Results 31 to 40 of about 2,546 (159)

Influence of different drying techniques on the quality and physicochemical properties of Ghana‐sourced turmeric (Curcuma longa L.) samples

JSFA reports, EarlyView.
Abstract Background This study evaluated the influence of four drying techniques—freeze drying (FZD), microwave drying (MCD), oven drying (OVD), and sun drying (SUD)—on the bioactive, nutritional, and physical properties of turmeric. Using standard analytical procedures, the samples were examined for antioxidant activity (DPPH and ABTS assays), total ...
Eric Antiri Aforo, Richard Osae, Maurice Tibiru Apaliya, Irene Akua Idun, Emmanuel Kwaw, Raphael N. Alolga, Francis Appiah   +6 more
wiley   +1 more source

Quantitative analysis of curcumin compounds in ginger by ultra-high-performance liquid chromatography coupled with tandem mass spectrometry

Food Innovation and Advances
Curcumin compounds are important bioactive compounds in ginger, yet their analysis is limited by their low concentrations. In the current research, a highly sensitive and reliable approach for simultaneous quantitative detection of three curcumin ...
Yixuan Jiang, Xiuhua Liu, Yinfeng Zhao, Jiguang Zhang, Jing Qiu, Yongzhong Qian, Rui Weng   +6 more
doaj   +1 more source

Demethoxycurcumin-Loaded Chitosan Nanoparticle Downregulates DNA Repair Pathway to Improve Cisplatin-Induced Apoptosis in Non-Small Cell Lung Cancer

Molecules, 2018
Demethoxycurcumin (DMC), through a self-assembled amphiphilic carbomethyl-hexanoyl chitosan (CHC) nanomatrix has been successfully developed and used as a therapeutic approach to inhibit cisplatin-induced drug resistance by suppressing excision repair ...
Ying-Yi Chen, Yu-Jung Lin, Wei-Ting Huang, Chin-Chuan Hung, Hui-Yi Lin, Yu-Chen Tu, Dean-Mo Liu, Shou-Jen Lan, Ming-Jyh Sheu   +8 more
doaj   +1 more source

Antimicrobial photodynamic therapy in Candida spp. biofilms: In vitro and in vivo protocols

Photochemistry and Photobiology, EarlyView.
This review addresses the critical challenges in translating in vitro antimicrobial photodynamic therapy protocols to in vivo models, with a particular focus on the hurdles of standardization. The vast diversity in photosensitizers and light parameters across different target cells and models requires a rigorous optimization process.
Lívia Mara Alves Figueiredo‐Godoi, Ana Júlia Barbosa Tomé, Cristina Kurachi   +2 more
wiley   +1 more source

An isoxazole strategy for the synthesis of curcumin and demethoxycurcumin

Synthetic Communications
Curcumin and demethoxycurcumin were synthesized via an isoxazole-masking strategy. A 3,5-disubstituted isoxazole, obtained by [3 + 2] cycloaddition of a nitrile oxide and an alkyne, underwent mild reductive N-O cleavage to reveal the β-diketone core in good yield.
Kato, Mirai, Sugihara, Kyosuke, Tanaka, Aki, Tanaka, Rina, Abe, Hitoshi   +4 more
openaire   +1 more source

Photodynamic Action of Synthetic Curcuminoids against Staphylococcus aureus: Experimental and Computational Evaluation

Chemistry
Natural curcumin is composed of three curcuminoids, namely curcumin (CUR), deme-thoxycurcumin (DMC) and bis-demethoxycurcumin (BDMC). These compounds are utilized in various biophotonics applications, including photodynamic therapy (PDT). This work aimed
Nícolas J. Melo, Jennifer M. Soares, Lívia N. Dovigo, Christian Carmona-Vargas, Antônio S. N. Aguiar, Adriana C. dos Passos, Kleber T. de Oliveira, Vanderlei S. Bagnato, Lucas D. Dias, Natalia Inada   +9 more
doaj   +1 more source

Antioxidant, Antidiabetic and Cytoprotective Activities of Synthetic Chloro‐Curcumin Derivatives in C2C12 Myotubes

Applied Research, Volume 5, Issue 4, August 2026.
Structural reengineering of curcumin generated derivatives with antioxidant, cytoprotective and glucose‐modulating activities. These compounds improved cellular responses to hyperglycaemic stress in C2C12 myotubes, highlighting their potential as candidates for managing oxidative stress–related metabolic disorders, particularly type 2 diabetes mellitus.
Adesola Oluwaseun Adeleye, Oluwafemi Omoniyi Oguntibeju, Salam Titinchi, Chinyerum Sylvia Opuwari   +3 more
wiley   +1 more source

Associating gene expressions with curcuminoid biosynthesis in turmeric

Journal of Genetic Engineering and Biotechnology, 2020
Background Biologically important curcuminoids viz curcumin, demethoxycurcumin, and bisdemethoxycurcumin in turmeric rhizome have several health benefits. Pharmaceutical industries synthesize curcuminoids manipulating gene expressions in vitro or in vivo
Dipendra Kumar Ayer, Kaushal Modha, Vipulkumar Parekh, Ritesh Patel, Gopal Vadodariya, Vinita Ramtekey, Arpit Bhuriya   +6 more
doaj   +1 more source

Selective Anti‐Inflammatory Actions of Curcumin on Cytokine Pathways in Major Depressive Disorder

Brain and Behavior, Volume 16, Issue 8, August 2026.
Curcumin partially attenuates IRS/M1/Th1 immune activation in MDD patients ex vivo, but fails to normalize it. Paradoxically, it upregulates immune profiles in healthy controls. Its immunomodulatory effects are state‐dependent, suggesting cautious use in non‐depressed individuals.
Tangcong Chen, Yueyang Luo, Mengqi Niu, Jing Li, Mengdie Li, Yingqian Zhang, Michael Maes   +6 more
wiley   +1 more source

Demethoxycurcumin inhibits cell proliferation, migration and invasion in prostate cancer cells

Oncology Reports, 2012
Curcumin (CUR) is a natural agent that has been demonstrated to effectively inhibit prostate cancer growth. However, natural CUR is relatively unstable and can be easily degraded in vivo. Therefore, it is essential to develop other stable curcuminoids. Demethoxycurcumin (DMC) is a candidate that has been verified in
Xiaochen, Ni, Aili, Zhang, Zhihong, Zhao, Yongqing, Shen, Shijie, Wang   +4 more
openaire   +3 more sources