Results 171 to 180 of about 7,855 (246)
The FEBS Journal, EarlyView.N6‐methyladenosine is a key mRNA modification that regulates transcript turnover, translation, and other aspects of RNA fate. The m6A‐demethylase ‘eraser’ enzyme FTO reverses this modification. While FTO is known to promote oncogenic signaling in triple‐negative breast cancer, its wider role across the genome and specific downstream signaling has yet ...
Hidde R. Zuidhof +6 more
wiley +1 more source
The FEBS Journal, EarlyView.N6‐methyladenosine (m6A) is a frequently occurring RNA modification that has emerged as an important player in tumour development through post‐transcriptional gene regulation. In this study, we found that IGF2BP3 modulates HSP90AB1 expression in an m6A modification‐dependent manner, activating the PI3K/AKT‐signaling pathway, and thereby promoting the ...
Xiaoqing Chen +10 more
wiley +1 more source
The Histone H3 Lysine-27 Demethylase Jmjd3 Links Inflammation to Inhibition of Polycomb-Mediated Gene Silencing [PDF]
, 2007 Francesca De Santa +5 more
openalex +1 more source
DmdA‐independent lag phase shortening in Phaeobacter inhibens bacteria under stress conditions
The FEBS Journal, EarlyView.The lag phase is crucial for resuming bacterial growth and can be shortened by fueling the methionine cycle with methyl groups from DMSP or other methylated compounds. While DmdA is the primary DMSP demethylase in Phaeobacter inhibens, stress activates additional enzymes like Bmt. This enzymatic flexibility allows bacteria to exit the lag phase rapidly,
Delia A. Narváez‐Barragán +2 more
wiley +1 more source
Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases [PDF]
, 2007 Sunhwa Hong +5 more
openalex +1 more source
Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells [PDF]
, 2007 Yuin‐Han Loh +4 more
openalex +1 more source
Structure and Mechanism of Lysine-specific Demethylase Enzymes [PDF]
, 2007 Ruchi Anand, Ronen Marmorstein
openalex +1 more source