Results 151 to 160 of about 33,878 (250)

Cognitive training and promoting a healthy lifestyle in isolated REM sleep behavior disorder: The randomized controlled trial CogTrAiL‐RBD

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION Isolated rapid eye movement (REM) sleep behavior disorder (iRBD) is a prodromal phase of Lewy body diseases and linked to a high risk for cognitive decline. Therefore, iRBD provides a suitable window for early intervention. METHODS In the monocentric randomized controlled trial “Cognitive Training & a Healthy, Active Lifestyle ...
Anja Ophey, Sinah Röttgen, Konstantin Kufer, Julia Pauquet, Daniel Scharfenberg, Philipp Armbrust, Anastasia Kammerzell, Nathalie Knopf, Sandy Kollath, Philipp Sommer, Christopher E. J. Doppler, Ezequiel Farrher, Aline Seger, N. Jon Shah, David Zopfs, Kathrin Reetz, Gereon R. Fink, Michael Sommerauer, Elke Kalbe   +18 more
wiley   +1 more source

Retraction Note: Effects of Novel Calpain Inhibitors in Transgenic Animal Model of Parkinson's disease/dementia with Lewy bodies. [PDF]

Sci Rep
Hassen GW, Kesner L, Stracher A, Shulman A, Rockenstein E, Mante M, Adame A, Overk C, Rissman RA, Masliah E.   +9 more
europepmc   +1 more source

Brain morphometry patterns in the presence of Alzheimer's disease and/or LATE neuropathologic changes

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION Alzheimer's disease neuropathologic change (ADNC) and limbic‐predominant age‐related transactive response DNA‐binding protein 43 kDa (TDP‐43) encephalopathy neuropathologic change (LATENC) are common in older adults, yet differences in brain morphometry patterns when one or both pathologies are present remain unclear.
Khalid Saifullah, Abdur Raquib Ridwan, Arnold M. Evia, Sue E. Leurgans, Maude Wagner, David A. Bennett, Julie A. Schneider, Konstantinos Arfanakis   +7 more
wiley   +1 more source

Treatment priorities from the perspectives of people with dementia with Lewy bodies: a reflexive thematic analysis. [PDF]

Front Dement
Donnelly PS, Mitchell K, McCorry NK, Boeri M, Passmore AP, Kane JPM.   +5 more
europepmc   +1 more source

The past, the present, and the future of preclinical mouse models for Alzheimer's disease and related dementias

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract Over the past decade, the Model Organism Development and Evaluation for Late‐Onset Alzheimer's Disease (MODEL‐AD) consortium has transformed preclinical Alzheimer's disease (AD) research by addressing critical limitations in traditional mouse models that failed to translate to human disease.
Adrian L. Oblak, Michael Sasner, Gregory W. Carter, Gareth R. Howell, Stacey J. Sukoff Rizzo, Karina Leal, Paul R. Territo, Bruce T. Lamb   +7 more
wiley   +1 more source

Heterogeneity of dementia with lewy bodies: Insights from clinical presentations, neuropathology, and biomarkers. [PDF]

Neurol Sci
Orso B, Bollack A, Sheikh ZH, Morbelli S, Pardini M, Farrar G.   +5 more
europepmc   +1 more source

Psychotropic medication use among community dwellers with and without Parkinson's disease – A nationwide cohort study

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2701-2710, August 2026.
Abstract Aims We studied the prevalence of psychotropic use and psychotropic polypharmacy in persons with Parkinson's disease (PD) during a 10‐year follow‐up, because longitudinal studies on this topic are scarce although non‐motor symptoms of PD are often treated with psychotropics.
Noora Nieminen, Anna‐Maija Tolppanen, Valtteri Kaasinen, Marjaana Koponen, Sirpa Hartikainen   +4 more
wiley   +1 more source

Underlying Mechanisms of GBA1 in Parkinson's Disease and Dementia with Lewy Bodies: Narrative Review. [PDF]

Genes (Basel)
Bougea A.
europepmc   +1 more source

Epigenetic Mechanisms Underlying Cognitive Dysfunction in Parkinson's Disease: Current Evidence and Future Prospects

Brain and Behavior, Volume 16, Issue 8, August 2026.
Epigenetic mechanismsincluding DNA methylation, histone modifications, and microRNA (miRNA) regulationmodulate gene expression without altering the DNA sequence and are increasingly implicated in the cognitive impairment associated with Parkinson's disease (PD). Environmental and molecular factors influence these epigenetic pathways, leading to altered
Fatemeh Hasani, Mohammad Ebrahim Kherad, Mohammad Sharifi Sarasyabi, Kimia Jazi, Ali Ashkbari, Payam Ahmadi, Hadise Heidarpour, Mahdi Masrour, Sina Khamaki, Rahem Rahmati, Andrei Surguchov   +10 more
wiley   +1 more source

Metabolic brain networks in dementia with Lewy bodies: from prodromal to manifest disease stages. [PDF]

J Neurol Neurosurg Psychiatry
Perovnik M, Simončič U, Jamšek J, Gregorič Kramberger M, Brumberg J, Meyer PT, Perani D, Caminiti SP, Brendel M, Stockbauer AC, Camacho V, Alcolea D, Vandenberghe R, Van Laere K, Ko JH, Lee CS, Pardini M, Lombardo L, Padovani A, Pilotto A, Ochoa-Figueroa MA, Davidsson A, Cháfer-Pericás C, Álvarez-Sánchez L, Garibotto V, Lemstra AW, Ferreira D, Morbelli SD, Tang CC, Eidelberg D, Trošt M, Alzheimer’s Disease Neuroimaging Initiative.   +31 more
europepmc   +1 more source