Results 91 to 100 of about 134,253 (304)

Sunscreens - Which and what for? [PDF]

, 2005
It is well established that sun exposure is the main cause for the development of skin cancer. Chronic continuous UV radiation is believed to induce malignant melanoma, whereas intermittent high-dose UV exposure contributes to the occurrence of actinic ...
Ananthaswamy HN, Autier P, Azurdia RM, Birt DF, Bush JA, Damian DL, Darlington S, Gallagher RP, Gers-Balag H, Gil EM, Green A, Hallmans G, Hany J, Katiyar SK, Kipp C, Kricker A, Krutman J, Kunz PY, Lapidot N, Levy SB, Loeppky R, Mackie B, Mc Vean M, Mitchnik M, Montemarano AD, Noonan FP, Okereke CS, Perugini P, Petersen AB, Pinnell SR, Poh Agin P, Poon TS, Record IR, Rouabia M, Runger TM, Sayre RM, Scalia S, Schauder S, Schlumpf M, Schrader K, Schulz J, Schwarz VA, Stern RS, Tebbe B, Wamer W, Wang ZY, Wolf R, Wulf HC, Yarosh D, Zhao J   +49 more
core   +1 more source

Interleukin (IL)‐5, Eosinophils and IL‐5 Pathway Inhibitors in Eosinophilic Granulomatosis with Polyangiitis.

Arthritis &Rheumatology, Accepted Article.
Alvise Berti, Christian Pagnoux
wiley   +1 more source

RORγt‐APCs: The New Masters of Oral Tolerance

Barrier Immunity, EarlyView.
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley   +1 more source

The β integrin modulates serotonin sensitivity via NPxY motifs to regulate egg laying and mechanosensation behaviors in Caenorhabditis elegans

Developmental Dynamics, EarlyView.
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm, Daniel Dogeon Lee, Zhongqiang Qiu, Angela Haeun Choi, Meghana Kolluri, Michael J. Olsen, Lianzijun Wang, Myeongwoo Lee   +7 more
wiley   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Drug Allergy: Delayed Cutaneous Hypersensitivity Reactions to Drugs

European Medical Journal Allergy & Immunology, 2016
Drug allergies, also termed adverse drug reactions (ADRs), are a problem for individuals of all ages, from paediatric to geriatric, and in all medical settings.
Rose L. Hamm
doaj  

Mental and emotional health [PDF]

, 2012
Nowadays probably every person came across the term Psychotherapy. It seems, however, not to be so clear what psychotherapy actually means. Besides that, it seems to be not so clear, what a Psychotherapist does and how s/he can assist someone, who
Ohk, Brigitte
core  

Genetic analysis of the Replication Protein A large subunit family in Arabidopsis reveals unique and overlapping roles in DNA repair, meiosis and DNA replication [PDF]

, 2013
Replication Protein A (RPA) is a heterotrimeric protein complex that binds single-stranded DNA. In plants, multiple genes encode the three RPA subunits (RPA1, RPA2 and RPA3), including five RPA1-like genes in Arabidopsis.
Aklilu, Behailu B., Culligan, Kevin M., Soderquist, Ryan S.   +2 more
core   +5 more sources

Short‐Term Outcomes of Advanced Pneumatic Compression Device Versus Usual Care Therapy for Head and Neck Cancer‐Related Lymphedema: A Multi‐Site Randomized Clinical Trial

Head &Neck, EarlyView.
ABSTRACT Background Two‐month outcomes of advanced pneumatic compression device (APCD) and usual care (UC) in Head and Neck Cancer survivors with previously untreated lymphedema were compared. Methods Participants in this multisite, randomized clinical trial were randomized to APCD or UC.
Barbara A. Murphy, Derek K. Smith, Cristina M. Kline‐Quiroz, Katrina M. Jensen, Ammar W. Sukari, Mihir K. Bhayani, Vikas Mehta, Harry Quon, Jennifer L. Shah, Christopher D. Willey, Neal E. Dunlap, Hoon K. Lee, Joseph M. Aulino, Sheila H. Ridner   +13 more
wiley   +1 more source

Review of NSAID Hypersensitivity Reactions Based on Clinical Phenotyping

Journal of Clinical Rheumatology and Immunology
Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used for their analgesic, antipyretic, and anti-inflammatory properties. However, they are also associated with a broad spectrum of hypersensitivity reactions, ranging from mild cutaneous ...
Cheong Si Leong, Chan Choi Man, Andy Ka Chun Kan, Philip Hei Li   +3 more
doaj   +1 more source