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Recent Advances on Biological Activities and Structural Modifications of Dehydroabietic Acid [PDF]

open access: yesToxins, 2022
Dehydroabietic acid is a tricyclic diterpenoid resin acid isolated from rosin. Dehydroabietic acid and its derivatives showed lots of medical and agricultural bioactivities, such as anticancer, antibacterial, antiviral, antiulcer, insecticidal, and ...
Meng Hao   +6 more
doaj   +6 more sources

Antiprotozoal Activity of Triazole Derivatives of Dehydroabietic Acid and Oleanolic Acid [PDF]

open access: yesMolecules, 2017
Tropical parasitic diseases such as Chagas disease and leishmaniasis are considered a major public health problem affecting hundreds of millions of people worldwide.
Mariano Walter Pertino   +5 more
doaj   +7 more sources

Experimental Determination and Computational Prediction of Dehydroabietic Acid Solubility in (−)-α-Pinene + (−)-β-Caryophyllene + P-Cymene System [PDF]

open access: yesMolecules, 2022
The solubility of dehydroabietic acid in (−)-α-pinene, p-cymene, (−)-β-caryophyllene, (−)-α-pinene + p-cymene, (−)-β-caryophyllene + p-cymene and (−)-α-pinene + (−)-β-caryophyllene were determined using the laser monitoring method at atmospheric pressure.
Yanmin Qin   +6 more
doaj   +4 more sources

Effects of dehydroabietic acid on nontarget lipidomics and proteomics of HepG2 [PDF]

open access: yesFrontiers in Pharmacology, 2022
Objective: Studies of the effects of dehydroabietic acid on the multiomics of HepG2 hepatoma carcinoma cells are currently lacking. In this study, the molecular mechanism of the influence of dehydroabietic acid on HepG2 cells was disclosed by studying ...
Zhikai Xiahou, Jun Han, Jun Han
doaj   +4 more sources

Dehydroabietic Acid Is a Novel Survivin Inhibitor for Gastric Cancer [PDF]

open access: yesPlants, 2021
Gastric cancer is a malignant tumor with a high incidence and mortality rate worldwide. Nevertheless, anticancer drugs that can be used for gastric cancer treatment are limited.
Won-Jin Kim   +4 more
doaj   +4 more sources

Synthesis and Antiproliferative Evaluation of Novel Hybrids of Dehydroabietic Acid Bearing 1,2,3-Triazole Moiety [PDF]

open access: yesMolecules, 2019
To discover novel potent cytotoxic diterpenoids, a series of hybrids of dehydroabietic acid containing 1,2,3-triazole moiety were designed and synthesized.
Fang-Yao Li   +8 more
doaj   +4 more sources

Synthesis and Antiproliferative Activity of Novel Dehydroabietic Acid-Chalcone Hybrids [PDF]

open access: yesMolecules, 2022
Dehydroabietic Acid (DHA, 1) derivatives are known for their antiproliferative properties, among others. In the context of this work, DHA was initially modified to two key intermediates bearing a C18 methyl ester, a phenol moiety at C12, and an acetyl or
Sophia Grigoropoulou   +6 more
doaj   +4 more sources

Dehydroabietic Acid Microencapsulation Potential as Biofilm-Mediated Infections Treatment [PDF]

open access: yesPharmaceutics, 2021
The antimicrobial activity of dehydroabietic acid (DHA) for its use as an antibiofilm agent was tested in this work. DHA was assayed against a collection of Gram-positive, Gram-negative sensitive and resistant bacteria and yeasts through the minimum ...
Iris Neto   +6 more
doaj   +5 more sources

Development of indirect competitive ELISA for determination of dehydroabietic acid in duck skin and comparison with the HPLC method [PDF]

open access: yesPoultry Science, 2020
Defeathering with rosin results in rosin residue in duck skin, which may present as potential risk to human health. Dehydroabietic acid (DHAA) is a major component of rosin.
Xinyuan Qiu   +6 more
doaj   +2 more sources

Semisynthetic Abietic and Dehydroabietic Acid Derivatives and Triptoquinone Epimers Interfere with LPS-Triggered Activation of Dendritic Cells [PDF]

open access: yesMolecules, 2022
Abietic acid (AA), dehydroabietic acid (DHA) and triptoquinones (TQs) are bioactive abietane-type diterpenoids, which are present in many edible vegetables and medicinal herbs with health-promoting properties. Evidence suggests that beneficial effects of
Jelver A. Sierra   +5 more
doaj   +2 more sources

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