Results 121 to 130 of about 59,740 (225)

Dementia with lewy bodies - diagnosis and treatment

Swiss Medical Weekly, 2003
IG McKeith
doaj   +1 more source

Management of rapid eye movement sleep behavior disorder in patients with Parkinson's disease [PDF]

, 2016
Among all of the devastating effects that Parkinson’s disease (PD) has on an individual, sleep dysfunction is one that can have a profound effect on the entire family of the patient. The most potentially destructive of these sleep syndromes being that of
Jeffries, Michael
core   +1 more source

Revisiting the Association of Pesticide Exposure and Parkinson's Disease: Systematic Review and Meta‐Analysis

Environmental Toxicology, EarlyView.
ABSTRACT The association between pesticide exposure and Parkinson's disease (PD) is substantial, but heterogeneity in methodology and lack of categorization according to the type of exposure and pesticide classes in previous meta‐analyses impair the interpretation of data. This study aims to update evidence of the association between pesticide exposure
Pedro Henrique Passos da Silva, Jadson Silva Abreu, Rafael Sidônio Gibson Gomes, Hemengella Karyne Alves Oliveira, Artur F. S. Schuh, Ignacio F. Mata, Bruno Lopes Santos‐Lobato   +6 more
wiley   +1 more source

Involuntary Clozapine Treatment: A Systematic Review

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction We aimed to synthesize the information relevant for clinical practice on involuntary clozapine treatment. Methods Articles were identified with MEDLINE, Web of Sciences and PsycINFO search from inception through September 2025 (PROSPERO database registration CRD420251234475).
Hélène Verdoux, Alexis Lepetit, Peter F. J. Schulte   +2 more
wiley   +1 more source

Alzheimer's disease and mixed pathologies as a hidden contributor to fatal hypothermia: A large‐scale forensic autopsy‐based study

Brain Pathology, EarlyView.
We investigated neuropathological manifestations of hypothermia in 168 cases. Patients aged 65 years or more constituted 80% of the total cohort. Alzheimer's disease was the most common comorbidity, affecting 40% of all patients. Abstract There is a paucity of autopsy‐based studies providing detailed neuropathological characteristics of fatal ...
Shojiro Ichimata, Koji Yoshida, Ryo Tanaka   +2 more
wiley   +1 more source

Frontotemporal dementia: Clinical aspects, genetics, and neuropathology of a family with a C9ORF72 expansion in Argentina

Brain Pathology, EarlyView.
Immunohistochemistry for TDP‐43: (A)—Dentate gyrus; (B)—Temporal lobe. Abstract Frontotemporal dementia (FTD) is the second most common cause of early‐onset dementia, typically manifesting before the age of 65, with a mean onset at 58 years. FTD may encompass a spectrum of neurodegenerative disorders resulting from frontotemporal lobar degeneration ...
Karen Daniela Román, Carolina Agata Ardohain, Ezequiel I. Surace, Mónica Beatriz Mezmezian, Alejandro Levy, Alice Baez Lovera, Carlos Turizo, Marcos G. Sorbara, María M. Esnaola y Rojas, Gastón H. Graviotto, Gustavo Sevlever, Ricardo F. Allegri, Cecilia M. Serrano, Nahuel Magrath Guimet   +13 more
wiley   +1 more source

14‐3‐3σ up‐regulation in the temporal cortex associates with tau pathology and reactive astroglia in Lewy body disorders

Brain Pathology, EarlyView.
14‐3‐3 protein homeostasis is disrupted in Lewy body pathology, showing a diminution of six isotypes and overexpression of stratifin. The latter was associated with stratifin colocalization with tau pathology and reactive astrocytes. Platelets, as a peripheral biomarker source, mirrored inversely cortical 14‐3‐3 gene expression patterns in dementia ...
Laura Marsal‐García, Jorge Mena, Carol‐Ann Lao, David Adamuz, Laura Arnaldo, Cristina Carrato, Alex Menendez, Daniela Samaniego, Dolores Vilas, Lourdes Ispierto, Anna Planas, Ramiro Alvarez, Pau Pastor, Katrin Beyer   +13 more
wiley   +1 more source

Distinct regional patterns of synaptic vulnerability across hippocampal and parahippocampal subregions in Alzheimer's disease

Brain Pathology, EarlyView.
Synaptic loss in Alzheimer's disease predominantly affects the entorhinal cortex and parahippocampal gyrus. Amyloid‐β and p‐tau pathology show global associations with synaptic density but are limited in specific subregions. Instead, axonal damage associates with synaptic loss locally and in interconnected subregions.
Maud M. A. Bouwman, Irene Frigerio, Yvon Galis‐de Graaf, Wilma D. J. van de Berg, Laura E. Jonkman   +4 more
wiley   +1 more source

Delirium-onset prodromal Lewy body disease: A series of 5 cases

Clinical Parkinsonism & Related Disorders
Background: Delirium-onset prodromal Lewy body disease (LBD) has been proposed as one of the primary phenotypes of prodromal stages of LBD. The detailed clinical features and biomarker profiles of delirium-onset prodromal LBD have not been well ...
Daiki Taomoto, Yoshiyuki Nishio, Yousuke Hidaka, Hideki Kanemoto, Shun Takahashi, Manabu Ikeda   +5 more
doaj   +1 more source

General Dementia Training for the Social Care Workforce: A Systematic Review

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim The aim of this systematic review was to assess and synthesize the global evidence on existing general dementia training and education for the social care workforce. Design Mixed‐methods systematic review. Data Sources Systematic searches on five databases (PubMed, APA PsychINFO, CINAHL Plus, Scopus, Web of Science) were conducted for ...
Clarissa Giebel, Thais Caprioli, Marie Poole, Catherine Talbot, Jacqui Cannon, Kerry Hanna, Louise Robinson, Deborah Rozansky, Hilary Tetlow, Madeleine Walpert, Mark Gabbay   +10 more
wiley   +1 more source