Results 71 to 80 of about 50,400 (305)

Brainstem atrophy in dementia with Lewy bodies compared with progressive supranuclear palsy and Parkinson’s disease on MRI

BMC Neurology, 2023
Background Although Dementia with Lewy bodies (DLB) is the second most common form of dementia in elderly patients, it remains underdiagnosed compared with Alzheimer's (AD) and Parkinson's diseases (PD).
Sebastian Johannes Müller, Eya Khadhraoui, Niels Hansen, Ala Jamous, Philip Langer, Jens Wiltfang, Christian Heiner Riedel, Caroline Bouter, Christoph van Riesen, Fabian Maass, Michael Bartl, Claudia Lange, Marielle Ernst   +12 more
doaj   +1 more source

The Phenotypic Spectrum of Sporadic Creutzfeldt‐Jakob Disease Cortical Subtype

Annals of Neurology, EarlyView.
Objective The objective of this study was to characterize the phenotypic spectrum of the rare sporadic Creutzfeldt‐Jakob disease cortical subtype (sCJDMM/MV2C) in a large multicentric autopsy cohort. Methods We evaluated clinical histories, biofluid markers, brain diffusion‐weighted (DW)‐magnetic resonance imaging (MRI), and electroencephalogram (EEG ...
Simone Baiardi, Claudia Marina Vargiu, Brian S. Appleby, Marcelo Barria, Giuseppe Mario Bentivenga, Ignazio Calì, Benedetta Carlà, Mark Cohen, Armin Giese, Jochen Herms, Aino‐Minerva Kortelainen, Anna Ladogana, Angela Mammana, Diane Ritchie, Otto Windl, Sabina Capellari, Piero Parchi   +16 more
wiley   +1 more source

Investigation of the genetic aetiology of Lewy body diseases with and without dementia [PDF]

, 2023
Lesley Wu, Raquel Real, Alejandro Martínez-Carrasco, Ruth Chia, Michael Lawton, Maryam Shoai, Catherine Bresner, Leon Hubbard, Cornelis Blauwendraat, Andrew Singleton, Mina Ryten, Sonja W. Scholz, Bryan J. Traynor, Nigel Williams, Joshua Shulman, Yoav Ben‐Shlomo, Donald G. Grosset, John Hardy, Huw R. Morris   +18 more
openalex   +1 more source

Diagnostic Criteria for Dementia with Lewy Bodies: Updates and Future Directions

Journal of Movement Disorders, 2019
The aim of this article is to describe the 2017 revised consensus criteria for the clinical diagnosis of dementia with Lewy bodies (DLB) with future directions for the diagnostic criteria.
M. Yamada, J. Komatsu, Keiko Nakamura, K. Sakai, Miharu Samuraki-Yokohama, K. Nakajima, M. Yoshita   +6 more
semanticscholar   +1 more source

Speech Biomarkers From Smartphone Calls Track Progression in REM Sleep Behavior Disorder and Parkinson's Disease

Annals of Neurology, EarlyView.
Objective This 24‐month longitudinal study involving isolated rapid eye movement sleep behavior disorder (iRBD), early‐stage Parkinson's disease (PD), and matched healthy control subjects aimed to assess whether acoustic speech features from real‐world smartphone calls provide passive progressive biomarkers in synucleinopathies.
Michal Šimek, Tereza Tykalová, Michal Novotný, Vojtěch Illner, Tomáš Kouba, Martin Šubert, Pavel Sovka, Jan Švihlík, Evžen Růžička, Karel Šonka, Petr Dušek, Jan Rusz   +11 more
wiley   +1 more source

Frailty in Older Adults with Mild Dementia: Dementia with Lewy Bodies and Alzheimer’s Disease

Dementia and Geriatric Cognitive Disorders Extra, 2019
Introduction: The aim of the study is to describe the frequency of frailty in people with a new diagnosis of mild dementia due to Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB). Methods: This is a secondary analysis of the Dementia Study of
Miguel Germán Borda, Hogne Soennesyn, Claire J. Steves, Audun Osland Vik-Mo, Mario Ulises Pérez-Zepeda, Dag Aarsland   +5 more
doaj   +1 more source

Dementia with Lewy bodies – a clinicopathological update

Free Neuropathology, 2020
Dementia is one of the major burdens of our aging society. According to certain predictions, the number of patients will double every 20 years. Although Alzheimer’s disease (AD), as the most frequent neurodegenerative dementia, has been extensively ...
János Bencze, Woosung Seo, Abdul Hye, Dag Aarsland, Tibor Hortobágyi   +4 more
doaj   +1 more source

Pharmacological Management of Dementia with Lewy Bodies

Drugs & Aging, 2019
Dementia with Lewy bodies (DLB) is a complex disease that involves a variety of cognitive, behavioral and neurological symptoms, including progressive memory loss, visual hallucinations, parkinsonism, cognitive fluctuations and rapid eye movement sleep ...
L. Hershey, R. Coleman-Jackson
semanticscholar   +1 more source

Understanding Neurodegenerative Diseases From the −Omics Perspective: Lessons Learnt

Annals of Neurology, EarlyView.
As the population ages, certain neurodegenerative diseases (NDs) are becoming a major health issue. For this reason, this review will focus on the most common ND with onset after 65 years old; Alzheimer's disease, Parkinson's disease, Lewy body dementia, and frontotemporal dementia.
Laura Ibanez, Cyril Pottier, Aleksandra Beric, Daniel Western, Muhammad Ali, Carlos Cruchaga   +5 more
wiley   +1 more source

An Investigation of Hyperostosis Frontalis Interna in a Modern Anatomical Body Donor Population

Clinical Anatomy, EarlyView.
ABSTRACT This research sought to examine the prevalence and severity of hyperostosis frontalis interna (HFI) in the Chicagoland anatomical body donor population. The study further aimed to elucidate potential demographic risk factors for HFI, including sex, age at death, and structural vulnerability index (SVI), as well as any common comorbidities, as ...
Amy C. Beresheim, Amanda Hall
wiley   +1 more source