Results 71 to 80 of about 134,253 (304)

Immersive Composition for Sensory Rehabilitation: 3D Visualisation, Surround Sound, and Synthesised Music to Provoke Catharsis and Healing [PDF]

, 2014
There is a wide range of sensory therapies using sound, music and visual stimuli. Some focus on soothing or distracting stimuli such as natural sounds or classical music as analgesic, while other approaches emphasize the active performance of producing ...
A. Cohen, A. Gabrielsson, A. Jönsson, A. Ross, A.L. Gerlach, D. Austin, E. Altenmuller, M.J. Roy, S. Goodman, T. Oohashi   +9 more
core   +1 more source

Altered Auditory Maturation in Fragile X Syndrome and Its Involvement in Audiogenic Seizure Susceptibility

Autism Research, EarlyView.
ABSTRACT Auditory hypersensitivity is a prominent symptom in Fragile X syndrome (FXS), the most prevalent monogenic cause of autism and intellectual disability. FXS arises through the loss of the protein encoded by the FMR1 (Fragile X Messenger Ribonucleoprotein 1) gene, FMRP, required for normal neural circuit excitability.
Dorit Möhrle, Demi Ma, Wenyue Xue, Jun Yan, Ning Cheng   +4 more
wiley   +1 more source

Outcome of a de-labelling algorithm compared with results of penicillin (β-lactam) allergy testing

Allergy, Asthma & Clinical Immunology, 2022
Background Penicillin allergy labels frequently impede guideline-directed treatment with a penicillin or other β-lactam antibiotics. Despite presumed allergy, targeted questioning may indicate a low probability of sensitization and permit reasonably safe
Philipp Schrüfer, Johanna Stoevesandt, Axel Trautmann   +2 more
doaj   +1 more source

Heterologous carriers in the anamnestic antihapten response [PDF]

, 1968
Anamnestic antihapten responses were obtained to trinitrophenyl (TNP) when rabbits sensitized to trinitrophenyl-hemocyanin (TNP-KLH) were challenged with TNP-heterologous protein conjugates.
Campbell, Dan H., Rittenberg, Marvin B.
core   +2 more sources

Adverse immunostimulation in early phase clinical trials: Key findings and recommendations based on the investigator's clinical experience

British Journal of Clinical Pharmacology, EarlyView.
Problem setting The emergence of therapeutic proteins has coincided with an increase of acute adverse immunostimulation (AIS). AIS has occured in clinical trials despite compliance with regulatory guidelines on preclinical evaluation and its incidence is anticipated to increase even further.
Juliette A. van den Noort, Marella C. E. van Ruissen, Lisanne C. A. Smidt, Naomi B. Klarenbeek, Philip H. K. Kremer, Manon A. A. Jansen, Jacobus Burggraaf, Joop M. A. van Gerven, Matthijs Moerland   +8 more
wiley   +1 more source

A novel outpatient desensitization protocol for recombinant human erythropoietin allergy in a pediatric patient

Allergy, Asthma & Clinical Immunology, 2018
Background Recombinant human erythropoietin, such as epoetin alfa and darbepoetin alfa, is an important therapy for anemia due to chronic renal failure. Allergy to recombinant human erythropoietin and the need for desensitization are rare.
Jaime S. Rosa, Van B. Vuong, Orly Haskin, Anne Y. Liu   +3 more
doaj   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Mango Dermatitis After Urushiol Sensitization

Clinical Practice and Cases in Emergency Medicine, 2019
Prior exposure to poison ivy and poison oak, which are plants in the Anacardiacea family and contain high levels of urushiol, appear to be a risk factor for delayed hypersensitivity reactions to mango fruits.
Michael J. Yoo, Brandon M. Carius
doaj   +1 more source

Evaluation of allergenic properties and immunotoxicity tablet dosage form GML-1 (N-benzyl-N-methyl-1-phenylpyrrolo[1,2-a]pyrazin-3-carboxamide)

Фармакокинетика и Фармакодинамика, 2020
The study of allergenic properties and immunotoxic effects of the ready-to-use drug form of GML-1 (N-benzyl-N-methyl-1-phenylpyrrolo[1,2-a] pyrazin-3-carboxamide), compounds with high TSPO affinity and pronounced anxiolytic activity, was carried out. The
L. P. Kovalenko, K. V. Korzhova, R. V. Zhurikov, A. D. Durnev   +3 more
doaj   +1 more source

Biomaterial Properties of Titanium in Dentistry [PDF]

, 2015
Background Among various dental materials and their successful restorative uses, titanium provides an excellent example of integrating science and technology involving multiple disciplines of dentistry including biomaterials, prosthodontics and surgical ...
Ehrensberger, Mark, Kim, Hyeongil, Monaco, Jr., Edward A., Prasad Gibson, Monica, Prasad, Soni   +4 more
core   +1 more source