Results 21 to 30 of about 2,546 (159)
Taiwanese Journal of Obstetrics & Gynecology, 2012 Objective: This study aims to determine the effects of curcumin and demethoxycurcumin on the internal ribosome entry site of the amyloid-β precursor protein (APP) and tau protein through a bi-cistronic reporter assay for screening of anti-Alzheimer's ...
Oliver B. Villaflores +4 more
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Journal of Spectroscopy, 2013 Two questions are asked: the first is if the lack/presence of methoxyl moiety at aromatic ring essentially affects the stability of curcuminoid-metal complexes, and the second is if it is possible that in the metal complexes one of the possible ...
Wojciech Ostrowski +3 more
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Applied Biological Chemistry, 2023 Studies on the use of natural products to treat cancer are ongoing, and turmeric (Curcuma longa L.), a medicinal crop, is known for various effects including anticancer activity. In this study, the inhibitory effect of C.
Dahye Yoon +5 more
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Journal of Enzyme Inhibition and Medicinal Chemistry, 2023 Curcuminoids are functional food additives, and the effect on gonadal hormone biosynthesis remains unclear. Gonads contain 3β-hydroxysteroid dehydrogenase isoforms, h3β-HSD2 (humans) and r3β-HSD1 (rats), which catalyse pregnenolone into progesterone. The
Xinyi Qiao +9 more
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Apoptotic activity of demethoxycurcumin in MG-63 human osteosarcoma cells
International Journal of Oral Biology, 2021 Demethoxycurcumin (DMC), which is a curcuminoid found in turmeric, has anti-proliferative effects on cancer cells. However, the effect of DMC on osteosarcoma has not been established. The aim of this study was to examine the effects of DMC on cell growth and apoptosis induction in MG-63 human osteosarcoma cells.
Kyeong-Rok Kang +9 more
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Translational OncologyIn the occurrence and progression of breast cancer, tumor angiogenesis and metastasis play a central role. This indicates that anti-angiogenesis holds a significant position in anti-tumor therapy. Demethoxycurcumin is a bioactive diarylheptanoid compound
Jie Chen +6 more
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Heliyon, 2023 Background: The spice curcumin is supposed to have many different beneficial health effects. To understand the complete pharmacokinetics of curcumin we need an analytical method to determine curcumin and its metabolites in human plasma, urine or feces ...
M.A.G.M. Kroon +4 more
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Molecules, 2016 In the present study, we examined the ameliorating effects of demethoxycurcumin (DMC) on memory impairment induced by scopolamine using passive avoidance and Morris water maze tests in mice.
Dong Wook Lim +6 more
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Applied Sciences, 2021 Curcuminoids, the bioactive compounds with many beneficial effects on human health, exist in Curcuma longa (turmeric). In the present study, the impact of different cell disintegration techniques to enhance total curcuminoid recovery (TC) from fresh and ...
Hoang Le-Tan +5 more
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Effects of demethoxycurcumin on the viability and apoptosis of skin cancer cells
Molecular Medicine Reports, 2017 The present study investigated the effects and mechanisms of demethoxycurcumin (DMC) on a human skin squamous cell carcinoma cell line, A431, and a human keratinocyte cell line, HaCaT. A431 and HaCaT cells were cultured in vitro. The effects of DMC treatment on cell viability were analyzed using the Cell Counting kit‑8 (CCK‑8) assay; cell cycle ...
Wu, Yaoqun +4 more
openaire +3 more sources