Results 231 to 240 of about 9,225,670 (325)

Silencing Nogo‐A promotes functional recovery in demyelinating disease [PDF]

open access: bronze, 2009
Yuhong Yang   +12 more
openalex   +1 more source

Apolipoprotein ε4 exacerbates white matter impairment in a mouse model of Aβ amyloidosis by decreasing actively myelinating oligodendrocytes

open access: yesAlzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract INTRODUCTION The ε4 allele of the apolipoprotein E (APOE) gene is a risk factor for the development of Alzheimer's disease (AD). APOE4 isoform is associated with increased white matter lesions in humans. To identify the underlying mechanisms of white matter impairment associated with APOE4, we investigated the effects of APOE4 and APOE3 on ...
Md Mamun Al‐Amin   +9 more
wiley   +1 more source

Nalfurafine reduces neuroinflammation and drives remyelination in models of CNS demyelinating disease. [PDF]

open access: yesClin Transl Immunology, 2021
Denny L   +6 more
europepmc   +1 more source

Molecular Biology, Epidemiology, and Pathogenesis of Progressive Multifocal Leukoencephalopathy, the JC Virus-Induced Demyelinating Disease of the Human Brain

open access: yesClinical Microbiology Reviews, 2012
Michael W. Ferenczy   +6 more
semanticscholar   +1 more source

Evaluation of CD3+CD56+ NKT and CD19+ B Cells in Assessing the Relapse of Neuromyelitis Optica Spectrum Disorder Patients Treated With Rituximab

open access: yesBrain and Behavior, Volume 15, Issue 10, October 2025.
This graphical abstract summarizes a study on 166 NMOSD patients treated with rituximab. Pre‐treatment assessment of peripheral CD3+CD56+ NKT cells and CD19+ B cells revealed that low NKT (≤9.85%) and high B cell (≥5.12%) levels are associated with increased relapse risk.
Jing Zeng   +3 more
wiley   +1 more source

Central Nervous System Tuberculosis: A Case of Tuberculous Myelitis

open access: yesClinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Tuberculous myelitis is rare in central nervous system (CNS) tuberculosis. Misdiagnosis initially may lead to poor outcomes; empirical antituberculosis treatment can improve symptoms. Early diagnosis via cerebrospinal fluid (CSF) and spinal MRI, plus timely treatment, is vital—clinical awareness needs enhancement.
Huan Nie   +4 more
wiley   +1 more source

Case of Severe Hiccups Causing SIADH, Treated With Lorazepam

open access: yesClinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT This is a presentation of severe hiccups which led to the syndrome of inappropriate antidiuretic hormone (SIADH). The patient presented after 3 days of severe hiccups associated with vomiting and oral intake intolerance. SIADH was diagnosed by hyponatremia (initial 128 millimoles/liter (mmol/L), nadir 119 mmol/L; normal range 136–146 mmol/L ...
Lisa Matlen
wiley   +1 more source

A Pathogenic Role for CD8+ T Cells in a Spontaneous Model of Demyelinating Disease

open access: bronze, 2006
Marcel Brisebois   +4 more
openalex   +1 more source

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