Results 151 to 160 of about 59,740 (225)

Exploring heart rate variability as a biomarker for frailty: A narrative review

open access: yesEuropean Journal of Clinical Investigation, Volume 56, Issue 4, April 2026.
Frailty arises from progressive multisystem dysregulation, prompting interest in biomarkers that capture declining physiological reserve. This review positions heart rate variability (HRV) within this evolving biomarker landscape, outlining its physiological basis, analytical domains and relevance to clinical research.
Luca Tagliafico   +5 more
wiley   +1 more source

Recommendations to Improve Healthcare Service Provision for Cognitive Impairment in People With Parkinson's Disease: A Mixed Methods Study of the Lived Experience Expert Perspective

open access: yesHealth Expectations, Volume 29, Issue 2, April 2026.
ABSTRACT Background Cognitive impairment, including dementia, is one of the most important nonmotor symptoms of Parkinson's disease (PD). It lowers quality of life and impacts health and economic outcomes for individuals living with PD, their families, and society.
Deepa Sriram   +12 more
wiley   +1 more source

The Association Between Caregiver Psychosocial Factors and Depressive Symptoms in People With Dementia: A Systematic Review and Meta‐Analysis

open access: yesJournal of Advanced Nursing, Volume 82, Issue 4, Page 3906-3942, April 2026.
ABSTRACT Aims To identify and evaluate the magnitude of the association between caregiver psychosocial factors and depressive symptoms among people with dementia. Design Systematic review and meta‐analysis. Methods A systematic review with meta‐analysis used a random‐effects model to estimate the effect size.
Wenjing Ning   +3 more
wiley   +1 more source

The Effect of Deep Brain Stimulation on Sleep and Cognition in Patients With Parkinson's Disease

open access: yesJournal of Sleep Research, Volume 35, Issue 2, April 2026.
ABSTRACT Sleep–wake disturbances and cognitive decline are among the most common nonmotor symptoms of Parkinson's disease (PD). Deep brain stimulation (DBS) can successfully alleviate motor symptoms. However, the impact on sleep–wake disturbances and cognitive decline, and their interaction, is yet unclear.
Monique E. H. Valk‐Geuke   +5 more
wiley   +1 more source

Locus coeruleus alterations in dementia with Lewy bodies: A systematic review. [PDF]

open access: yesAlzheimers Dement (N Y)
Bain A   +5 more
europepmc   +1 more source

An Autopsy Case With Fragile X‐Associated Tremor/Ataxia Syndrome Presenting Intranuclear Inclusion Bodies Mainly in the Limbic System

open access: yesNeuropathology, Volume 46, Issue 2, April 2026.
ABSTRACT Fragile X‐associated tremor/ataxia syndrome (FXTAS) is a neurodegenerative disorder characterized by a late onset and slow progression caused by a premutation (55–200 CGG repeat) in the fragile X mental retardation (FMR1) gene. Here, we report the case of a Japanese patient with FXTAS which is the first case autopsied in Japan. The patient was
Ayako Shioya   +5 more
wiley   +1 more source

Metabolic brain networks in dementia with Lewy bodies: from prodromal to manifest disease stages. [PDF]

open access: yesJ Neurol Neurosurg Psychiatry
Perovnik M   +31 more
europepmc   +1 more source

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