Synthesis and anti-inflammatory activity of novel 1,2,3-triazole- derivatives from 7-Oxodehydroabietic acid [PDF]
BMC ChemistryDehydroabietic acid (DHA) is a naturally occurring diterpene with relevant biological activities. 7-Oxodehydroabietic acid as a highly oxidized state derivative from Dehydroabietic acid (DHA) showing good activities.
Yong-Feng Lv +5 more
doaj +2 more sources
Synthesis and biological evaluation of novel N-(piperazin-1-yl)alkyl-1H-dibenzo[a,c]carbazole derivatives of dehydroabietic acid as potential MEK inhibitors [PDF]
Journal of Enzyme Inhibition and Medicinal Chemistry, 2019 In this paper, a series of novel 1H-dibenzo[a,c]carbazole derivatives of dehydroabietic acid bearing different N-(piperazin-1-yl)alkyl side chains were designed, synthesised and evaluated for their in vitro anticancer activities against three human ...
Hao Chen +5 more
doaj +2 more sources
Dehydroabietic Acid Isolated from Commiphora opobalsamum Causes Endothelium-Dependent Relaxation of Pulmonary Artery via PI3K/Akt-eNOS Signaling Pathway [PDF]
Molecules, 2014 Commiphora opobalsamum is a Traditional Chinese Medicine used to treat traumatic injury, mainly by relaxing blood vessels. In this study, two diterpenes, dehydroabietic acid (DA) and sandaracopimaric acid (SA) were obtained from it by a bioassay-guided ...
Wenyan Gao +8 more
doaj +2 more sources
Anti-Virulence Strategy of Novel Dehydroabietic Acid Derivatives: Design, Synthesis, and Antibacterial Evaluation. [PDF]
Int J Mol Sci, 2023 Anti-virulence strategies are attractive and interesting strategies for controlling bacterial diseases because virulence factors are fundamental to the infection process of numerous serious phytopathogenics.
Qi P +9 more
europepmc +2 more sources
Electrochemical Oxidation of Abietic and Dehydroabietic Acids for Sustainable Access to C-7 and C-15 Oxygenated Abietanes. [PDF]
ChemSusChemBatch and flow electrochemical methods enable direct C‐7 oxidation of abietic and dehydroabietic acids from colophony or their methyl derivatives to the corresponding ketones, while a mediated protocol enables additional C‐15 oxygenation, providing sustainable and selective routes to diversified abietane derivatives.
Martins IS, Afonso CAM, Coelho JAS.
europepmc +2 more sources
Asian Pacific Journal of Tropical Biomedicine, 2022 Objective: To explore the mechanism of drug resistance in acute lymphoblastic leukemia and the anti-tumor effect of combination therapy of dehydroabietic acid and vincristine against acute lymphoblastic leukemia cells.
Li-Li Shen +3 more
doaj +1 more source
Synthesis and Biological Evaluation of Novel Dehydroabietic Acid-Oxazolidinone Hybrids for Antitumor Properties. [PDF]
Int J Mol Sci, 2018 Novel representatives of the important group of biologically-active, dehydroabietic acid-bearing oxazolidinone moiety were synthesized to explore more efficacious and less toxic antitumor agents.
Wang X +7 more
europepmc +2 more sources
Table1_Effects of dehydroabietic acid on nontarget lipidomics and proteomics of HepG2.XLSX [PDF]
, 2022 Objective: Studies of the effects of dehydroabietic acid on the multiomics of HepG2 hepatoma carcinoma cells are currently lacking. In this study, the molecular mechanism of the influence of dehydroabietic acid on HepG2 cells was disclosed by studying ...
Jun Han (231645) +1 more
core +1 more source
Ice core records of levoglucosan and dehydroabietic and vanillic acids from Aurora Peak in Alaska since the 1660s: a proxy signal of biomass-burning activities in the North Pacific Rim [PDF]
Atmospheric Chemistry and Physics, 2020 A 180 m long (343 years) ice core was drilled in the saddle of Aurora Peak in Alaska (63.52∘ N, 146.54∘ W; elevation: 2825 m) and studied for biomass-burning tracers.
A. Pokhrel +11 more
doaj +1 more source
Table3_Effects of dehydroabietic acid on nontarget lipidomics and proteomics of HepG2.XLSX [PDF]
, 2022 Objective: Studies of the effects of dehydroabietic acid on the multiomics of HepG2 hepatoma carcinoma cells are currently lacking. In this study, the molecular mechanism of the influence of dehydroabietic acid on HepG2 cells was disclosed by studying ...
Jun Han (231645) +1 more
core +1 more source