Results 41 to 50 of about 50,400 (305)
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2021 Dementia with Lewy bodies (DLB) research has seen a significant growth in international collaboration over the last three decades. However, researchers face a challenge in identifying large and diverse samples capable of powering longitudinal studies and
Fabrizia D'Antonio +17 more
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Dementia with Lewy bodies [PDF]
Reviews in Clinical Gerontology, 1997 Dementia with Lewy bodies (DLB) is being increasingly recognized as a common cause of progressive cognitive decline in the elderly, with hospital-based autopsy series demonstrating rates of between 7% and 25% of all cases of dementia, second only in frequency to Alzheimer's disease (AD).
J Allardyce, IG McKeith
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Evolution of prodromal Parkinson's disease and dementia with Lewy bodies: a prospective study.
Brain : a journal of neurology, 2019 Parkinson's disease has a long prodromal stage with various subclinical motor and non-motor manifestations; however, their evolution in the years before Parkinson's disease is diagnosed is unclear.
S. Fereshtehnejad +5 more
semanticscholar +1 more source
Continuum, 2016 This article provides an overview of the clinical features, neuropathologic findings, diagnostic criteria, and management of dementia with Lewy bodies (DLB) and Parkinson disease dementia (PDD), together known as the Lewy body dementias.DLB and PDD are common, clinically similar syndromes that share characteristic neuropathologic changes, including ...
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Prodromal Dementia With Lewy Bodies: Clinical Characterization and Predictors of Progression
Movement Disorders, 2020 The objective of this study was to examine clinical characteristics, cognitive decline, and predictors for time to dementia in prodromal dementia with Lewy bodies with mild cognitive impairment (MCI‐LB) compared with prodromal Alzheimer's disease (MCI‐AD)
M. van de Beek +6 more
semanticscholar +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez +12 more
wiley +1 more source
Parkinson's Disease, 2012 Dementia is a common feature in Parkinson’s disease (PD) and is considered to be the result of limbic and cortical Lewy bodies and/or Alzheimer changes.
Simone A. van den Berge +3 more
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Renal Failure in Dementia with Lewy Bodies Presenting as Catatonia
Case Reports in Neurology, 2013 Catatonia, originally described by Karl Kahlbaum in 1874, may be regarded as a set of clinical features found in a subtype of schizophrenia, but the syndrome may also stem from organic causes including vascular parkinsonism, brain masses, globus pallidus
Robert Fekete
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Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2023 The regulatory path for drug approval is increasingly well defined. Drugs for the treatment of Alzheimer disease (AD) need to show statistically significant benefit over placebo with respect to cognitive and functional measures, with the Clinical ...
Marwan N. Sabbagh +9 more
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An Out‐of‐Place Etiology: Recognizing FMR1 Premutation in the Memory Clinic
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The FMR1 gene premutation (55–200 CGG repeats) is usually associated with a wide range of symptoms and phenotypes within the Fragile X‐tremor/ataxia syndrome (FXTAS), but may also manifest as predominant or isolated cognitive decline. We describe three male patients referred for progressive cognitive impairment and behavioral changes. Standard
Guido Greco +7 more
wiley +1 more source