Results 51 to 60 of about 9,029,710 (297)
Frontiers in Genetics, 2019 Exosomes can pass through the blood-brain barrier and are present in the cerebrospinal fluid (CSF). The components in exosomes, such as DNA, RNA, protein, and lipids, change greatly and are closely related to disease progression.
Jinting He +6 more
doaj +1 more source
Learning Myelin Content in Multiple Sclerosis from Multimodal MRI through Adversarial Training [PDF]
, 2018 Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS). A reliable measure of the tissue myelin content is therefore essential for the understanding of the physiopathology of MS, tracking progression and assessing treatment efficacy.
arxiv +1 more source
Disrupted CXCR2 Signaling in Oligodendroglia Lineage Cells Enhances Myelin Repair in a Viral Model of Multiple Sclerosis. [PDF]
, 2019 CXCR2 is a chemokine receptor expressed on oligodendroglia that has been implicated in the pathogenesis of neuroinflammatory demyelinating diseases as well as enhancement of the migration, proliferation, and myelin production by oligodendroglia. Using an
Cheng, Yuting +9 more
core +1 more source
Differential diagnosis of demyelinating diseases: what's new?
Arquivos de Neuro-Psiquiatria, 2022 Background: Acquired demyelinating disorders lead to overlapping visual, pyramidal, sensory, autonomic, and cerebellar deficits and may lead to severe disability.
Ana Beatriz Ayroza Galvão Ribeiro Gomes +1 more
doaj +1 more source
Myelin Oligodendrocyte Glycoprotein: Deciphering a Target in Inflammatory Demyelinating Diseases
Frontiers in Immunology, 2017 Myelin oligodendrocyte glycoprotein (MOG), a member of the immunoglobulin (Ig) superfamily, is a myelin protein solely expressed at the outermost surface of myelin sheaths and oligodendrocyte membranes.
Patrick Peschl +4 more
semanticscholar +1 more source
Differential binding patterns of anti-sulfatide antibodies to glial membranes [PDF]
, 2018 Sulfatide is a major glycosphingolipid in myelin and a target for autoantibodies in autoimmune neuropathies. However neuropathy disease models have not been widely established, in part because currently available monoclonal antibodies to sulfatide may ...
Barrie, Jennifer A. +8 more
core +1 more source
Therapeutic potential of neuromodulation for demyelinating diseases
Neural Regeneration Research, 2021 Neuromodulation represents a cutting edge class of both invasive and non-invasive therapeutic methods which alter the activity of neurons. Currently, several different techniques have been developed - or are currently being investigated – to treat a wide
Elliot H Choi +5 more
doaj +1 more source
Magnetic resonance imaging diagnosis of demyelinating diseases: An update
Clinical and Experimental Neuroimmunology, 2019 Major demyelinating diseases include multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), acute disseminated encephalomyelitis (ADEM) and myelin oligodendrocyte glycoprotein (MOG) encephalomyelitis.
Y. Miki
semanticscholar +1 more source
Do we need broad immunological work-up in all patients with CIS? [PDF]
, 2012 BACKGROUND: The aim of this study was to determine the prevalence of altered immunological tests and their clinical significance in patients with clinically isolated syndrome (CIS) suggestive of multiple sclerosis (MS). ----- PATIENTS AND METHODS:
Adamec, Ivan +6 more
core +1 more source
Frontiers in Molecular Neuroscience, 2018 Multiple Sclerosis is a demyelinating disease of the central nervous system for which no remyelination therapy is available and alternative strategies are being tested.
I. Osorio-Querejeta +4 more
semanticscholar +1 more source