41 to 50 of about 6,220 (165)

Chronic Low‐Dose Unsymmetrical Dimethylhydrazine Exposure in Rats: Multiorgan Mechanisms and Biomarker Identification

Journal of Applied Toxicology, EarlyView.
ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu, Bing Liu, Keli Wang, Xiaoyu Wang, Zhen Sun, Xiaojuan Pan, Zengming Zhao   +6 more
wiley   +1 more source

Lentinula edodes Grown on Di(2-ethylhexyl) Phthalate-Containing Media: Mycelial Growth and Enzyme Activities

BioResources, 2015
Di(2-ethylhexyl) phthalate (DEHP) is a plasticizer that is widely used to soften plastic products. It is an endocrine-disrupting compound, widely considered an environmental contaminant that is difficult to remove or degrade. The radial growth rate (ur),
Ángel González-Márquez, Miriam Ahuactzin-Pérez, Carmen Sánchez   +2 more
doaj   +1 more source

Combined effect of co-exposure to di (2-ethylhexyl) phthalates and 50-Hz magnetic-fields on promoting human amniotic cells proliferation

Ecotoxicology and Environmental Safety, 2021
Di (2-ethylhexyl) phthalate (DEHP) and extremely low-frequency electromagnetic fields (ELF-EMFs) exist far and wide in our surroundings. Studies have reported that both of DEHP and ELF-EMFs could promote cell proliferation which is related with adverse ...
Liangjing Chen, Anfang Ye, Xiaochen Liu, Jingchun Lu, Qixin Xie, Yixin Guo, Wenjun Sun   +6 more
doaj   +1 more source

Evaluating the Endocrine‐Disrupting and Oxidative Stress Potential of a 50‐Component Human‐Relevant Complex Chemical Mixture Using In Vitro Tests

Journal of Applied Toxicology, EarlyView.
ABSTRACT Humans are chronically exposed to mixtures of environmental contaminants. Exposure to endocrine‐disrupting chemicals (EDCs) contributes to increased health impairment observed globally. This study aimed to evaluate the endocrine‐disruptive and oxidative stress potential of a human‐relevant, complex chemical mixture in vitro.
Josefin Engelhardt, Nathalie Struwe, Annika Jansson, Vesna Munic Kos, Maria Larsson, Jana M. Weiss   +5 more
wiley   +1 more source

A Mechanochemical Kolbe–Schmitt Reaction: Catechol Carboxylation Provides Building Blocks for Renewable Plasticizers

Angewandte Chemie, Volume 138, Issue 12, 16 March 2026.
A mechanochemical Kolbe–Schmitt reaction of disodium catecholate enables the synthesis of mono‐ and dicarboxylated catechols at low temperature and CO2 pressure. Directly derivatizing the resulting carboxylic acid and phenolic moieties in the obtained mixture provides plasticizer blends with efficiencies competitive to commercial benchmarks.
Dries De Vos, Victoria S. Pfennig, Arno Goddé, Robby Vroemans, Tobias Krückel, Nicole Marcinkowska, Ettore Bartalucci, Thomas Wiegand, Carsten Bolm, Bert U. W. Maes   +9 more
wiley   +2 more sources

In vitro assessment of di(2-ethylhexyl) phthalate effect on epididymal sperm quality in dromedary camels

Open Veterinary Journal
Background: Di(2-ethylhexyl) phthalate (DEHP), a commonly used plasticizer and endocrine disruptor, has been implicated in various reproductive disorders in farm animals.
Dina E. M. Rashad, Ahmed S. A. Sosa, Seham F. Shehata, Karima Gh. M. Mahmoud, Mohamed M. M. El-Sokary   +4 more
doaj   +1 more source

The synergistic toxicity effect of di(2-ethylhexyl)phthalate and plant growth disturbs the structure and function of soil microbes in the rhizosphere

Environment International, 2022
Di-(2-ethylhexyl) phthalate (DEHP) is a dominant phthalic acid ester in the environment and commonly occurs at high concentration in agricultural soils. Its influence on the soil microbial community has been widely reported, while research related to its
Longfei Jiang, Xiaoping Zhu, Chunling Luo, Dandan Song, Mengke Song   +4 more
doaj   +1 more source

Mutagenic/carcinogenic potential of DEHP and MEHP. [PDF]

Environmental Health Perspectives, 1982
The mutagenic/carcinogenic activities of DEHP and MEHP were studied in bacteria and mammalian cells. MEHP but not DEHP exerted a dose-dependent DNA damaging effect to B. subtilis in Rec-assay. DEHP and MEHP showed mutagenic activities to S. typhimurium TA-100, with and without S-9 mix, respectively. MEHP produced not only the mutation in E. coli WP2B/r
I, Tomita, Y, Nakamura, N, Aoki, N, Inui
openaire   +3 more sources

Comparison of Recycled Polypropylene Sourced From Food and Nonfood Applications for Direct Food Contact Use

Packaging Technology and Science, EarlyView.
Utilisation of postconsumer recycled (PCR) plastic for food contact has safety concerns due to the potential presence of unapproved intentionally/non‐intentionally added substances, which can pose health and environmental risks if not removed during recycling.
Khairun Tumu, Keith Vorst, Greg Curtzwiler   +2 more
wiley   +1 more source

Nanomaterials' Multigenerational Effects by Single and Joint Exposure in Non‐mammalian Models

Environmental Toxicology, EarlyView.
ABSTRACT Nanotoxicology has mainly focused on single‐generation studies, leaving multigenerational toxicity underexplored. Having animal welfare recently gained importance, we aimed to provide the state‐of‐the‐art of knowledge about multigenerational effects in non‐mammalian models in the case of nanomaterials (NM) single and joint exposure to other ...
Andy Joel Taipe Huisa, Analía Ale, Azael Francisco Silva Neto, Lorena De Mendonça Lucena, Marcelo Estrella Josende, Milena Ferreira de Lima, Rhayanny Kethylly Pereira Santos, Martín Federico Desimone, Priscila Gubert, José María Monserrat   +9 more
wiley   +1 more source