Results 201 to 210 of about 94,021 (297)

Diabetic Autonomic Neuropathy and Impaired Inflammatory Reflex

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 6, November 2026.
The cholinergic anti‐inflammatory pathway under normal and diabetic conditions. In the normal state, vagal activation through nicotinic acetylcholine receptors helps regulate immune responses and suppress excessive inflammation. In diabetes, impaired autonomic function and dysregulated cholinergic signalling weaken this anti‐inflammatory pathway ...
Narges Dastmalchi   +3 more
wiley   +1 more source

The Maintenance of Dysmyelinated Small‐Diameter Axons by 14‐3‐3s in the Central Nervous System

open access: yesGlia, Volume 74, Issue 11, November 2026.
Dysmyelinated small‐diameter axons are maintained in teneurin‐4 deficient mice at the age of 1 year, while axonal damage is observed. 14‐3‐3s are highly expressed and suppress the progression of the damage in these axons. ABSTRACT In the central nervous system, myelin formed around nerve axons by oligodendrocyte enables efficient conduction of action ...
Nanako Yamada   +15 more
wiley   +1 more source

Hemi-capsulo-rhombencephalic demyelination

open access: yesAnnals of Indian Academy of Neurology, 2010
Suresh Chandran C   +2 more
doaj  

Recombinant rat heat shock protein 70 (rrHSP70) may promote remyelination by regulating microglia/macrophages and oligodendrocytes in a toxin-induced demyelination animal model. [PDF]

open access: yesFront Immunol
Song J   +17 more
europepmc   +1 more source

A case of acute lithium encephalopathy associated with elevated myelin basic protein levels in cerebrospinal fluid [PDF]

open access: yesPCN Rep
Abstract Background Acute lithium intoxication can cause severe central nervous system (CNS) manifestations, sometimes leading to long‐term sequelae known as the syndrome of irreversible lithium‐effectuated neurotoxicity (SILENT). However, its underlying pathophysiology remains unclear.
Yokoyama T   +3 more
europepmc   +2 more sources

Consensus Guidelines for Diagnosis and Management of Pyruvate Dehydrogenase Complex Deficiency

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Primary pyruvate dehydrogenase complex deficiency (PDCD) comprises a group of monogenic disorders caused by pathogenic variants in genes encoding subunits of, or regulatory components affecting, the pyruvate dehydrogenase complex. The clinical phenotype spans a broad continuum, ranging from early onset congenital lactic acidosis to infantile ...
Nandaki Keshavan   +23 more
wiley   +1 more source

Polyomavirus Drives Cerebellar Lesions in AIDS Monkeys With Ataxia

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Chronic SIV‐infected macaques with ataxia develop severe cerebellar lesions driven by simian polyomavirus 40 (SV40) infection. SV40 preferentially infects cerebellar granule cells, inducing pyroptosis and an aberrant proliferative state. Pyroptotic neuronal injury promotes microglial recruitment and activation, amplifying local neuroinflammation and ...
Tian‐Zhang Song   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy