Results 81 to 90 of about 60,390 (275)

A Single Centre Study to Describe the Changes in Serum Testosterone Concentration Following Application of Testosterone Gel in Post‐Menopausal Women With Hypoactive Sexual Desire Disorder (HSSD) Already Receiving This as Part of Usual Care in Conjunction With Oestrogen‐Containing Hormone Replacement Treatment (HRT)

Clinical Endocrinology, EarlyView.
ABSTRACT Introduction Hypoactive Sexual Desire Disorder (HSDD) is characterized by a long‐term decrease in sexual desire (low‐libido) causing personal distress. HSDD predominantly affects post‐menopausal women or following oophorectomy. Despite the clear indication that testosterone action could overcome the symptoms of HSDD by elevating testosterone ...
Adrian Heald, Yasitha Illangasekera, Hassan Rehman, Mark Livingston, Anne Keen, Rupinder Kochhar, Nicholas Panay, Joanna Borzomato, Mathilde Mordaunt, Peter Taylor, Geoff Hackett   +10 more
wiley   +1 more source

Dehydroepiandrosterone modulates oxidative DNA damage in pancreatic cancer: A case–control study

JGH Open, 2021
Background and Aim Dehydroepiandrosterone (DHEA) has a protective role against several types of cancer, although its mechanisms of action are still unknown, it may be related to the antioxidant effect of DHEA.
Hamid Reza Fazli, Ashraf Mohamadkhani, Hamed Reza Godarzi, Akram Pourshams, Mojtaba Jafari Nia   +4 more
doaj   +1 more source

Apparent Bilateral Aldosterone Suppression During Adrenal Vein Sampling: An Artefact of the Liaison Chemiluminescence Immunoassay and Other Causes Revealed by Comparisons With Another Commercial Immunoassay and Mass Spectrometry

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Subtyping of primary aldosteronism usually requires adrenal vein sampling (AVS). Interpretation can be compromised by apparent bilateral aldosterone suppression (ABAS), which we hypothesised reflects an artefact of the Liaison immunoassay of aldosterone.
Christina Pamporaki, Carmina T. Fuss, Ralph Kickuth, Lydia Kürzinger, Mirko Peitzsch, Sybille Fuld, Manuel Schulze, Jun Yang, Martin Reincke, Sven Gruber, Felix Beuschlein, Jacques W. M. Lenders, Graeme Eisenhofer   +12 more
wiley   +1 more source

Endocrinologic Control of Men's Sexual Desire and Arousal/Erection [PDF]

, 2016
Several hormones and neurotransmitters orchestrate men's sexual response, including the appetitive (sexual desire) and consummative (arousal and penile erection) phases.
Aversa, Antonio, Burnett, Arthur L., Corona, Giovanni, Isidori, Andrea, Maggi, Mario   +4 more
core   +1 more source

A Study of the Association between Dehydroepiandrosterone and Frailty in Elderly

Journal of the Indian Academy of Geriatrics, 2018
Objective: To determine the association between dehydroepiandrosterone and frailty in the elderly. Methods: In this cross-sectional analytical study, older people aged 65 and above attending the geriatric outpatient and inpatient services were screened ...
P Aravind Babu, S Deepa
doaj  

Design and Synthesis of Novel Dehydroepiandrosterone Analogues as Potent Antiproliferative Agents

Molecules, 2018
The aim of the present study was to determine the cytotoxic effects of a series of novel dehydroepiandrosterone derivatives containing triazole at the C16 position on human cancer cells. The cancer cells used in the present study were A549, Hela, HepG-2,
Xing Huang, Qing-Kun Shen, Hong-Jian Zhang, Jia-Li Li, Yu-Shun Tian, Zhe-Shan Quan   +5 more
doaj   +1 more source

Inositol and Berberine Synergistically Reprogram Endocrine and Ovarian Metabolism in Polycystic Ovary Syndrome

Cell Proliferation, EarlyView.
In a DHEA+HFD‐induced mouse model, Ins/BBR alleviated mitochondrial defects and broadly reprogrammed metabolic landscape in granulosa cells, in specific, restoring nucleotide pools and amino acid turnover, and preventing abnormal long‐chain fatty acid accumulation.
Juan Ge, Chenxiang Zhang, Yilong Zhao, Haiyang Zhao, Shuai Zhu, Tao Tang, Guorui Zhang, Qiang Wang, Hui Wang   +8 more
wiley   +1 more source

The role of hypothalamus-pituitary-adrenal (HPA)-like axis in inflammatory pilosebaceous disorders [PDF]

, 2020
Skin is the largest peripheral endocrine organ and functions as a hormone target and endocrine gland. A cutaneous hypothalamus-pituitary-adrenal (HPA)-like axis enables the skin to respond to stress and regulates its steroidogenic activity.
Clark, Ashley K, Saric-Bosanac, Suzana, Shi, Vivian Y, Sivamani, Raja K   +3 more
core  

Androgens and Hypertension in Men and Women: a Unifying View. [PDF]

, 2017
This review was designed to revaluate the androgen role on the mechanisms of hypertension and cardiovascular risks in both men and women. Sex steroids are involved in the regulation of blood pressure, but pathophysiological mechanism is not well ...
Carmina, E. 4., Gnessi, Lucio, Lanzolla, Giulia, Moretti, Costanzo, Moretti, Marta   +4 more
core   +1 more source

A Case–Control Study of the Association of Novel Androgens (11-KT and DHT), Classical Androgens (Testosterone and DHEAS), Hormones (LH, FSH, 17-OHP, Insulin, and SHBG), Insulin Resistance (HOMA-IR), and Dyslipidemia in Polycystic Ovarian Syndrome (PCOS)

Advanced Biomedical Research
Background: The measurement of androgens (testosterone and dehydroepiandrosterone sulfate (DHEAS)) remains standard for the evaluation of polycystic ovarian syndrome (PCOS) women.
Nirmal Kumar, Neera Sharma, Smita Roy, Indu Chawla, Lokesh Kumar Sharma   +4 more
doaj   +1 more source