Results 201 to 210 of about 106,551 (295)

Automated Surface‐Based Segmentation of Deep Gray Matter Regions Based on Diffusion Tensor Images Reveals Unique Age Trajectories Over the Healthy Lifespan

open access: yesNMR in Biomedicine, Volume 39, Issue 8, August 2026.
This paper introduces a novel, automated deep gray matter segmentation method that relies exclusively on diffusion‐weighted imaging, eliminating the need for T1‐weighted images. When applied to a lifespan cohort from ages 5 to 90, the technique successfully mapped distinct, nonlinear developmental and aging trajectories for microstructural diffusion ...
Graham Little   +2 more
wiley   +1 more source

Opioid Signaling in Multiple Sclerosis: Emerging Targets for Repair. [PDF]

open access: yesInt J Mol Sci
Perlikowska R   +3 more
europepmc   +1 more source

Standard Model Imaging in the Brain and Spinal Cord of MS Patients: Initial Assessment and Comparison to Diffusion Tensor Imaging

open access: yesNMR in Biomedicine, Volume 39, Issue 8, August 2026.
DTI and SMIfw diffusion models applied in persons with multiple sclerosis revealed region‐specific sensitivity to microstructural injury, but performance differed by anatomical region. SMIfw neurite density fraction demonstrated high sensitivity and reliability in both the brain and spinal cord, whereas DTI measures such as fractional anisotropy and ...
Atlee Witt   +8 more
wiley   +1 more source

High‐Resolution Diffusion Kurtosis Imaging of Hippocampus Subfields Across the Healthy Lifespan

open access: yesNMR in Biomedicine, Volume 39, Issue 8, August 2026.
Developmental and aging changes were examined in the hippocampus using 1 mm isotropic diffusion kurtosis imaging in 363 participants aged 5–90 years. HippUnfold enabled automated subfield segmentation and unfolded hippocampal maps. Whole‐hippocampus showed distinct lifespan trajectories: volume, quadratic; MD, negative Gamma Variate; FA, positive Gamma
Pablo Stack‐Sanchez   +3 more
wiley   +1 more source

Microglial-Derived IGF-1 Serves as a Regulator for Neuroimmune Homeostasis During Viral-Induced Demyelination. [PDF]

open access: yesViruses
Scarfone VM   +13 more
europepmc   +1 more source

MIF‐MAPMS: Enhancing identification of myelin autoantigenic peptides in multiple sclerosis through multimodal information fusion

open access: yesProtein Science, Volume 35, Issue 8, August 2026.
Abstract Multiple sclerosis (MS) arises from an autoimmune response in which the immune system erroneously targets myelin autoantigens within the central nervous system, leading to myelin degradation and subsequent neurological dysfunction. Identifying myelin autoantigenic peptides (MAPs) is therefore critical for understanding MS pathogenesis and ...
Watshara Shoombuatong   +4 more
wiley   +1 more source

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