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Recent Advances on Biological Activities and Structural Modifications of Dehydroabietic Acid [PDF]

open access: yesToxins, 2022
Dehydroabietic acid is a tricyclic diterpenoid resin acid isolated from rosin. Dehydroabietic acid and its derivatives showed lots of medical and agricultural bioactivities, such as anticancer, antibacterial, antiviral, antiulcer, insecticidal, and ...
Meng Hao   +6 more
doaj   +5 more sources

Effects of dehydroabietic acid on nontarget lipidomics and proteomics of HepG2 [PDF]

open access: yesFrontiers in Pharmacology, 2022
Objective: Studies of the effects of dehydroabietic acid on the multiomics of HepG2 hepatoma carcinoma cells are currently lacking. In this study, the molecular mechanism of the influence of dehydroabietic acid on HepG2 cells was disclosed by studying ...
Zhikai Xiahou, Jun Han, Jun Han
doaj   +5 more sources

Experimental Determination and Computational Prediction of Dehydroabietic Acid Solubility in (−)-α-Pinene + (−)-β-Caryophyllene + P-Cymene System [PDF]

open access: yesMolecules, 2022
The solubility of dehydroabietic acid in (−)-α-pinene, p-cymene, (−)-β-caryophyllene, (−)-α-pinene + p-cymene, (−)-β-caryophyllene + p-cymene and (−)-α-pinene + (−)-β-caryophyllene were determined using the laser monitoring method at atmospheric pressure.
Yanmin Qin   +6 more
doaj   +3 more sources

Synthesis and Antiproliferative Activity of Novel Dehydroabietic Acid-Chalcone Hybrids [PDF]

open access: yesMolecules, 2022
Dehydroabietic Acid (DHA, 1) derivatives are known for their antiproliferative properties, among others. In the context of this work, DHA was initially modified to two key intermediates bearing a C18 methyl ester, a phenol moiety at C12, and an acetyl or
Sophia Grigoropoulou   +6 more
doaj   +3 more sources

Dehydroabietic Acid Is a Novel Survivin Inhibitor for Gastric Cancer [PDF]

open access: yesPlants, 2021
Gastric cancer is a malignant tumor with a high incidence and mortality rate worldwide. Nevertheless, anticancer drugs that can be used for gastric cancer treatment are limited.
Won-Jin Kim   +4 more
doaj   +3 more sources

Dehydroabietic Acid Microencapsulation Potential as Biofilm-Mediated Infections Treatment [PDF]

open access: yesPharmaceutics, 2021
The antimicrobial activity of dehydroabietic acid (DHA) for its use as an antibiofilm agent was tested in this work. DHA was assayed against a collection of Gram-positive, Gram-negative sensitive and resistant bacteria and yeasts through the minimum ...
Iris Neto   +6 more
doaj   +3 more sources

The Antifungal Activity and Mechanism of Dehydroabietic Acid Against Alternaria alternata Causing Poplar Leaf Spot [PDF]

open access: yesJournal of Fungi
Dehydroabietic acid (DHA) is a secondary metabolite isolated from rosin, which has certain antifungal activity, but its inhibitory effects against Alternaria alternata are unclear.
Yun-Ze Chen   +5 more
doaj   +3 more sources

Semisynthetic Abietic and Dehydroabietic Acid Derivatives and Triptoquinone Epimers Interfere with LPS-Triggered Activation of Dendritic Cells [PDF]

open access: yesMolecules, 2022
Abietic acid (AA), dehydroabietic acid (DHA) and triptoquinones (TQs) are bioactive abietane-type diterpenoids, which are present in many edible vegetables and medicinal herbs with health-promoting properties. Evidence suggests that beneficial effects of
Jelver A. Sierra   +5 more
doaj   +3 more sources

Antiprotozoal Activity of Triazole Derivatives of Dehydroabietic Acid and Oleanolic Acid [PDF]

open access: yesMolecules, 2017
Tropical parasitic diseases such as Chagas disease and leishmaniasis are considered a major public health problem affecting hundreds of millions of people worldwide.
Mariano Walter Pertino   +5 more
doaj   +5 more sources

Facile Construction of Bio-Based Supramolecular Hydrogels from Dehydroabietic Acid with a Tricyclic Hydrophenanthrene Skeleton and Stabilized Gel Emulsions [PDF]

open access: yesMolecules, 2021
Supramolecular hydrogels have attracted great attention due to their special properties. In this research, bio-based supramolecular hydrogels were conveniently constructed by heating and ultrasounding two components of dehydroabietic acid with a rigid ...
Caiyun Lin   +4 more
doaj   +3 more sources

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