Results 61 to 70 of about 2,087,247 (387)

DELAYED HYPERSENSITIVITY [PDF]

open access: yesThe Journal of Experimental Medicine, 1957
A general method for induction of the delayed hypersensitive state directed against single protein antigens is described. The method consists of intradermal injection of minute amounts of washed immune precipitates containing the antigen in question.
Jonathan W. Uhr   +2 more
openaire   +3 more sources

Drug fever—an immune-mediated delayed type hypersensitivity reaction to Vinca alkaloids in pediatric oncology patients, possibly mediated by cysteinyl leukotrienes

open access: yesFrontiers in Allergy
BackgroundDrug hypersensitivity reactions are common in pediatric hemato-oncology patients due to multiple factors including immune compromise and pharmacological complexities. Fever can signify severe delayed-type hypersensitivity reactions such as drug
Mona I. Kidon   +12 more
doaj   +1 more source

Outcome of a de-labelling algorithm compared with results of penicillin (β-lactam) allergy testing

open access: yesAllergy, Asthma & Clinical Immunology, 2022
Background Penicillin allergy labels frequently impede guideline-directed treatment with a penicillin or other β-lactam antibiotics. Despite presumed allergy, targeted questioning may indicate a low probability of sensitization and permit reasonably safe
Philipp Schrüfer   +2 more
doaj   +1 more source

Cutaneous Reactions after COVID-19 vaccines

open access: yesVaccine Research, 2021
Cutaneous reactions reported post COVID-19 trials range from acute and immediate to delayed reactions. The suspected trigger for hypersensitivity reactions is the inactive ingredients, such as polyethylene glycol in mRNA vaccines and polysorbate 80 in ...
Alicia Wan Yan Poh, Shyh Poh Teo
doaj   +1 more source

Psychologic modulation of the human immune response to varicella zoster [PDF]

open access: yes, 1985
Psychoimmunology, the interrelationship between the brain/mind/psyche and the immune system, is now an established area of scientific research. Based on prior investigations we hypothesized that an experienced meditator could affect her delayed ...
Marmer, D. J.   +3 more
core   +1 more source

Optimization of the Nonclinical Biological Evaluation of Medical Devices Using Toxicologic Pathology Best Practices

open access: yesAdvanced Healthcare Materials, EarlyView.
Nonclinical evaluation of biological responses to implanted medical devices and combination products in animals is required to predict possible outcomes and risks in patients. This paper describes globally accepted pathology “best practices” that 1) effectively address ISO standards and current regulatory guidance for medical device development and 2 ...
Kathleen A. Funk   +6 more
wiley   +1 more source

Guinea pigs sublethally infected with aerosolized Legionella pneumophila develop humoral and cell-mediated immune responses and are protected against lethal aerosol challenge. A model for studying host defense against lung infections caused by intracellular pathogens. [PDF]

open access: yes, 1987
We have employed the guinea pig model of L. pneumophila infection, which mimics Legionnaires' disease in humans both clinically and pathologically, to study humoral and cell-mediated immune responses to L.
Breiman, RF, Horwitz, MA
core  

Potencialização do efeito supressor de componentes do Ascaris suum em camundongos deficientes em IFN-γ [PDF]

open access: yes, 2009
High molecular weight components from Ascaris suum extract suppress ovalbumin-specific immunity in mice. In IFN-γ-deficient mice, ovalbumin-specific delayed-type hypersensitivity reactions are more strongly downregulated by these suppressive ...
MACEDO, Mahasti Sahihi   +1 more
core   +2 more sources

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

open access: yesAdvanced Healthcare Materials, EarlyView.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement   +12 more
wiley   +1 more source

Hypersensitivity reaction to hyaluronic acid dermal filler after COVID-19 vaccination: A series of cases in São Paulo, Brazil

open access: yesInternational Journal of Infectious Diseases, 2022
Brazil ranked second in the world for the number of aesthetic procedures carried out in 2019. Five case reports of delayed hypersensitivity reaction to hyaluronic acid dermal filler after COVID-19 vaccination are presented in this paper.
Luciena Cegatto Martins Ortigosa   +4 more
doaj   +1 more source

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