Results 181 to 190 of about 33,878 (250)

Higher-molecular-weight a-synuclein oligomers are increased in the brain cytosol of patients with dementia with Lewy bodies. [PDF]

NPJ Parkinsons Dis
Gregersen E, Antorini MR, Reimer L, Zaccagnini L, Selkoe D, Bartels T, Jensen PH.   +6 more
europepmc   +1 more source

Alzheimer's Biomarkers and Visuospatial Cognition in Parkinson's Disease: Modification by α‐Synuclein and Mediation of Age Effects

Movement Disorders Clinical Practice, Volume 13, Issue 8, Page 1861-1875, August 2026.
Abstract Background Visuospatial deficits in Parkinson's disease (PD) often precede dementia and complicate daily functioning. Alzheimer's disease (AD) pathology and α‐synuclein aggregation frequently co‐occur in PD, but their combined impact on cognition is unclear.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Meher Lad, Mark R. Baker, Nicola Pavese   +8 more
wiley   +1 more source

Inflammatory changes in early dementia with Lewy bodies. [PDF]

Front Neurol
Yacoubian TA, Qin H, Amara A, Stover N, Ruffrage L, Zhang Y, Kennedy R, Geldmacher D, Gerstenecker A, Standaert DG, Benveniste EN.   +10 more
europepmc   +1 more source

Biomarker‐Based Diagnosis and Care Pathways for Alzheimer's Disease in the Era of Disease‐Modifying Treatments: A Consensus Statement by Belgian Experts

European Journal of Neurology, Volume 33, Issue 8, August 2026.
ABSTRACT Background The recent approval of disease‐modifying therapies (DMTs) for early Alzheimer's disease (AD) marks a major shift in clinical practice. Biomarker confirmation of amyloid pathology is now required alongside clinical assessment, and blood‐based tests are improving accessibility.
Tim Van Langenhove, Sara Van Mossevelde, Marijke Miatton, Jan De Lepeleire, Rose Bruffaerts, Jean Christophe Bier, Kurt Segers, Jurn Verschraegen, Mirko Petrovic, Manfredi Ventura, Haroun Jedidi, Ingo Beyer, Eric Mormont, Rik Vandenberghe, Aline Delva, Christian Gilles, Donatienne Van Weehaeghe, Gaëtane Picard, Peter De Deyn, Mélanie Strauss, Evert Thiery, Eric Salmon, Gert Cypers, Joris Vlaemynck, Katrin Gillis, Jan Versijpt, Maria Bjerke, Anne Sieben, Bernard Hanseeuw, Sebastiaan Engelborghs, Olivier Deryck, on behalf of the BeDeCo members   +31 more
wiley   +1 more source

Delineation of the cognitive and neuropsychiatric features of Pisa syndrome in dementia with Lewy bodies. [PDF]

Front Aging Neurosci
Su Z, Kuai J, Yi T, Wu H, Gan J, Shi Z, Liu S, Ji Y.   +7 more
europepmc   +1 more source

Decoding Prodromal Lewy Body Disease: Clinical Differences Between Isolated REM Sleep Behavior Disorder and Hyposmia With Dopamine Transporter Deficit

European Journal of Neurology, Volume 33, Issue 8, August 2026.
Isolated REM sleep behavior disorder (iRBD) [n = 360] and hyposmia with dopamine transporter deficit [n = 1101] represent two enriched prodromal Lewy body disease cohorts. Using data from the Parkinson's Progression Markers Initiative, iRBD was associated with significantly greater autonomic symptom burden than hyposmia, driven by constipation and ...
Luke Vikram Banerjee, Jacopo Pasquini, Robin Henderson, Nicola Pavese, Kirstie N. Anderson   +4 more
wiley   +1 more source

Association between visual hallucinations and α-synuclein oligomers in patients with dementia with Lewy bodies. [PDF]

Alzheimers Dement
Sekiya H, Franke L, Ono D, DeTure M, Ross OA, Day GS, Lachner C, Graff-Radford NR, McLean PJ, Ferman TJ, Dickson DW.   +10 more
europepmc   +1 more source

Gait Impairment and Alzheimer's Disease Pathology: A Narrative Review on Mechanistic Links

Geriatrics &Gerontology International, Volume 26, Issue 8, August 2026.
Gait impairment and AD‐related pathology may be linked through shared risks, preclinical AD changes, feedback effects of persistent gait dysfunction, and life‐course susceptibility, underscoring the importance of maintaining brain–body health across the lifespan. ABSTRACT In older adults, gait has emerged as an important indicator of overall health and
Ryota Sakurai, Manuel Montero‐Odasso
wiley   +1 more source

Comorbid Pathologies and Their Impact on Dementia with Lewy Bodies-Current View. [PDF]

Int J Mol Sci
Jellinger KA.
europepmc   +1 more source