Synthesis and Antiproliferative Activity of Some Novel Triazole Derivatives from Dehydroabietic Acid [PDF]
Dehydroabietic acid (DHA) is a naturally occurring diterpene with different and relevant biological activities. Previous studies have shown that some DHA derivatives display antiproliferative activity.
Mariano Walter Pertino +3 more
doaj +4 more sources
The title compound [systematic name: (1R,4aS,10aR)-7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylic acid], C20H28O2, has been isolated from disproportionated rosin which is obtained by isomerizing gum rosin with a Pd-C ...
Xiao-Ping Rao +2 more
doaj +4 more sources
Gastroprotective and cytotoxic effect of dehydroabietic acid derivatives [PDF]
Dehydroabietic acid derivatives have been reported to display antisecretory and antipepsin effect in animal models. Some 19 dehydroabietic acid diterpenes were prepared and assessed for gastroprotective activity in the HCl/EtOH-induced gastric lesions in mice as well as for cytotoxicity in human lung fibroblasts (MRC-5) and human epithelial gastric ...
Guillermo Schmeda-Hirschmann +2 more
exaly +6 more sources
Dehydroabietic Acid Suppresses Inflammatory Response Via Suppression of Src-, Syk-, and TAK1-Mediated Pathways. [PDF]
Dehydroabietic acid (DAA) is a naturally occurring diterpene resin acid derived from coniferous plants such as Pinus and Picea. Various bioactive effects of DAA have been studied including antibacterial, antifungal, and anticancer activities.
Kim E +9 more
europepmc +4 more sources
Facile Construction of Bio-Based Supramolecular Hydrogels from Dehydroabietic Acid with a Tricyclic Hydrophenanthrene Skeleton and Stabilized Gel Emulsions [PDF]
Supramolecular hydrogels have attracted great attention due to their special properties. In this research, bio-based supramolecular hydrogels were conveniently constructed by heating and ultrasounding two components of dehydroabietic acid with a rigid ...
Caiyun Lin +4 more
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One-Pot Synthesis of Abietane-Type Hydroxamic Acids: Process Optimization and Mechanistic Insights [PDF]
The synthesis of hydroxamic acids from sterically hindered substrates, such as abietane-type resin acids, remains a synthetic challenge due to the congestion of the tricyclic skeleton.
William E. Mendoza-Hernández +3 more
doaj +2 more sources
Synthesis and bulk polymerization kinetics of monomer dehydroabietic acid-(2-acryloyloxy-ethoxy)-ethyl ester [PDF]
A bulk polymerization monomer dehydro- abietic acid-(2-acryloyloxy-ethoxy)-ethyl ester (DHA-DG-AC) was synthesized from dehydroabietic acid (DHA). The chemical structure of DHA-DG-AC was characterized by 1H NMR, 13C NMR, MS and FT-IR. The kinetics of the
Haibo ZHANG,Yanping YANG,He LIU,Jie SONG,Shibin SHANG,Zhanqian SONG
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Synthesis and Evaluation of New Quinoxaline Derivatives of Dehydroabietic Acid as Potential Antitumor Agents [PDF]
A series of new quinoxaline derivatives of dehydroabietic acid (DAA) were designed and synthesized as potential antitumor agents. Their structures were characterized by IR, 1H-NMR, 13C-NMR, and MS spectra and elemental analyses.
Wen Gu +7 more
doaj +2 more sources
The Antifungal Activity and Mechanism of Dehydroabietic Acid Against Alternaria alternata Causing Poplar Leaf Spot [PDF]
Dehydroabietic acid (DHA) is a secondary metabolite isolated from rosin, which has certain antifungal activity, but its inhibitory effects against Alternaria alternata are unclear.
Yun-Ze Chen +5 more
doaj +2 more sources
First Evidence of Dehydroabietic Acid Production by a Marine Phototrophic Gammaproteobacterium, the Purple Sulfur Bacterium Allochromatium vinosum MT86 [PDF]
The production of secondary metabolites by a new isolate of the purple sulfur bacterium Allochromatium vinosum, which had shown antibiotic activities during a preliminary study, revealed the production of several metabolites.
Johannes F. Imhoff +4 more
doaj +2 more sources

