Druggable genome-wide Mendelian randomization analysis identifies potential treatment targets in vascular dementia. [PDF]
Lennon MJ +4 more
europepmc +1 more source
Objective sleep parameters and diurnal blood pressure in concurrent hypertension and type 2 diabetes
Abstract Background Hypertension is a primary cardiovascular complication in type 2 diabetes associated with increased morbidity and mortality. Ambulatory blood pressure monitoring (ABPM) is essential for capturing circadian BP variation, which is closely influenced by sleep. Methods Twenty patients (63.75 ± 4.44 years old, 40% female, duration of T2D:
Yan Zhao +6 more
wiley +1 more source
Staging concept for aging management: Definition, mechanism, and coping strategies
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang +6 more
wiley +1 more source
Association of the Planetary Health Diet with dementia risk and brain pathology. [PDF]
Yang R +6 more
europepmc +1 more source
Patients in intensive care units often experience lung injuries, complicated by brain problems. Advanced laboratory tools, organoids, and organs‐on‐chips facilitated the study of multiorgan interactions, help us understand the communication between the lungs and brain.
Wanyi Zhang +5 more
wiley +1 more source
The Impact of Insomnia on Dementia Risk in Hypertensive Individuals. [PDF]
Tsai PY +6 more
europepmc +1 more source
Abstract Background and aims Evidence on the causal impact and corresponding risk relationships between dimensions of alcohol consumption and health outcomes continues to evolve, with some contradictory findings across study designs. This review aimed to update current knowledge on causality and risk relationships to inform global and national ...
Sinclair Carr +5 more
wiley +1 more source
Repurposing drugs for the prevention of vascular dementia using evidence from drug target Mendelian randomization. [PDF]
Taylor-Bateman V +8 more
europepmc +1 more source
Corrigendum: Evaluation of Metformin on Cognitive Improvement in Patients With Non-dementia Vascular Cognitive Impairment and Abnormal Glucose Metabolism. [PDF]
Lin Y +7 more
europepmc +1 more source

