Results 11 to 20 of about 2,546 (159)

Disruptive Effects of Two Curcuminoids (Demethoxycurcumin and Bisdemethoxycurcumin) on the Larval Development of Drosophila melanogaster

Insects, 2023
Juvenile hormones (JHs) play a central role in insect development, reproduction, and various physiological functions. Curcuminoids generally exhibit a wide range of biological activities, such as antioxidant, anti-inflammatory, antibacterial, and ...
Jun-Hyoung Jeon, Seon-Ah Jeong, Doo-Sang Park, Hong-Hyun Park, Sang-Woon Shin, Hyun-Woo Oh   +5 more
doaj   +3 more sources

Protective effects of turmeric extract, curcumin, demethoxycurcumin, bis-demethoxycurcumin, and ar-turmerone from Curcuma longa L. rhizomes on acetaminophen-induced hepatotoxicity in HepG2 cells

Asian Pacific Journal of Tropical Biomedicine
Objective: To assess the effects of turmeric extract and its compounds on oxidative stress, inflammation, and apoptosis in acetaminophen-induced liver injury.
Wahyu Widowati, Dian Ratih Laksmitawati, Diah Kartika Pratami, Deni Rahmat, S. Ravi Kiran, J. Achyutha Devi, Didik Priyandoko, Nindia Salsabila Mia Dewi, Annisa Firdaus Sutendi, Rizal Azis, Dhanar Septyawan Hadiprasetyo, Mariska Elizabeth   +11 more
doaj   +2 more sources

MicroRNA 145 enhances chemosensitivity of glioblastoma stem cells to demethoxycurcumin

Cancer Management and Research, 2019
Chunfa Qian,*,1 Bin Wang,*,2 Yuanjie Zou,*,1 Yansong Zhang,*,1 Xinhua Hu,*,1 Wenbo Sun,*,1 Hong Xiao,*,3 Hongyi Liu,1 Lei Shi21Department of Neurosurgery, Nanjing Brain Hospital Affiliated to Nanjing Medical University,
Qian C, Wang B, Zou Y, Zhang Y, Hu X, Sun W, Xiao H, Liu H, Shi L   +8 more
doaj   +4 more sources

Structure and Dynamics of the Deprotonated Demethoxycurcumin and Bisdemethoxycurcumin Anions. [PDF]

J Phys Chem A
The curcuminoids are polyphenols found in the spice turmeric, where its principal polyphenol, curcumin, has been attributed with many of turmeric's beneficial therapeutic properties. However, as curcumin has a low bioavailability, other curcuminoids, which have fewer terminal methoxy substituents and have been reported to have a higher bioavailability,
Gibbard JA.
europepmc   +4 more sources

One Pot Synthesis of the C-3 Complex (Curcumin, Demethoxycurcumin, and Bis-Demethoxycurcumin): Their Joint and Independent Biological Actions. [PDF]

Int J Mol Sci
Curcumin (CUR) is the primary metabolite isolated from the Curcuma longa L. rhizome. Most synthetic and biological studies have focused mainly on the curcumin molecule due to its essential biological activity as an antioxidant, anti-cancer, and anti-Alzheimer’s disease agent.
Obregón-Mendoza MA, Sánchez-Obregón R, Tavera-Hernández R, Pérez-González LL, Nieto-Camacho A, Rodríguez-Sotres R, Escobedo-Martínez C, Romero I, Enríquez RG.   +8 more
europepmc   +3 more sources

Study on Demethoxycurcumin as a Promising Approach to Reverse Methicillin-Resistance of Staphylococcus aureus [PDF]

International Journal of Molecular Sciences, 2021
Methicillin-resistant Staphylococcus aureus (MRSA) has always been a threatening pathogen. Research on phytochemical components that can replace antibiotics with limited efficacy may be an innovative method to solve intractable MRSA infections.
Qian-Qian Li, Ok-Hwa Kang, Dong-Yeul Kwon   +2 more
openaire   +3 more sources

Polyphenolic HRMS Characterization, Contents and Antioxidant Activity of Curcuma longa Rhizomes from Costa Rica

Antioxidants, 2022
Curcuma longa constitutes an important source of secondary metabolites that have been associated with multiple health benefits. For instance, curcumin, demethoxycurcumin and bisdemethoxycurcumin, have been found to perform important biological activities,
María Isabel Quirós-Fallas, Felipe Vargas-Huertas, Silvia Quesada-Mora, Gabriela Azofeifa-Cordero, Krissia Wilhelm-Romero, Felipe Vásquez-Castro, Diego Alvarado-Corella, Andrés Sánchez-Kopper, Mirtha Navarro-Hoyos   +8 more
doaj   +1 more source

Demethoxycurcumin ameliorates rotenone-induced toxicity in rats

Frontiers in Bioscience, 2019
Rotenone, an environmental toxin, is used to induce neurodegeneration in both the cellular and animal model of Parkinson's disease. Demethoxycurcumin (DMC), derivative of curcumin has been reported to have antioxidant and anti-inflammatory characteristics in in vitro and in vivo PD conditions. The present study was aimed to evaluate the efficacy of DMC
Muthu, Ramkumar, Srinivasagam, Rajasankar, William Moses, Swaminathan Johnson, Kaliyaperumal, Prabu, Veerappan, Venkatesh Gobi   +4 more
openaire   +2 more sources

Demethoxycurcumin inhibited human epithelia ovarian cancer cells’ growth via up-regulating miR-551a

Tumor Biology, 2017
Curcumin is a natural agent that has ability to dampen tumor cells’ growth. However, the natural form of curcumin is prone to degrade and unstable in vitro.
Zhenhua Du, Xianqun Sha
doaj   +1 more source

Demethoxycurcumin in combination with ultraviolet radiation B induces apoptosis through the mitochondrial pathway and caspase activation in A431 and HaCaT cells

Tumor Biology, 2017
Photodynamic therapy is widely used in the clinical treatment of tumors, especially skin cancers. It has been reported that the photosensitizer curcumin, in combination with ultraviolet radiation B, induces HaCaT cell apoptosis, and this effect may be ...
Yong Xin, Qian Huang, Pei Zhang, Wen Wen Guo, Long Zhen Zhang, Guan Jiang   +5 more
doaj   +1 more source