Results 101 to 110 of about 2,087,247 (387)

Biomaterial Properties of Titanium in Dentistry [PDF]

, 2015
Background Among various dental materials and their successful restorative uses, titanium provides an excellent example of integrating science and technology involving multiple disciplines of dentistry including biomaterials, prosthodontics and surgical ...
Ehrensberger, Mark, Kim, Hyeongil, Monaco, Jr., Edward A., Prasad Gibson, Monica, Prasad, Soni   +4 more
core   +1 more source

Food elimination based on IgG antibodies in irritable bowel syndrome: a randomised controlled trial [PDF]

, 2004
Background: Patients with irritable bowel syndrome (IBS) often feel they have some form of dietary intolerance and frequently try exclusion diets. Tests attempting to predict food sensitivity in IBS have been disappointing but none has utilised IgG ...
Atkinson, W., Shaath, N., Sheldon, T.A., Whorwell, P.J.   +3 more
core   +3 more sources

Redefining the Skin Barrier: A Microbiome‐Integrated Multilayered Defense Model

Barrier Immunity, EarlyView.
ABSTRACT The skin constitutes a dynamic interface orchestrating a sophisticated multilayered defense system comprising physical, chemical, immune, and microbial barriers. This review synthesizes current understanding of the structural and functional integration of these barriers, emphasizing their synergistic interactions in maintaining cutaneous ...
Jingjing Xia, Mathias Hochgerner, Qingzhen Wei, Xian'ge Zhong, Jiucun Wang   +4 more
wiley   +1 more source

Lymphocyte Transformation Test (LTT) in Allergy to Benznidazole: A Promising Approach

Frontiers in Pharmacology, 2019
Benznidazole (Bzn) from the nitroimidazole family and nifurtimox from nitrofurans family, are drugs used as first and second line treatment for acute and chronic phases of Chagas disease (CD). Even though skin reactions are frequent, confirmed allergy to
M. Andreína Marques-Mejías, Rosario Cabañas, Rosario Cabañas, Rosario Cabañas, Elena Ramírez, Elena Ramírez, Javier Domínguez-Ortega, Javier Domínguez-Ortega, Ana Fiandor, Ana Fiandor, Elena Trigo, Elena Trigo, Santiago Quirce, Santiago Quirce, Teresa Bellón, Teresa Bellón   +15 more
doaj   +1 more source

DNMTs are required for delayed genome instability caused by radiation [PDF]

, 2012
This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited ...
Anderson, RM, Armstrong, CA, Iyer, P, Jones, GD, Narayanan, D, Sandhu, J, Singh, R, Talbot, CJ, Talbot, CJ, Tufarelli, C, Tufarelli, C   +10 more
core   +2 more sources

The β integrin modulates serotonin sensitivity via NPxY motifs to regulate egg laying and mechanosensation behaviors in Caenorhabditis elegans

Developmental Dynamics, EarlyView.
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm, Daniel Dogeon Lee, Zhongqiang Qiu, Angela Haeun Choi, Meghana Kolluri, Michael J. Olsen, Lianzijun Wang, Myeongwoo Lee   +7 more
wiley   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Overexpression of vascular permeability factor (VPF/VEGF) and its endothelial cell receptors in delayed hypersensitivity skin reactions.

Journal of Immunology, 1995
Delayed hypersensitivity (DH) is a T cell-mediated form of immune response characterized by a predominantly perivascular, mononuclear cell infiltrate. The venules in DH reactions are hyperpermeable to plasma proteins, leading to extravasation of plasma ...
L. Brown, Suzanne M. Olbricht, B. Berse, Robert W. Jackman, G. Matsueda, K. Tognazzi, E. Manseau, Harold F. Dvorak, L. Water   +8 more
semanticscholar   +1 more source

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

Ibrain, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

Drug Allergy: Delayed Cutaneous Hypersensitivity Reactions to Drugs

European Medical Journal Allergy & Immunology, 2016
Drug allergies, also termed adverse drug reactions (ADRs), are a problem for individuals of all ages, from paediatric to geriatric, and in all medical settings.
Rose L. Hamm
doaj