Results 221 to 230 of about 104,217 (332)

An Unusual Case of Extrapontine Myelinolysis in a Post-partum Woman with Hypernatremia. [PDF]

Ann Indian Acad Neurol
Rathore A, Nalini A, Netravathi M, Yadav R, Mundlamuri RC, Vengalil S, Raja P.   +6 more
europepmc   +1 more source

Remyelination as a therapeutic target in the treatment of multiple sclerosis. [PDF]

AIMS Neurosci
Garcha GK, Ahmed M.
europepmc   +1 more source

The potent and selective adenosine A2AR antagonists P400 and P625 protect against symptoms in autoimmune experimental encephalomyelitis by attenuating neuroinflammation and demyelination

Martina Morozzi, Vittoria Borgonetti, Chiara Sasia, Giacomina Videtta, Sara Calenda, Daniela Catarzi, Flavia Varano, Vittoria Colotta, Nicoletta Galeotti   +8 more
openalex   +1 more source

Induction of Heat Shock Protein 70 (Hsp70) prevents neuregulin-induced demyelination by enhancing the proteasomal clearance of c-Jun

, 2012
Chengyuan Li, Jiacheng Ma, Huiping Zhao, Brian S. J. Blagg, Rick T. Dobrowsky   +4 more
openalex   +1 more source

Conditional deletion of the multiple sclerosis susceptibility gene ATXN1 identifies cell‐autonomous effects in the B‐cell compartment

The FEBS Journal, EarlyView.
Ataxin‐1 is a polyglutamine protein associated with the etiology of spinocerebellar ataxia type 1 (SCA1) that has been recently found implicated in the risk of developing the autoimmune disorder multiple sclerosis (MS). Here, we took a conditional knockout approach to ablate ataxin‐1 exclusively in the B‐cell compartment and we found that this protein ...
Jonathan Jacob Carver, Rachael Riley Denbrock, Cindy Carolina Martines, Alessandro Didonna   +3 more
wiley   +1 more source

The Role of Lipid Alteration in Multiple Sclerosis. [PDF]

Int J Mol Sci
Damiza-Detmer A, Pawełczyk M, Głąbiński A.   +2 more
europepmc   +1 more source

MyD88 Deficiency Protects Mice From Experimental Autoimmune Encephalomyelitis by Influencing Both Dendritic Cells and T Cells

Immunology, EarlyView.
This study investigates the role of MyD88 in dendritic cells (DCs) and T cells during experimental autoimmune encephalomyelitis (EAE). We found that MyD88 is highly expressed in DCs and CD4+ T cells in people with multiple sclerosis, and its deficiency impairs DC maturation, reduces pro‐inflammatory cytokine production, weakens DC–T cell interactions ...
Wen Si, Gaochen Zhu, Qianling Jiang, Xin Ma, Guan Yang   +4 more
wiley   +1 more source

Sevoflurane Post-Conditioning Ameliorates Neuronal Deficits and Axon Demyelination After Neonatal Hypoxic Ischemic Brain Injury: Role of Microglia/Macrophage

, 2020
Hang Xue, Yahan Zhang, Qiushi Gao, Ziyi Wu, Jiayuan Niu, Chang Li, Ping Zhao   +6 more
openalex   +2 more sources

Sympathetic innervation of human cervical lymph nodes: A potential neuroimmunomodulatory target for the treatment of T‐cell‐driven autoimmune diseases like MS?

Journal of Anatomy, EarlyView.
Recent animal studies have shown that the sympathetic nervous system (SNS) prevents disease activity of EAE (Experimental autoimmune encephalomyelitis, animal model of Multiple Sclerosis [MS]), presumably through adrenergic activity in the deep cervical lymph nodes (DCLNs).
Christopher Kremer, Claire Mackaaij, Suzanne A. M. W. Verlinde‐Schellekens, Ronald L. A. W. Bleys, Cindy G. J. Cleypool   +4 more
wiley   +1 more source

Tumefactive Demyelinating Lesion Mimicking Low-Grade Astrocytoma with a T2/FLAIR Mismatch Sign: A Case Report and Review of the Literature. [PDF]

Diagnostics (Basel)
Karhu M, Tumeļkāns R, Dzirkale D, Auslands K, Özütemiz C, Flintere Flinte A, Balodis A.   +6 more
europepmc   +1 more source