Results 121 to 130 of about 39,993 (263)

Neuropathology of Lewy body dementia: Lewy-related pathology, α-synuclein oligomers, and comorbid pathologies

Molecular Neurodegeneration
Lewy body dementia is the second most common form of neurodegenerative dementia, following Alzheimer’s disease. This umbrella term encompasses dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD).
Hiroaki Sekiya, Tomoyasu Matsubara, Michael A. DeTure, Dennis W. Dickson   +3 more
doaj   +1 more source

Prognosis in Parkinson's Disease: An Individual Patient Data Meta‐Analysis of Six European Incidence Cohorts

Movement Disorders, EarlyView.
Abstract Background An accurate understanding of prognosis in Parkinson's disease (PD) is important for patient information provision, personalized treatment, and clinical trial design, but most previous research has been biased towards younger, healthier patients.
Angus D. Macleod, David J. McLernon, Marta Camacho, Caroline H. Williams‐Gray, Rachael A. Lawson, Alison J. Yarnall, David Bäckström, Lars Forsgren, Jodi Maple‐Grødem, Guido Alves, Ole‐Bjørn Tysnes, Carl E. Counsell, Parkinson's Incidence Cohorts Collaboration, Thomas Foltynie, Sarah L. Mason, Ruwani Wijeyekoon, Jonathan Evans, David P. Breen, Gemma Cummins, Krista Farrell, Kirsten Scott, Tom Stoker, Julia Greenland, Natalie Valle Guzman, Lucy Collins, Simon Stott, Jan Linder, Mona Edström, Jörgen Andersson, Linda Eriksson, Gun‐Marie Hariz, Magdalena Domellöf, Michaela Dreetz Gjerstad, Kenn Freddy Pedersen, Elin Bjelland Forsaa, Veslemøy Hamre Frantzen, Anita Laugaland, Johannes Lange, Karen Simonsen, Eldbjørg Fiske, Ingvild Dalen, Bernd Müller, Geir Olve Skeie, Marit Renså, Wenche Telstad, Aliaksei Labusau, Jane Kastet, Ineke HogenEsch, Marianne Kjerandsen, Liv Kari Håland, Karen Herlofson, Solgunn Ongre, Siri Bruun, David Burn, Lynn Rochester, Gordon W. Duncan, Tien K. Khoo, Kate S. M. Taylor, Robert Caslake, David J. M. McGhee, Diane Swallow, Joanne Gordon, Clare Harris, Ann Hayman, Nicola Johannesson, Hazel Forbes, Valerie Angus, Alasdair Finlayson, David Dawson, Katie Wilde, David Ritchie, Artur Wozniak, Adrian Martin   +72 more
wiley   +1 more source

Prediction of Co-Occurrence of Lewy Body Disease with Alzheimer’s Disease

Journal of Alzheimer's Disease Reports
Identifying the coexistence of Lewy body (LB) pathology with Alzheimer’s disease (AD) in clinical practice is important in the era of anti-amyloid-β antibody therapy. However, few studies have predicted the presence of comorbid LB pathology with AD using
Kenichi Hashiguchi, Ryota Kobayashi, Daichi Morioka, Shinobu Kawakatsu, Kazutaka Sakamoto, Hiroshi Matsuda, Akihito Suzuki   +6 more
doaj   +1 more source

Co‐ and Multi‐Pathologies in Parkinson's Disease: An International Parkinson and Movement Disorder Society Scientific Issues Committee Review

Movement Disorders, EarlyView.
Abstract Parkinson's disease (PD) has been historically defined as a disease of striatal dopamine deficiency secondary to degeneration of dopaminergic neurons in the substantia nigra pars compacta, related to the presence of Lewy bodies and Lewy neurites.
Michele Matarazzo, Per Borghammer, Inas Elsayed, Jennifer G. Goldman, Yue Huang, Katja Lohmann, Per Svenningsson, Lorraine V. Kalia, Daniela Berg, Jeffrey H. Kordower, the MDS Scientific Issues Committee   +10 more
wiley   +1 more source

Current strategies in the management of dementia with lewy bodies and future directions based on disease pathophysiology

Molecular Neurodegeneration
Dementia with Lewy bodies (DLB) is thought to be the second most common form of dementia after Alzheimer’s disease, and is characterised by a combination of cognitive, neuropsychiatric and motor symptoms.
Daniel Erskine, John-Paul Taylor
doaj   +1 more source

PROBABLE DEMENTIA WITH LEWY BODY

Romanian Journal of Neurology, 2017
V.A. female, 67 years, old admitted in our clinic for neurological assessment because of a parkinsonian syndrome, in association with neurocognitive disorder established in a psychiatric service. Motor disturbances and cognitive disorders are frecquently associated in Dementia with Lewy body (DLB) and in Parkinson Disease (PD). Psychiatric symptoms are
openaire   +2 more sources

Demography, diagnostics, and medication in dementia with Lewy bodies and Parkinson's disease with dementia: data from the Swedish Dementia Quality Registry (SveDem)

, 2013
Seyed-Mohammad Fereshtehnejad,1 Dorota Religa,2,3 Eric Westman,1 Dag Aarsland,2,4 Johan Lökk,1,3 Maria Eriksdotter1,3 1Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences, and Society (NVS), Karolinska Institutet, Stockholm ...
Lökk J, Westman E, D, Fereshtehnejad SM, Religa D, Aarsl, Eriksdotter M   +6 more
core  

Longitudinal testing of visual perception in dementia with Lewy bodies and Alzheimer's disease

, 2013
Visuo-perceptual abnormalities are a prominent feature in dementia with Lewy bodies (DLB) and also occur in Alzheimer's disease (AD) to a lesser extent. We studied the progression of visuo-perceptual abnormalities over a 12-month period in DLB and AD by ...
Barber, Robert, Blamire, Andrew M, Mosimann, Urs P, Wood, Joshua S, Firbank, Michael J, O'Brien, John T, Watson, Rosie   +6 more
core   +1 more source

Parkinson's disease dementia: a neural networks perspective.

, 2015
In the long-term, with progression of the illness, Parkinson's disease dementia affects up to 90% of patients with Parkinson's disease. With increasing life expectancy in western countries, Parkinson's disease dementia is set to become even more ...
Gratwicke, J, Jahanshahi, M, Foltynie, T
core  

Wearable Movement‐Tracking for Prodromal Parkinson's Disease Detection: A Cross‐Country Validation Study

Movement Disorders, EarlyView.
Abstract Background Models trained on accelerometer data have been proposed for detecting prodromal Parkinson's disease (PD). However, uncertainties in diagnosis timing in the UK Biobank (UKBB) may affect generalizability to other cohorts. Objectives The aim of the study was to evaluate the performance of previously published models for prodromal PD ...
Fabian Kahl, Ann‐Kathrin Schalkamp, Katarina Mary Gunter, Anja Ophey, Sinah Röttgen, Jamil Razzaque, Konstantin Kufer, Cynthia Sandor, Gereon R. Fink, Elke Kalbe, Walter Maetzler, Clint Hansen, Stephan M. Jonas, Michele T. Hu, Lara Marie Reimer, Michael Sommerauer   +15 more
wiley   +1 more source