Results 171 to 180 of about 98,772 (389)

Histone H3K27 demethylase UTX compromises articular chondrocyte anabolism and aggravates osteoarthritic degeneration [PDF]

open access: gold, 2022
Wei‐Shiung Lian   +7 more
openalex   +1 more source

Establishment of a mouse model of TMAO‐induced cardiac injury and application of MICT intervention

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study aims to explore the establishment of an animal model of cardiac injury induced by trimethylamine‐N‐oxide (TMAO), a metabolite secreted by gut microorganisms, and to investigate its application in moderate‐intensity continuous training (MICT) intervention.
Zhongping Xie   +4 more
wiley   +1 more source

Small molecule inhibitors targeting sterol 14α-demethylase (CYP51): synthesis, molecular modeling and evaluation against Candida albicans

open access: gold, 2020
Faizah A. Binjubair   +5 more
openalex   +1 more source

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

open access: yesBMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang   +6 more
wiley   +1 more source

The lysine demethylase, KDM4B, is a key molecule in androgen receptor signalling and turnover [PDF]

open access: gold, 2013
Kelly Coffey   +13 more
openalex   +1 more source

Mapping molluscan endocrinology: a systematic and critical appraisal

open access: yesBiological Reviews, EarlyView.
ABSTRACT Historically, a vertebrate‐centric paradigm has framed our interpretation of molluscan endocrinology, with considerable research focusing on vertebrate‐type steroid hormones (e.g. oestrogens, testosterone). However, contradictory evidence on the occurrence of vertebrate‐type steroid hormones in molluscan tissues, and a lack of the specific ...
Konstantinos Panagiotidis   +3 more
wiley   +1 more source

ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility.

open access: yesMolecules and Cells, 2013
G. Zheng   +27 more
semanticscholar   +1 more source

Differences in the expression of DNA methyltransferases and demethylases in leukocytes and the severity of pulmonary arterial hypertension between ethnic groups

open access: gold, 2022
Catherine D’Addario   +6 more
openalex   +1 more source

Recent Advances in Chemical Probing Strategies for RNA Structure Determination in Vivo

open access: yesChemistry – A European Journal, EarlyView.
This Review illustrates how structural probes combined with advanced sequencing technologies are revolutionizing our ability to map RNA structures and interactions within living cells. It highlights the development of innovative strategies tailored to probe RNA structures in particular biological contexts.
Maryana Yarshova   +2 more
wiley   +1 more source

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