Results 31 to 40 of about 50,400 (305)

Characterization of dementia with Lewy bodies (DLB) and mild cognitive impairment using the Lewy body dementia module (LBD‐MOD)

Alzheimer's & Dementia, 2021
The National Institute on Aging Alzheimer's Disease Research Center program added the Lewy body dementia module (LBD‐MOD) to the Uniform Data Set to facilitate LBD characterization and distinguish dementia with Lewy bodies (DLB) from Alzheimer's disease (
J. Galvin, Stephanie Chrisphonte, I. Cohen, Keri K Greenfield, Michael J. Kleiman, Claudia Moore, M. L. Riccio, A. Rosenfeld, Niurka Shkolnik, Marcia I Walker, L. Chang, M. Tolea   +11 more
semanticscholar   +1 more source

Young-Onset Dementia with Lewy Bodies

Case Reports in Neurology, 2018
Young-onset (< 65 years) dementia is a challenging clinical problem. A 61-year-old man visited our clinic because of a 2-year history of mild cognitive impairment of the executive disorder type.
Yosuke Aiba, Ryuji Sakakibara, Tsuyoshi Ogata, Ayako Iimura, Keiichiro Terayama, Keiko Suzuki, Shuichi Katsuragawa, Yuuki Kato, Fuyuki Tateno, Hitoshi Terada, Tsutomu Inaoka, Tomoya Nakatsuka   +11 more
doaj   +1 more source

Prodromal dementia with Lewy bodies [PDF]

Psychological Medicine, 2014
BackgroundThe clinical condition of dementia is now recognized as a diagnosis that can only be applied too late in the disease process to be useful for therapeutic approaches centring on disease modification. As a result, in recent years increasing attention has been given to mild cognitive impairment (MCI) and the diagnosis of prodromal dementia. This
P C, Donaghy, J T, O'Brien, A J, Thomas
openaire   +2 more sources

Are dementia with Lewy bodies and Parkinson’s disease dementia the same disease?

BMC Medicine, 2018
BackgroundDementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD), which share many clinical, neurochemical, and morphological features, have been incorporated into DSM-5 as two separate entities of major neurocognitive disorders with Lewy
K. Jellinger, A. Korczyn
semanticscholar   +1 more source

Subtypes of dementia with Lewy bodies are associated with α-synuclein and tau distribution

Neurology, 2020
Objective To determine whether Lewy body disease subgroups have different clinical profiles. Methods Participants had dementia, autopsy-confirmed transitional or diffuse Lewy body disease (TLBD or DLBD) (n = 244), or Alzheimer disease (AD) (n = 210), and
T. Ferman, N. Aoki, B. Boeve, J. Aakre, K. Kantarci, J. Graff‐Radford, J. Parisi, J. V. van Gerpen, N. Graff-Radford, R. Uitti, Otto Pedraza, M. Murray, Z. Wszolek, R. R. Reichard, J. Fields, O. Ross, D. Knopman, R. C. Petersen, D. Dickson   +18 more
semanticscholar   +1 more source

Exploration Shared Pathological Mechanisms in Dementia with Lewy Bodies and Alzheimer's Disease Based on Serum microRNA Expression Profiling [PDF]

Alzheimers Dement
Ma X, Zhang W, Tang C, Wang H.
europepmc   +2 more sources

Dementia with Lewy bodies: an update and outlook

Molecular Neurodegeneration, 2019
Dementia with Lewy bodies (DLB) is an age-associated neurodegenerative disorder producing progressive cognitive decline that interferes with normal life and daily activities.
T. Outeiro, D. Koss, D. Erskine, Lauren Walker, M. Kurzawa-Akanbi, D. Burn, P. Donaghy, C. Morris, John-Paul Taylor, Alan J. Thomas, J. Attems, I. McKeith   +11 more
semanticscholar   +1 more source

Clinico‐pathological comparison of patients with autopsy‐confirmed Alzheimer's disease, dementia with Lewy bodies, and mixed pathology

Alzheimer's & Dementia, 2021
Patients with Alzheimer's disease (AD) and dementia with Lewy bodies (DLB) frequently demonstrate coexistent AD neuropathological change (ADNC) and Lewy body pathology (LBP) at autopsy.
Atri Chatterjee, Veronica Hirsch-Reinshagen, Syed Ali Moussavi, Blake Ducharme, I. Mackenzie, G. Hsiung   +5 more
semanticscholar   +1 more source

Introduction of an assessment toolkit associated with increased rate of DLB diagnosis

Alzheimer’s Research & Therapy, 2021
Background Dementia with Lewy bodies (DLB) and dementia in Parkinson’s disease (PDD) are recognised to be under-recognised in clinical practice in the UK, with only one third to a half of expected cases diagnosed.
A. Surendranathan, J. Kane, A. Bentley, S. Barker, R. McNally, C. Bamford, J.-P. Taylor, A. Thomas, I. McKeith, D. Burn, J. T. O’Brien   +10 more
doaj   +1 more source

Identification of the sites of tau hyperphosphorylation and activation of tau kinases in synucleinopathies and Alzheimer's diseases.

PLoS ONE, 2013
ObjectiveMost neurodegenerative diseases contain hyperphosphorylated Tau [p-Tau]. We examined for the first time epitopes at which Tau is hyperphosphorylated in Parkinson's disease, dementia with Lewy bodies and Alzheimer's disease, and also select Tau ...
Valeriy Duka, Jae-Hoon Lee, Joel Credle, Jonathan Wills, Adam Oaks, Ciaran Smolinsky, Ketul Shah, Deborah C Mash, Eliezer Masliah, Anita Sidhu   +9 more
doaj   +1 more source